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  1. This week I went to an Urgent Care with the complaints of vaginal itching.. Today I just so happened to look at my visit summary and noticed that Herpes Virus 8 DNA Real-Time PCR was ordered. Is this test normally used for genital herpes??? I’m confused
  2. Hi. We all know that in theory it usually takes 12-16 weeks (sometimes up to 24 weeks) to get positive IGG blood test for HSV2. What are your personal experiences of testing positive for HSV2, i.e. time since exposure? And IGG score? Can you also state if you had HSV1 (oral or genital) and took any Antivirals prior to IGG testing? TQ
  3. justagirlxox

    swab tests

    Hi, I have a friend who a few years ago had a swab test done which came up with hsv2 however still to this day they test negative on every blood test including western blot. Apparently they only had bumps/blisters the first few weeks but nothing has happened since, including no tingling or soreness and its been years for them. Theyve never gotten a positive blood test, always negative. What are the chances of a false positive swab test? Is it possible their results were mixed up at the lab?
  4. New guy here. I am posting in order to add to the body of evidence, even if anecdotal, that the herpes blood tests are indeed fallible and, especially as this relates to so-called "atypical" herpes, the fact that herpes can be extremely difficult to detect with the current medical technology. I also wanted to share my experience that most of those I've come across in the medical profession have been at best misguided and at worst totally dismissive about H. In my case, I briefly dated a girl who was H1 and H2 positive. She disclosed this to me and told me she was on daily antiviral therapy, which suppresses the virus. I was totally uneducated about H at this point in my life and assumed that the pills would prevent me from acquiring the virus. I also consulted with my PCP who told me that if I did not kiss or become intimate with her when she had a breakout then I would not contract the virus. Well, I am 99% certain I have OH now. I've read many posts on this forum in which people call this a benign virus that basically doesn't affect your life much. That may be true for many but not in my case. For the past two years I have had nearly constant lip and facial symptoms (tingling, burning, throbbing, flushing red, random stabbing pains) that are closely consistent with OH except for the fact that I never get a full on lesion that can be swabbed. I did have a brief period of about 3 months once where there were virtually no symptoms. But other than that, this has been an every day ordeal for me for the past two years. Prior to this known exposure I had never in my life experienced anything like this. Not even close. I think about these symptoms on a 1-10 scale. Some days it is a 1 or 2, with some minor and brief tingling or burning. Other days it gets up to an 8 or 9, where a patch of my lip throbs, burns, or tingles then turns bright red for about an hour before subsiding. Basically, everything except a full-on lesion. What testing have I done? I have had about 7 or 8 IGGs, two Western Blots, several culture swabs of symptomatic areas (again, I do not get full-on lesions), and about 3 PCR swabs of symptomatic areas. All negative. My highest IGG results were 0.1 on HSV1 and 0.14 on HSV2. The IGGs were spread out over about two years. The Western Blots were done at 14 months and 21 months PE. I have seen two general MDs (not including urgent care MDs), three dermatologists, an immunologist, and a neurologist. I even had a brain MRI. Out of all the doctors I saw in person , I found only one that actually believed it was possible that OH could be causing this. This was the doctor that prescribed me Valtrex, which seems to help somewhat but does not totally get rid of the daily/ongoing symptoms. I also talked a couple times to Terri Warren who was very understanding but still seemed skeptical that I could have OH after all the negative results. If folks want me to post my full detailed story then I may get around to writing it. I would just like to say that I really appreciate people on this forum like Bob12 that are truly critical thinkers who refuse to accept faulty reasoning in the face of insurmountable evidence to the contrary. If not for them I would feel completely alone in the wilderness. Anyhow, another one for the record books.
  5. alexn

    Can flu affect Igg test?

    Hi all, If you have flu/cold (i.e. fever, coughing, sore throat) and you have an Igg test, is there a possibility of a false positive? I.e. can antibodies reacting to the flu affect the outcome of the Igg test (cross-reactivity?). If you do have to wait between having the flu and taking the test, how long should you wait for? Thanks
  6. Okay I will provide a brief back ground then would just like opinions or advice. I had been extremely ill with a bad head cold for about 3 weeks that antibiotics were not helping. Even now 5 weeks later I still wake up with mild throat pain. I started feeling burning in my vagina and automatically assumed this was a yeast infection as I have been with my daughters father for 9 years now and have had 0 other partners during this time. About 4 days after the original vaginal symptoms I noticed small white ulcers inside my Labia (looked exactly like a canker sore but on my vagina). I immediately went to gyno who told me that it was herpes and started me on valtrex. I had taken a fluconazole 2 days prior as I had assumed yeast infection. The next day my symptoms were gone and the Ulcers were practically healed as well. I don’t know if I can attribute this to fluconazole or valtrex. I had cultures done which were both negative, and igm which was negative both 1 and 2. Then an igg negative type 1 and positive type 2 at a 1.11. I was devastated to get a result 0.01 over being equivocal or negative. Also of note my partner got tested and he was negative for everything and has never had symptoms. So I believed I must have got this over 10 years ago when I was in high school and carried it this whole time and even had it when I had my daughter. I decided to go to my previous gyno (went to a new doctor first time as I had just moved). He ordered another hsv2 igg. And this one was NEGATIVE at a 0.84. I am conflicted as to what I should do. I did not think my “outbreak” looked like herpes personally, but I had an expert telling me it did. I was just so extremely sick. The second test was only 3 weeks after the first. This has been extremely emotionally exhausting for me. Especially as a mother because my mind was spinning thinking I could have hurt my child at birth or given it to her in her short life so far. My partner doesn’t think I need more testing and I am leaning toward just waiting till my next pregnancy and doing another blood test then. Is that crazy? Thanks
  7. Scenario, I had a sexual encounter with a person in early January, I was afraid of any STD did two weeks after i got a full panel test. All results, except HSV1 were negative (I've had HSV1 for a long time). I got tested again (independent anonymous lab) 5 weeks 4 days post exposure and this time the IGG results forHSV2 cane back as 1.03. Scared, the next week I went to my doctor AND to an anonymous lab (just for comparison). My Dr results were IGG 1.08 and other lab was 1.06. My doc said positive and I stated daily valtrex. Now, 12 weeks and 2 days after exposure, my HSV2 IGG is at .74. I've read a lot of conflicting information about this scenario... valtrex does affect blood work, valtrex doesn't affect bloodwork.. I've never had a "typical" outbreak, if at all. My first one, if that's even what it was, started with a folliculitis type rash in my pubic area, itchy scrotum, an increased urge to urinate, and an itchy feeling inside my urethra BUT NO TYPICAL LESIONS, like all the Dr's say will happen. I had a second possible ob, with the exact same symptoms a month later BUT NO LESIONS. It was just after clearing that I went to the doc. So my question is..... can valtrex LOWER an IGG score that much? I've read that Terri Warren (although I couldn't find the direct post) said that it can delay seroconversion BUT can it change the numbers so dramatically? I'm scared to stop the valtrex because of my situation, im married and had an affair with the other woman. My wife knows, everything, and we are working through things BUT I must need piece of mind.
  8. Hey there! I'm hoping you guys can help me sort this out, as I'm really frustrated at the moment. Apologies in advance for the novel! So the situation is this... Trying to be a responsible adult, I had my doctor order a full STD panel a few years ago. In Dec 2015 I tested positive on an IgG test for HSV-2. My value was >8.0. Had them retest me again a year later (again an IgG) and my value came back as "positive" again (with no number value - the test just either said positive or negative.) When I had these tests done I wasn't showing any symptoms and I didn't have any scrapings or cultures run. So it was just the IgG tests. The positive result came as a huge shock to me. And my doctor at the time never talked to me about the results. So I just assumed from that day onward that I had HSV-2 - and he prescribed me Valacylovir basically because I asked him to. (Because I'd read that's what one should take.) So what do you all think? Do I have HSV-2? I've been living with the impression since the IgG test - and the mental anguish - that I DO indeed have HSV-2. Her comments have made me feel like wanting to know my own medical status is asking too much and that I'm making too big a deal over potentially having herpes. Ok, so I just got a response from her (I wrote her a somewhat disgruntled letter last night.) She makes the distinction between "active" disease and "exposure." And that "you are not considered to have active disease until you have diagnosed lesions." Sounds like it's usually the other way around and the IgG test is done to confirm the swabs/culture. Anyway, she says she's following the CDC guidelines. But I think she's misunderstanding what the CDC guidelines are: CDC says: "Asymptomatic persons who receive a diagnosis of HSV-2 infection by type-specific serologic testing should receive the same counseling messages as persons with symptomatic infection. In addition, such persons should be educated about the clinical manifestations of genital herpes. Because nearly all HSV-2 infections are sexually acquired, the presence of type-specific HSV-2 antibody IMPLIES ANGONITAL INFECTION. Intermittent asymptomatic shedding occurs in persons with genital HSV-2 infection, even in those with longstanding or clinically silent infection. " I read that to say that, yes, I have it, despite being "clinically silent" (i.e. no lesions) and that I'm still contagious. I don't think she should be telling people that they don't have "active disease" when they're still ultimately contagious. Do you all agree with my conclusion? (And btw, I live in CA and apparently we have a law now that says you must disclose if you know you're positive. So it's even more important that I know for sure.) Thanks so much for your advice and feedback!!
  9. For those with questions related to IgM and IgG antibodies and the body’s immune responses here is an explanation an actual Herpes researcher himself (whose name I will not reveal) so new members are not stuck in the dark with explanations from unqualified members: IgM is produced upon primary exposure, but those wane and never come back. IgG is produced after what's called class switching, and appears late in the first response (at extremely low levels), then higher and higher levels upon each subsequent exposure. If there is no exposure for a long time, the levels of IgG drop and are not protective. The best example of this is the need for regular tetanus booster shots; if you are not exposed to tetanus toxin between boosters, the protective level of IgG produced from the vaccine drop to a non-productive level; the booster gives the immune system a reminder and gooses up the IgG level to be protective again. In the case of herpesviruses, if the virus remains latent for a very long time, whatever protective immune reaction you had to it can wane and no longer be protective when a OB now occurs. Bottom line: primary exposure to anything (vaccine, first time your seeing an infectious agent, allergen, etc.) will generate an IgM response. Those B cells that produced IgM will go into memory, where they will be available to respond to a second or subsequent exposure. If the same antigen is encountered again, genetic changes take place in those memory cells that allow them to switch to producing IgA, IgG, and/or IgE, all of which are more effective for a protective response. If the stimulus reappears (usually we're talking 6-8 week increments between exposures), the IgG/IgE/IgA response is boosted even more; essentially your immune system is being told that whatever this antigen is, you keep getting exposed to it and the previous level of protection was clearly not enough; we gotta do more. If the stimulus is cleared and not encountered again, eventually the level of protective antibodies will wane; it's a way for your body not to waste valuable energy resources on something it doesn't need. Hence the need for periodic booster shots; you remind your waning protective response that this agent needs a higher level of antibodies to be protected. By reintroducing your immune system to the antigen, you're telling your immune system to boost its IgG/IgA/IgE against it. The way this applies to herpes is that your first antibody response from primary exposure will ALWAYS be an IgM response. However, that it frequently overlooked because it can happen even in the absence of signs or symptoms. Each OB acts like a stimulation, leading to the class switch to IgG or IgA antibodies against the virus. Each measurement of the antibody level, though, is a snapshot in time; one cannot tell when or how stimulated the immune system was. One must follow the course of the antibody levels. If they are waning over time, then the infection has already passed and your body is winnowing out unneeded antibodies (and cells producing those antibodies). If the levels are waxing, then you were recently re=stimulated to produce antibodies. If the levels are staying the same, there's not much one can say except you've had, or are having, an immune stimulus.
  10. I had unprotected sex January 28 2017, 3 weeks later 21 of February I tested positive for Syphilis 1.16 primary Syphilis , on February 26 (4 weeks) I got the rest of the STDs test including clymidia, gonorrea, HIV (4tg gen combo test), and HerpeSelect 1 & 2: all negative, can I trust my test?, I’m planning on retesting on the 3 month mark, what are my chances that my tests will change ( it’s been almost 2 month without any symptoms) I now that it may take time to create antibodies but my body did produce the Syphilis ( all do they are different diseases) really fast and dint have to wait the 3 month mark as recommended .
  11. rgreen

    HSV1 Diagnosis & Igg

    Hi All, My recent HSV1 diagnosis was over a text from the Doctor. YEsterday I went into the office to see the full report. I have an IGG of 3.92 positive for HSV-1. Can someone she a light on what the number means? Does it signify a recent infection, the severity of it?
  12. Check_Twice

    Low Positive HSV-2

    About four months ago I decided to get a full panel STD test. I didn't have any symptoms or reason to get checked other than just wanting to. I went to Labcorp and got my blood drawn. A few days later I received the results, and to my horror I came back positive for HSV type 2 with an IGG score of 1.99. I was in complete shock when I saw the results. I started googling herpes since I knew next to nothing about it, and discovered that there was a chance that it could be a false positive. Anything under a 3.5 falls into a low positive zone where the test could be a false positive. The only way to know for sure was so send my blood off for a Western Blot test, which is 99% accurate. So I waited the three months that they recommend and then sent off for the test. The process was really easy. I just contacted Terri Warren at westover heights clinic and she helped me with everything! It was by far the longest three months of my life though. I got the results back today and I am NEGATIVE!!!!!!! If you are diagnosed but fall into that low positive zone, do yourself a favor and get the western blot. It isn't cheap but it is worth the peace of mind. This is a forever diagnosis.
  13. Hi everyone, I’ve been reading some conflicting opinions on the forum... Do you believe that HSV+ people with atypical symptoms are less likely to have detectable antibodies and therefore have false negative blood tests? I don’t see how that would be possible but would love to get your opinions. Also, please see my other post about the symptoms I’m having, I’d really appreciate any input. Thanks!
  14. Month 1 Negative (hsv 2) at 0.2 igg Month 2 Negative (hsv 1) at 0.7 igg Month 3 negative (hsv 1) at 0.48 igg Month 3 negative (hsv 2) at 0.2 igg Month 3 negative (hsv 1 and 2 igM combined) Month 4 negative (hsv 1) 0.54 Month 5 negative (hsv 1&2) Pcr cell swab inside urethra , had pain, no blisters , or lesions so thought pain could be a sign of shedding. Month 5 negative (hsv 1) 0.50 igG Month 6 [26 weeks] (hsv 1 and 2) both 0.05 done individually Done at 4 different clinics, seen 2 dermatologists, 6 different doctors , planned parent hood, sex infection doctor, every one points to no hsv including blood test and pcr swab. But why am I still having symptoms? One dermatologist said stress and anxiety. Doctor said irritants like soaps, and others say everything looks normal I know my body and it feels different, I see my penis and my buddy looks different as well. How is it possible that everthing began to happen 3 days after possible exposure. I cheated on my gf which I've yet to tell, I'm too embarrassd and ashamed , she kinda knows , she's not stupid. She's kinda hinted but I just deny deny deny. We haven't had sex which I would love to keep it that way till I know I'm std free. I regret everything , wish I could take it all back but I can't,
  15. Will the use of Antiviral meds affect IGG blood test results?
  16. It has been almost 2 months of hell with my ongoing symptoms which I’ve detsiled on past posts. This week I’m having very bad headaches, twitching, a bit shaky hands, tingling, tinnitus, etc. I have been tested 4 times, once at 2 weeks, 3 weeks, 4 and 5 weeks but all so far negative. I know many here like to say it’s not herpes but my symptoms remain and it is becoming too much. I am going to try get some AV medication (Acyclovir or Valtrex) and see if this helps with anything. My question is, if I take the AV meds will it impact the accuracy of IGG blood tests going forward?
  17. To have a clean slate after a break-up I decided to get tested for "All The Things." Perhaps curiosity has killed the cat.. I sorta expected the IgG to be positive, as my ex & other partners had HSV I, although I myself, tested Negative years ago and have NEVER had any sort of break-out. But, my IgG for HSV I was negative at .20, as was my IgG for HSV II negative at .11. But, my IgM came back positive at 1.13 (cut-off is 1.10). OMG!!! As bad as the IgM test is known to be, this *might* mean I just recently exposed and I haven't controverted yet, or a false positive? Which is more likely? I KNOW I have to wait forever to get another IgG at least 3-4 months from last exposure..and maybe even a WB. Killing me, as I am obsessive and now super stressed. Starting my dating life with a possible new disease is tragically ironic. So, I have a few potential recent exposures and I am trying to play the "who done it" game and "how much risk" game. I have read here that IgM can be positive and the IgG negative when you have *just* gotten exposure (like with in 3 weeks)..so lovely...I was with a new woman once 4 1/2 weeks before my tests (making out/"petting", no oral). She states that she has never had an outbreak, nor her now ex-husband of 20 something years & believes herself to be negative. I was also with my on/off now ex-gf of 6 months the last time 6 1/2 weeks before my tests. She got her own test earlier this year after I mentioned that HSV is not part of a standard STD panel & hers came back positive for HSV I & started taking L-Lysine. She has never had a known outbreak of any kind-and was as shocked as I am now. HOW likely is it that my IgM is false with the time frame above? Is there a rate for false positives when the IgG is also negative? How accurate is the IgG at this point? How likely is it that my recent partner (from a month before testing) is why I have the positive IgM/negative IgG? How likely is it that I would pick up HSV from a person with no known breakouts and also have none of my own? I have had no recent fevers, no swollen lymph's either. I am also 46, for what it is worth. (Meaning I have likely had mono & certainly chicken pox) I will say that in early June I had a small, small area of slightly dry skin on my lip. Chapstick cleared it up in less than two days. I noticed it because I was wondering if it would grow into something worse, it didn't..that doesn't exactly scream "HSV' to me. Very stressed. Wishing I had not gotten tested. Advice is helpful.
  18. idontevenknowwhattoput01

    Very Confused with Results

    I deleted my other forum posts out of embarrassment. I was not accepting of this diagnosis whatsoever. To make a long story short, I went to the gynecologist on February 28 for an IUD. I decided I didn't want one, but went to the appointment anyway. The nurse practitioner looked down there and noticed a little paper cut or two. I have a connective tissue disorder and my skin everywhere is very fragile and can tear easily. I also wipe myself pretty roughly when I go to the bathroom. She said she was almost positive it wasn't herpes, but took a culture anyway and told me to get blood drawn. Mind you, I had the culture taken at about 4:30 PM and got called with results the next day at 12:00 noon. I came back positive with Genital HSV1. I thought it was suspiciously quick. I asked the nurse practitioner if false positive results ever happen, and she shut be down by just saying "no" with no explanation. I got my blood drawn that day. About five days later, I got a call saying my IgG was negative for HSV1 and HSV2. My result was <0.90 for both. Before my herpes blood test, I had sex with a guy once on November 11, making it 15 weeks + 5 days in advance to testing. The only guy I had sex with since was my boyfriend. I got prescribed Valtrex. The couple cuts I had went away, but I think it was a coincidence. A couple of days after being off the Valtrex, they came back in the exact same couple spots. I immediately told my boyfriend. I told him he needed to get his IgG tested. He got results a few days later. I assumed I had herpes from him. He called me with his results and to my surprise, he was negative. We were both very happy to hear he was negative. A couple weeks later, I went to urgent care (this Tuesday) for an unrelated issue and ended up explaining my situation to the super nice physician assistant. She asked me if I wanted her to look down there. I said yes. She said "I see what you're talking about, but it doesn't look like herpes to me. I will culture it for you." She took an IgM blood test too. I also have a few little dark pigmentation spots down there. I had one, but I have quite a few more all of the sudden. She said I almost look like I have lichen sclerosus. I informed her how quickly I got the first culture results back, and she said that is unheard of. Yesterday, I decided to call urgent care to ask if they got my results. They just got them in. I was so nervous and shaking. The culture was done in three days (much more believable) and was negative. The IgM was negative for HSV1 and HSV2. What I'm confused about is how I got a false positive initially? I know medical errors happen... I did a lot of research and came across an article where a woman was awarded $2,500,000 for an HIV misdiagnosis... Any insight would be helpful, and stories appreciated if this has happened to anyone else!
  19. A technical question for those who might know, does the standard IGG and IGM HSV1 and HSV2 blood testing detect the various strains of each? I know these tests actually detect the antibodies and not the virus but would the antibodies be different if the strain was different?
  20. Month 1 negative hsv2 igg Month 2 and 3 negative hsv 1 and 2 igg Month 4 negative hsv 1 and 2 igg Month 5 negative hsv off Month 5 negative pcr cell swab inside and outside urethra. Most painful experience ever. How accurate are these pcr cell swab tests? Since I have no so sores or blisters that they could swab I went when I thought I would have an outbreak, which was when I was having urethral pain and inflammation and nerve pain all around , I went to get it swabbed. Kinda took some skin off, still painful. Asking since my symptoms don't go away. Could it all be in my head. I had protected sex and oral, probably lasted 5 minutes. But these symptoms came after 3 days of possible exposure.
  21. On June 16 I may or may have gotten hsv because of a poor choice I made. 2 days after the decision I made in began to worry and thought, hey I might have caught HIV. I beagn feelingn symptoms and our dear friend Google was my daily symptom checker till this day. I had protected oral for about 2 minutes and penetration was protected as well for about 4 minutes. My results as of now. 4 weeks hsv 2 igg 0.2 negative 8 weeks hsv 2 igg negative no index value 12 weeks in hsv 2 igg negative no index value At this point I just thought about hsv 2 and didn't realize about the possibility of ghsv1. So then I got that done. 15 weeks in hsv 1 0.7 negative and hsv 2 0.22 negative 19 weeks in which is present today Hsv 1 0.48 and hsv 2 still at 0.2 I've read that a single protected encounter is a possibility but a rare one , given my results I know I should feel better, but I don't. I think I have herpes symptoms but without the lesions , blisters or sores. I have nerve pain but I can attribute it to something else. Does the index numbers matter if it's actually going down? I haven't taken any type of antiviral during all these test. Thanks.
  22. Herpes is on the rise, folks... Herpes Marker Testing Market to Reach US $481.8 Million by 2025 October 23, 2017 Global Market Study on Herpes Marker Testing: Antibody/Antigen Based Kits to be the Most Attractive Segment by Test Type During the Forecast Period 2017 – 2025 https://globenewswire.com/news-release/2017/10/23/1151484/0/en/Herpes-Marker-Testing-Market-to-Reach-US-481-8-Mn-by-2025-Persistence-Market-Research.html
  23. snookems

    Newly Diagnosed

    I recently tested positive for HSV type II. Does anyone know what it means to have high IgG levels? Some sites say it means it has been contracted a while ago while others say everyone's anatomy is different so it cannot determine an estimate as to how long its been dormant in my system.
  24. Hi so I have some questions over my test results I received last week. I get tested regularly for all stds, including herpes. I was last tested in October and my blood test came back clear. Fast forward to now, I recently had sex one time without a condom about a month ago. That same day I had a fever, the fever lasted on and off til the weekend after and I have not been intimate since. At that point I also noticed some soreness- discovered ONE small bump on my labia that I have never experienced before. I picked at it (thought it was a pimple) and it started go away as did my fever. That area started burning and stinging to the point where it was uncomfortable to walk or sit a few days after so I did as my OB told me and went in to get checked. I got the lesion tested and the results came back positive for hsv2. I also got my blood tested both IGM & IGG. Both were positive for hsv2 (IGM-3.8) (IGG-5.4 hsv2) (IGG-.21 hsv1) I asked my doctor what that meant and she said that I was previously infected but also have a current infection which was the lesion. I told her I had previously been tested in October and was fine and that one bump is the only outbreak so I'm not sure when I could've been infected and she said that she thought because I had sex and then a week after that showed up that my results could just be reading this way because I have a current outbreak and more than likely it was from the one encounter I had. After reading up on these tests I'm not sure what to think. Would my IGG test show up positive only a week and a half after having unprotected sex with someone who is infected one time? I read that these results usually take 3-6 months to show up on an IGG. I also read that IGM results are inaccurate. I'm really new to this and am just trying to figure out how long I might have had this and whether or not I need to tell my ex who I was with a few months beforehand if there's a chance it might've been from him although I was with him when I last got tested in October. There is just a lot I don't know, Since this is my first outbreak should I get re tested in 6 months? Or does it even matter? I am also trying to figure out how often I should take valtrex. Should I wait to see if I have another outbreak since I only had that one bump or should I get the daily medication and just not take it everyday if I am not sexually active? thank you in advance!
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