Unlike anyone on this board they have decades of combined experience dealing with this virus and I feel confident they have thought this through very thoroughly. Do you think they would go to a National Conference in Boston and not have thought through these obvious concerns? Like I said before, Dr. Bloom chose to study vector delivery years ago when he won the 50k HSV Pepsi challenge instead of chasing vaccines and the like which upset a lot of people on this board. He was looking long term and here it comes! There's your hope! rAAVs have many variations and these guys are no dummies....read their peer reviewed articles and follow their logic!