Leaderboard


Popular Content

Showing most liked content since 12/20/2016 in all areas

  1. thatsmycat

    Theravax news story

    Awesome news story about Theravax- we finally get to hear the voices behind the movement! Thanks @Rational Vaxxer for being so brave to come forward ! This is so much hope! http://newyork.cbslocal.com/2017/01/06/herpes-vaccine/
    18 likes
  2. Rational Vaxxer

    Theravax news story

    That was me. So thank you
    16 likes
  3. Dr Halford has quite literally devoted his entire life to this cause. With the only incentive being to help his fellow men. We will not rest until this disease is defeated.
    14 likes
  4. It seems like the most active and informative thread on Halford's vaccine and HC member Rational Vaxxer was deleted? Thanks to the members who couldn't resist constantly provoking needless arguments instead of promoting healthy and respectful discussion. As I feared we are back in the dark again having to wait for news to filter down to us instead of getting a first hand account from Vaxxer and RVX Investor. This thread is for pro- Halford comments and supporters. I want to hear from them and not the mud slingers and naysayers that love conflict. Please ignore the ones who are anti Halford! Please keep us posted Vaxxer & Investor. There will be a day that you and Halford will be vindicated and the proof will be indisputable!
    13 likes
  5. Agustin Fernandez III

    Found on Halford's Blog

    I understand the reluctance to speak out. It is scary. We are here, hoping to change that.
    13 likes
  6. Chip Clark

    GENOCEA

    We've said previously that we'd announce Phase 2b clinical results this month, looking at clinical responses vs placebo 6 months after dosing. We also said we plan to initiate Phase 3 trials, assuming success in 2b, in the second half of 2017. I'll continue to keep the forum updated on our progress against these plans.
    13 likes
  7. OhFuckMyDickHurts

    GENOCEA

    @Chip Clark thank you for answers to my questions. #4 a honey melittin sequence was added to gD2 to presumably enhance production and immune response in a 2013 GEN-003 guinea pig study. I don't know if you're referring to UofW but I noticed they get $$$ from Genocea as well as AiCuris. I respectfully want to point out that Lawrence Corey is probably primarily the number one hurdle to alternative effective HSV treatment options in the USA because he is behind the licensing of acyclovir and valtrex pills. Lawrence Corey is likewise possibly also biased against live HSV vaccines. Here is a video of Corey talking about live vaccines [Source]; however that results he talks about can be eliminated by removing HSV's ability to enter T-cell/DC's or by adding a therapeutic protein [source]... does he care about that... likely not...... @Agustin Fernandez III (of RVx Vaccines) if you ever wanted to lobby NIH for funds you'd probably have to convince them Corey is clearly wrong. Corey and his team are behind GlaxoSmithKline wasting 10+ years pursuing Herpevac trial and wasting $$$$ millions of dollars and why we don't have options other than pills he was behind. What happened? In 2005 GlaxoSmithKline funds Lawrence Corey and others to do a large human trial of DISC HSV-2 live vaccine (proposed in the 1990's) in 2005 as its shown to be quite effective as a prophalaxtic and as a therapeutic in guinea pigs. [LINK]. However these asshats in a Phase 2 human clinical trial gave a paltry doses to the participants of (6×10^6 plaque forming units (pfu) aka 6 million PFU). The dose is LOWER than what the guinea pigs got in the prior experiment. Of course they don't get an immune response, reduction in symptoms, recurrences, etc. They therefore wrongly concluded we in the HSV-2 community need alternative and more "potent" approaches than live vaccines.... GSK then funds gD2 subunit vaccines and wastes years and millions of dollars. RVx with William Halford and his live vaccine HSV-2 ICP0DNLS based on his [unpublished] article online in 2016 states he tried various doses and eventually tried 2x10^8 (200 million PFU) and got great results and it was quite immunogenic. He could potentially go higher as the FDA has approved a skin cancer treatment using HSV attenuated strains up to 400 million PFU.... @Chip Clark if you wanted to acquire live vaccine guys, RVx looks like an interesting acquisition.... BTW I'm biased for live vaccines as I've seen them dramatically reduce OBs from days to nothing and potentially can be altered to have significantly better durability (what I said Corey was wrong about) whereas I see other gD2t vaccines basically just drop a day off an OB... There are other research papers out there including numerous HSV-2 proteins and there is a limit it looks like with what you can get an immune response with. Adding more and more recombinant proteins to increase the immune response frankly doesn't work unless you're using a live vaccines. You're never going to get the complete plethora of antibodies and T-cells necessary without it. BTW @Agustin Fernandez III you might want to consider pointing out to GlaxoSmithKline their DISC research they paid millions for was at a significantly lower dose and that you guys are better than DISC in guinea pigs, in human subjects you blew their results out of the water and maybe they ought to help fund you guys further.... albeit that assumes it doesn't rekindle their interest in DISC and compete against you.... would be interesting if Bill compared NLS vs. DISC as a way to convince them...
    11 likes
  8. Hi everyone, I have had so many requests for answers, i know i won't have them all, but i could not ignore everyone that reached oout. Our only goal at RVx is to help and i am here to do the best i can. Please ask me anything, you need to. I will try and answer to the best of my abilities. Rational Vaccines is not a big Pharma company, we are just like all of you, a couple of regular folks, that really care about eradicating this virus and we are here, for you.
    10 likes
  9. Rational Vaxxer

    CBS 2 interview for Rational Vaccines

    The data is showing some very promising results so who knows what's going to happen within the next year. They make may make more discoveries and turn it into a Cure. Who knows. Time will tell
    10 likes
  10. people, please RELAX. i have told almost everyone here in this thread that shedding studies WILL HAPPEN. its not like RVx doesn't know that we eventually need to do them, ok??? this is research by a small smartup, things will happen in DUE COURSE. and as quoted above, yes HSV1 is also a concern, OK??? RVx has patents for both types, but so far the HSV2 vax is working on HSV1 anyway. give RVx some breathing room!!! attacking RVx or being negative or just haranguing RVx doesn't help anything. read the blog and the posts of RVx folks here and you will know what we know to the best of our knowledge, ok? Agustin is here to answer legit questions, not be deluged with nonsense.
    9 likes
  11. Today, Dr. Halford has written directly on his blog imploring people to sign this petition so he can go in front of congress. https://liveherpesvaccine.com/2017/01/15/please-consider-signing-a-petition-to-get-me-a-moment-with-congress/ I know many of you are reluctant to sign as you are worried that your identity may be exposed. HOWEVER, remember that signing this petition does not mean that you are telling the world of your HSV status. You are simply saying you care about this issue. Wouldn't you sign a petition for any other cause that may not affect you personally, but does impact your friends or loved ones?? Have you ever participated in any fundraisers or "Run for the Cure" for cancer causes or HIV/AIDS awareness or anti-discrimination or cystic fibrosis or juvenile diabetes or ALS or Parkinsons or heart disease......... Does that mean you have that disease/problem!?! No, it means YOU CARE!! Approach this in the same way. SIGN THIS PETITION NOW!!!! Every time you get on this forum to vent, complain, and connect to others, just think about whether you have done your part. Hiding in the shadows is not being proactive and fighting for a solution. A solution for a medical condition that you think about every day, that you cry about, that you feel shame for, and wish with all your heart was gone/effectively treated.
    9 likes
  12. Chip Clark

    GENOCEA

    Re UW: we do collaborate with them. The $ they receive from us is, I believe, 100% for the execution of clinical trials as one of our sites. We collaborate mostly with Anna Wald who, I believe, trained under Larry or at least worked with him in the past. We do not collaborate with Larry but my team has, on occasion, interacted with him. I have no reason to believe he would be against any credible effort to develop effective vaccines to prevent or treat HSV infections. To me, his career demonstrates the opposite. You make some comments about specific scientific decisions he and/or GSK made. I neither know the details nor, honestly, do I know the science well enough to comment on those decisions. We are watching the development of live vaccines with interest. In addition to RVx, you probably know Sanofi Pasteur have made a significant investment in developing one they licensed from David Knipe at Harvard. I believe they have been conducting early human trials to evaluate its potential both as a prophylactic and as a therapeutic. I also believe they should be announcing results imminently (their most recent statements said "end of 2016" so they're a bit late).
    9 likes
  13. LilyMae

    HELP! IM FREAKING OUT

    Hi @lali. Also, your sex life is DEFINITELY not over. ☺ It's got a crimp in it for now. But that will work itself out. IT REALLY, REALLY WILL. I promise you. You're going to need some time to yourself to get used to this new thing and let your body adjust to how it needs to heal. Be patient. Be compassionate. Both with yourself and with your body. Give yourself the deep, deep gift of time and love. Lots and lots of love. I've had hsv since I was 24. This month I'll be 46. Tomorrow is my 12th anniversary with the most amazing man I've ever met. He's smart. He's funny. He's deeply decent. He's tall. He's better looking than me. He is the kindest man ever. He's hsv negative. And he loves me like I am the air he breathes. This is out there waiting for you too. You're going to be okay. You will find your way through this dark, scary time to find a great and marvelous love. Probably more than one! Sending you hugs.
    9 likes
  14. Rational Vaxxer

    CBS 2 interview for Rational Vaccines

    Interview for rational vaccines on CBS channel 2 news 1/6/17 http://newyork.cbslocal.com/2017/01/06/herpes-vaccine/
    9 likes
  15. HopeComing

    Theravax news story

    At least with ths vaccine being here it will be possible to date mostly normally and with our knowledge of the virus we can make aware people and potential partners that herpes just isnt a bit deal anymore thanks to these advancements. With the coming cures and vaccines we can all come out of the shadows and let people know how silly theyve been the entire time. The stigma will be gone.
    9 likes
  16. RVX Patient and Investor

    CBS 2 interview for Rational Vaccines

    i don't want to get bogged down in the debate here, i think people should respect both sides, those who think its awful, and those who think it could be worse, but this is true: HSV has taken lives. just by itself biologically speaking, thats rare. but as a motive for suicide, OR as a transport vector for HIV, HSV is insidious. we can walk and chew gum at the same time. we don't say "lets not research heartburn" just b/c cancer is still out there. the amount of resources poured into cancer, which is totally deserving, dwarfs the little tiny bit of resources HSV gets. i think it speaks volumes, that Dr.Halford continues his quest to eradicate herpes, EVEN WHILE he is stricken with a very serious cancer.
    9 likes
  17. http://www.news-medical.net/news/20161220/USPSTF-recommends-against-routine-serologic-screening-for-genital-HSV-infection.aspx I will speak my mind on this one! What the hell are they thinking!!! Let's just make the problem WORSE by allowing people to ignorantly have no idea they have the virus and spread it MORE!! Very careless attitude. Particularly including that pregnant mothers don't need to be tested! Moronic! How about we sweep the whole herpes pandemic under the rug and pretend it doesn't exist? (Sarcasm) Some lunatic who never has to deal with disease probably made this a thing. Stupid stupid stupid people! The issue must be ADDRESSED not ignored!! ^^This makes me angry.
    9 likes
  18. please see the actual post: https://liveherpesvaccine.com/2016/12/23/hippocratic-oath-missing-from-hsv-2-vaccine-development/ after reading that, consider the following: 1. Halford is dying of cancer. would he waste his time on nonsense? 2. the vax has been put into people over the years, some in trials, some not. it has been, for most people, a much better deal for them than not getting the vax. 3. would he put all his time, effort, and money and reputation into a cause that is hollow? 4. would u, or the avg reader, knowing just what u know right now, jump on a chance to have his miracle sauce jammed up ur bunghole if thats what it took? damn straight u would 5. not everything has a pair of fancy black shoes and a tux to wear. sometimes it comes dressed in a burlap bag but with weeds hanging off it, but by god its whats getting the job done, ...all pinheaded question don't need exhaustive answers. now some few might be legit here or there as to what makes its working; not that is it working, bc clearly it is. people complain about big pharma, and sometimes what they say is actually true. but you rarely hear about big academia, you know those egos that have ta dress up their failures and attack others approaches so that they can get more go'vt funding and institutional funding. Halford represents a threat to big academia, their so called conventional wisdom, and most of all their big egos which need to keep the plates spinning so they can do the money rain dance, b/c his approach is different and uses private funding. maybe some valid points were made, maybe they do want drs to employ dick ID techniques on a near hourly basis to avoid the horror of a patient self reporting an OB, but by god they need to step back from the myopic microscope of furious negativity long enough to see the big picture, does this treatment work??? the next trials, done by a company who is a self-starterup, has no big pharma or big academia behind it, is the turd in the punch bowl, and so far is the only one u can trust for just those very reasons! we can only succeed if the product succeeds, not if our dr buddies love it and so we get more tx money. 2017 is gonna be huge. and i got a pretty good idea who the bad guys are.
    9 likes
  19. Hi All Many questions, so little time. we are putting in 12 hour days to keep this moving, so please forgive me for not being more present. Let me try to address a few of the more pressing questions. Trials - P2 - 4th quarter 2017, - shedding study will happen, but it is down stream. Why? Because the most pressing concern is ending the debilitating pain so many people deal with on a daily basis, so the next trial is for efficacy of the therapeutic effect and hopefully perfecting the dosage. HSV1 - HSV2 Our Data so far seems to indicate that our HSV2 Vaccine does help to improve and often eliminate all the symptoms related to HSV1 infections as well. More studies are needed, and we do have a specific HSV1 Vaccine that will be studied further, however for most cases of HSV1 it seems that the THERAVAX HSV2 can help. Why we believe this could be a functional cure? We have very strong data that indicates Dr Halford's Vaccine will work as a preventative vaccine. This is the primary purpose of a Vaccine and in this we think Dr Halford's Vaccine will work wonders. Luckily this Vaccine also confers tremendous therapeutic effects to persons who are already infected. So reduced/no symptoms + preventive inoculation of future or current partners to prevent infection = a functional cure. I can tell you that we suspect based on many animal studies that Dr Halford's Vaccine WILL reduce shedding in a real way, when compared to anti Virals and the current standard of care, but we do not have enough science in humans to support that and i will not over sell to you. I personally believe that shedding in humans will be reduced in very much the same way it has been reduced in animal models, but my believes are NOT a substitute for scientific studies... We will do them, as soon as we can. First things First, end the immediate suffering. Did i miss something? I'm sure i did, long day, very tired. Please feel free to keep asking, i will keep answering as i can.
    8 likes
  20. Sweetheart92

    I disclosed for first time...

    I have had GHSV-1 since I was 19yrs old I stayed in the relationship for over 6yrs and now had been single for over 2yrs I met someone about November and we are now Officially a couple we haven't done anything besides kiss and he is ok with that he is the sweetest man I have ever met and I'm really falling for him! This is going to be the first time I have ever needed to tell a man what I have. I chickened out twice already just because I have horrible anxiety and I'm letting it get to me which I know I shouldn't but today is the day for sure I know I need to do it because things are going the sexual route and I would never do anything without telling first... I'm just scared of him rejecting me... My family says he seems like a very understanding guy so I'm hopeful! I will tell you all how it goes in the next few hours when he comes to see me! Wish me luck!! *Update* It went amazingly!! I was stressing out for nothing I knew he was a great guy from the begining! He was so sweet and said that shit ain't gone make me leave you I'm here for the long run I promise he kissed me and he proceeded to ask me sexual questions I told him I will be on meds and we use protection he said of "course but I won't need protection all the time" I'm like yes he said "I don't plan on being with anyone else ever but you!" Wow I am so happy! Thanks for listening to my experience yal!!
    8 likes
  21. YammyTea

    I can dream...can't I?!

    Hello all! I've been on this journey since July 2016. There was a time when I would visit this site multiple times a day....mostly while I was in tears. I've met some wonderful people here...you know who you are. If it wasn't for this virus, we probably would've never crossed paths. I've tried to keep up with all of the research for vaccines and cures regarding HSV. I must say that the threads in the research area...well, I will keep that thought to myself. On to my dream.... 1) I dream of one day getting the call scheduling my appointment to have this virus eradicated from my body for good. 2) I dream of a day I don't worry about transmission 3) I dream of a day that I don't have to use the words disclosure, positive results, antibodies, IgG, IgM, Western Blot, "The Talk", Valtrex, outbreak, and discordant 4) I dream of a day there is a prophylactic vaccine available to everyone 5) I dream of a day when the medical community wakes up....if it is not HSV it will be something else that everyone is clueless about. 6) I dream of a day when the medical community tells you about the options you have regarding your health 7) I dream of a day when all people ask more questions and demand more from the medical community 8) I dream of a day when I can eat a brownie again without worry 9) I dream of a day when I can look at coconut oil the way I used to...lol 10) Although the site is great...I dream of a day when someone knocks the Hive down because it is no longer needed. Just give us a chance to say our goodbyes...ok 11) I dream of a day when children and babies are no longer at risk for HSV. (This is sensitive for me...as a teacher I would see this and to think these children have to cope with this virus, some from infancy) 12) I dream of a day when regardless of color, religion, fear, shame, and doubt all those with HSV (or should I say those who had HSV) stand together and make some noise about how we were left in the shadows. Please don't bite my head off for how I feel or for my next statement. I am a Christian and yes, I feel that I have this virus due to my disobedience. Notice the letter in bold. I am praying for a cure even though I don't desire it...heck I don't deserve a lot of things....hence the word "blessing". I am not only praying for me, but the entire community to be freed of this virus. "Remember that God’s healing may include medicine and professional medical help." I found that tidbit on a Christian website. I will now step down from my religious soapbox. Hugs, Yammy
    8 likes
  22. No man! DO NOT DO IT! I was diagnosed recently and still feel pretty bad about my situation but its gonna be ok. Hell man, my situation cost me my girlfriend of 7 years and who knows what else but I know it aint worth killing yourself over. This forum will help you like you wont believe. Lots of good people on here to help you get through the rough times. Just DONT freaking do it! SERIOUSLY!
    8 likes
  23. Voyager2

    Theravax news story

    I'm so happy the mainstream media (CBS) has picked up on Theravax! I have a feeling 2017 is going to be a big year for all of us.
    8 likes
  24. Chip Clark

    GENOCEA

    Here's a new update! This morning we've announced positive Phase 2b clinical results vs. placebo @ 6 months post dosing. You can find the press release here: http://ir.genocea.com/releasedetail.cfm?ReleaseID=1006561. We're obviously super-happy about what this means for the program. We're that much closer to getting this to you! We're on track to start P3 this year. Happy to field questions, as always. I appreciate your patience on timing - much on my plate today/tomorrow.
    8 likes
  25. Chip Clark

    GENOCEA

    I wasn't aware of this, but will stay out of it. My job is to ensure Genocea advances GEN-003, balancing as always patient safety, clinical development speed and program breadth. If GEN-003 were to obtain regulatory approval, then docs, patients and payors will decide if GEN-003 is as much an important new treatment option as we believe it is. I do not see my job as commenting on other programs, whatever their merits.
    8 likes
  26. You are free to disagree here. Personal digs, however, are not appropriate. It is disappointing that I have had to say this multiple times. Please think before you post.
    8 likes
  27. I know you are very angry about contracting herpes, and are frustrated. But this isn't productive and doesn't help anyone. There will be more data as to the efficacy in terms of shedding in the future, but is it not enough that there is hope in the very near future? My understanding is that, without any vaccine and just the odds of transfering the virus is about 10% from men to women, 4% women to men (sleeping with the same person over one year on a regular basis), then with use of say current antiviral drugs 5% (2% women). For men, that's 5% risk over a year with a reduction in shedding by 50% by using antivirals. So even if the vaccine was 10 x more effective than the antivirals (500% reduction in shedding), which from what I understand, the vaccine (theraputic) will be approx a minimum 50x more effective. Transmission rates would be at levels that would be not be a risk for transmission and this is in the short term! Then think of the preventative vaccine in the future for partners, the CrispR gene editing and drugs in the future which potentially can completely cure the latent/dormant infection, you my friend are living in a time of immense hope, but you really need to start coming to peace with where you are with it right now as it obviously hurting, as it has and still does to me. Just a little maths stolen from the link below, but based on a 4% transmission - 120 (12 months x 10 sexual encounters per month). This makes the possibility of spreading the virus during any sexual encounter .0003%, or 1/3,000 (.04 / 120 = 0.00033333333333) based on a 2% transmission thats 1 in 6000 odds! 1% 1 in 12000 odds. Coming back to the vaccines and other treatments. Herpes will be curable in the next 5 years. I am not a doctor, but it is now a fact, no argument about it. All the best.
    8 likes
  28. While I wish the peer review had been more "generous" in their response--I see it (knowing as little about it as I do) as part of the academic "process". Perhaps it will give Dr. H a little insight into what they see as missing and provide him with what to shoot for next time, if he so chooses to go that route again.. Regardless, let it be understood the Peer Review process and issue will not stop his forward motion. He is an out of the box, fearless ("ballsy" if you like) driven and determined man on a mission to help ALL of us, the True Believers and the doubting Thomas's alike-which is an overwhelming positive. Is there more any of us could ask for?
    8 likes
  29. HC-Support-Team

    GENOCEA

    OK, this is becoming a challenging thread to Moderate. I propose that we begin two new threads; - one thread for Halford updates / one for GENOCEA, and - another thread for debating the technology What do you think? We need to be able to hear and express both sides of the argument, while also having easy access to the important information. Shenda
    8 likes
  30. RVX Patient and Investor

    Post Pro Halford & Theravax comments here

    thats a great post, and i appreciate it, and i certainly believe you are correct or i wouldn't have put my money into it, but even RVx told me prior, there are no guarantees... biomeds are a notoriously fickle field. still, i'm a true believer. there really is no new news since the initial findings were reported, except that RVx is trying to get the big 2017 trials going. but i do plan to post as i hear things that i'm cleared to share.
    8 likes
  31. herpes454

    Can't live with diagnosis

    Bruh, I had a "30 minute stand" with a former friend of mine one evening during which there was about 5 minutes worth of oral contact and less than that worth of vaginal contact. I got HSV2 from it. Oh did I mention I'm married and had been faithful to my wife for almost 20 years prior to this happening? Literally since I was 17yo not had any sexual contact with anybody other than my wife. She was the only person I'd ever been intimate with. I came home and had to tell her what happened because it was the right thing to do, assuming my marriage was over...and then a month later finding out I had HSV2 and having to cope with the ordeal that comes with finding out about HSV while saving my marriage and coping with the guilt that I had destroyed our safe and sterile sex life that I had taken for granted for so many years. To say the stress and disgust I had in myself was overwhelming is the biggest understatement in the universe. I was literally sick with shame and it took months to recover from the stress. Fast-forward 1.5 years and our marriage is better than ever, we've been having unprotected sex for over a year now and to my knowledge she still doesn't have it (never had her tested - no point), I take antivirals daily just for caution and generally don't have any symptoms day-to-day, and life is good. On our final day of couples therapy a while back she literally said that what happened actually worked out for the best in our relationship (though I wouldn't recommend this route to anybody!). I only ever really think about HSV when I need to refill my script or when I'm on these boards. Point being, your life is hardly over. If I can get through this and have a strong and meaningful relationship you certainly can. In a year you'll look back at this thread and wonder WTF you were thinking. Trust me.
    8 likes
  32. Snippy, All great questions. We are gearing up to begin a P2 now. We will be studying Efficacy in this trial. Hopefully we can replicate the therapeutic effects we saw in our P1 safety and tolerability trial. There are two host countries for this upcoming trial, and it is going smoothly with both of them. As per your final question RE: THERAVAX... the answer is YES... as planned...
    7 likes
  33. Never Surrender

    Theravax news story

    If you need support, there are other sections on this website for that. We all are struggling with this virus so I can understand your frustration. But If you do not have specific information other than an uniformed opinion, than maybe you should withhold it as it is not constructive for many of the rest of us.
    7 likes
  34. snippy43

    Theravax news story

    i don't believe your negative chatter is at all useful. the vaccine has proven success already in a small study. perhaps you should investigate what is involved with getting such a product to market and you may be more appreciative of the efforts!!
    7 likes
  35. fixme1

    Herpes Cure

    Hes clearly destroyed himself mentally to a point where he believes that science wont prevail one day. it will. I suggest you keep it to yourself cause not everyone on here is in the best of ways some days. this is a support forum we are here to keep our heads up
    7 likes
  36. I signed. Not interested in "exposure". Who cares, who is gonna search this list for names? People have better things to do than that. Don't be paranoid, do the right thing, sign!
    7 likes
  37. Evaluate

    GENOCEA

    @Chip Clark, I want to say your comment about the value of an independent party to verify data speaks a lot about your leadership and philosophy of doing business. HSV aside, your commonsensical approach and the way you comment (cautiously and accurately) is terrific to see. That fact that you engage here with us, when there is minimal benefit financially to doing so, blows me away. Genocea is lucky to you have you as a CEO.
    7 likes
  38. LilyMae

    So now I'm single with herpes

    Hi @Reka. That stinks. It's hard and it hurts now. Hug. But in the long run you're probably better off. I know this is going to sound like bs to you right now because you're in pain and feeling alone. But really try not to take it personally. It's not about you. And it's not about hsv. It's about him. His own fear. That's not a partner to walk with you in all the uncertainty that is human existence. Good riddance, little man. Hold your head up high. You will get through this. You don't need him. And when you're ready, you'll find someone who is amazing and just right for you.
    7 likes
  39. phil UK 1972

    Please help me , i feel like killing myself

    hi, sorry to hear you are going through a bad time but i understand how upsetting it is when you get your confirmation. Firstly, your dreams and life havent stopped...far from it. You will take abit of time to get your head around things but believe me your life will get back to normal far quicker than you think. I have had the virus for over 12 years now and i lead a totally normal life etc etc.... Honestly, theres far worse things out there you could have caught.
    7 likes
  40. Wow at your lack of compassion. Thank God, Dr Halford, you know the man who has cancer rather than herpes and wants to find a cure for all of us who has this shitty virus doesn't share your belief.
    7 likes
  41. I am thankful for him and what he is doing for people in light of his own personal health is why I have faith in him. He could have easily given up but he choose to press on and that is why we have to remain positive.
    7 likes
  42. Please. I was just trying to be hopeful and say that we can make it through this thing and that there are people whom upon receiving a stage 4 diagnosis are faced with the possibility of death. When a friend of mine had cancer, I saw the fear in her eyes. She was lying in bed facing death. She ended up passing away from it and her wish was to see her daughter grad from college and she never got that wish. I know there are people who suffer from herpes virus, we all are affected by it differently so I am not trying to discount that. Your tone of voice and outlook is why there is so much negative thoughts on this board.
    7 likes
  43. I don't know who said it on here or where I read it but the hardest part is the fear and rejection that comes along with having it and not the actual virus itself. I just found out yesterday that a co-worker's daughter was diagnosed with stage 4 cancer and she's in her 40's. That made me pause and think about what I'm dealing with is a walk in the park in comparison.
    7 likes
  44. Rational Vaxxer

    The 100 million

    The struggle of every day life can be exhausting, like trying to untangle your iPhone earbuds while driving. While it is obvious that many decisions that we make are flawed, it is obviously human to be curious and take chances. If anything, it is in this curiosity that makes us human and also quite fallible. Sometimes life can be hindered by choices or the lack there of. I think this is the main reason why people who have lifelong diseases struggle with every day life. It is the lack of choice and the hindrance of other available choices that can sometimes make life difficult. When it comes to HSV most people do not even think about it. It is the small percentage of the human population ( about 100 million ) that suffer in a terrible way, that struggle with the lack of choices. It is in that choice that a mistake was made. A mistake that many people are reminded of every day for the rest of their lives. Every time they look in the mirror, and the mirror looks back and says "hey remember that mistake you made?" It is that constant reminder that many of us have a problem with and must learn to deal. Many of these 100 million are the worst case scenarios. They are the stories that you hear about on the Internet or in the pictures you see in slideshows discussing the gross to small school children on the dangers of STDs. It is the slap in the face reality of the obvious. While our choices may be limited, we do have a choice on how we look at life, it is not always easy and for many, we struggle to find some light at the end of the tunnel or a glimmer of hope for relief. Being a recipient of the HSV vaccine has changed my outlook and has given me a brighter perspective. The simple fact that it works, has changed my life. My only hope is that many will soon benefit from this vaccine and also benefit and feeling better. Better about having a choice… One that can give hope to feeling human and whole again.
    7 likes
  45. Never Surrender

    The 100 million

    As Rational Vaxxer posted above, there are reasons for optimism. Setting aside the data published in October by RVX, reminder that the following members have posted positive accounts of their experience with Theravax: @Sweet7One of the first recipients was symptom free for two years, then had three bouts of neuralgia during year 3, and then had an OB three years after receiving the first shot of the vax (this is very encouraging to me) @RVX TRIAL #1 MEMBER OB free for 8 months as of mid December @Norwegian123 Only took one shot but this pretty much cured her neuralgia (which is my worst issue by far) @RVX Patient and Investor Has taken the vaccine and thus far had a positive experience. Yes some people discount him because he is an investor, but I do not. I very much appreciate his comments on here and his investment. Where else would angel money come from for RVX if not from current sufferers of herpes? Then of course, we have the brave (and public) account by @Rational Vaxxer himself. Also appreciated. Yes, there was one negative account from the trial on here, but we have to keep in mind that this is just the beginning with this vaccine and it can be boosted or tweaked in terms of how many shots etc to enhance the effectiveness. And in the future we have potential advances in CRISPR with Editas and Excision. Farther out there and still a lot science to be worked out, but hopefully Theravax is a bridge to reduce symptoms for now. Not wearing rose-colored glasses, but objectively there is more reason for optimism now than in years past.
    7 likes
  46. i do want to point out that Halford is the ONLY PERSON ON THE PLANET developing a live attenuated vax for HSV. that means all the "reviewers" are fully vested in their research which runs counter to his. this is about ego, not science. Galileo wasn't wrong just b/c he was the only one saying it at the time. 2017 is going to be a big year for RVx. the trials will answer a lot of questions. til then, no one else is even close to getting a product on the shelf, so everyone who isn't mentally ill should be rooting for Halford, not tearing him down for specious reasons.
    7 likes
  47. Halfords post was informative in the sense that it shows his passion for finding a new solution to this virus. Anybody who is willing to self inject something repeatedly to prove its safety is clearly committed. I appreciate his determination. But I am not surprised by the responses from the other academic types. It's going to take time and DATA to change deeply entrenched views from those who have a vested interest in the status quo. And objectivey other drugs on the market have gone through so much rigorous testing on hundreds of patients, and regardless of how much progress has been made on such a small group of patients by RVX, it will take a larger data set to start to move mountains. I have applied for the next test with Halford in part to be what I hope is more good data on Theravax. If selected, I will gladly fund my travel and accommodations as I am so tired of battling the symptoms of this virus.
    7 likes
  48. Bill, if you see this, know that we are committed to you.
    7 likes
  49. Bill, Merry Christmas and Happy New Year! Thanks for all you do and especially for keeping us informed!
    7 likes
  50. Chip Clark

    GENOCEA

    Respectfully, I disagree with you, fixme1 and I95. We have tested GEN-003 in about 500 patients so far. Of those 500, only approximately 100 have been tested at the 60 micrograms/antigen + 50 micrograms/adjuvant dose that we think will be best for patients. Yes, our efficacy data are encouraging. Yes, the tolerability profile thus far seems acceptable to patients. But that is way, way too few patients to give real confidence that GEN-003 will work for the millions who might try it. If you see the same profile in a few thousand patients, then you can be much more confident. And so far you largely have to believe our statements about our data because independent parties are just now starting to validate them (through peer-reviewed publications, presentations at scientific meetings, etc.). I know we are being truthful with the public about our results, but from a society's perspective it is much better for someone independent to verify that we are being truthful, because we can be biased (we genuinely want GEN-003 to work for people, and we want it to be available as quickly as possible) and we have a financial incentive to get it on the market as quickly as possible. In other words, you actually shouldn't 100% trust me until an independent party says I should be trusted. That is why we need the FDA. I would love to be faster. I am always urging my team to find ways to be faster. But we have to do this the right way, or we could screw this up for the millions who could benefit from GEN3.
    6 likes