A section specially for our members who have been affected by herpes for a long time and are all too familiar with what life can be like with this little virus. Please share your experience with us here.
Lol, a thousand guinea pigs. I think you raise a good question (though it's a bit sad that a 1000 guinea pigs might have to die).
But every every preclinical study I know, also uses a fairly small number of lab animals. It's rarely more than a few dozen. For example, the EDITAS proof of concept ocular herpes solution tested in 36 animals, of which some got placebo, and some got AAV with no editors. So testing in only a handful of animals seems to be the norm. So I wouldn't read into that caveat too much, if I were you. But whether that vaccine can ever enter human trials, that I don't know.
Some things I've read seemed to suggest that ppl are kind of down on the idea of testing vaccines, on account of the failures. I hope that's not the case.