Jump to content
World's Largest Herpes Support Group
Sign in to follow this  
itsover

High doses of Acyclovir better?

Recommended Posts

itsover

For my last outbreak (when I also insured) I was RXed fifty 500mg Valtrex pills. The directions said take 3 a day. I took 2 in the morning and 2 at night, treatment last approximately one week. It retreated wonderfully and did not get so much as a sign of an outbreak for four months.

November 30th I noticed a lone small raised red bump on the shaft of my penis, I had to wait 30 hours until I could get medicine. The medication I was RXed this time was generic Acyclovir 200mg x 30 (Walmart has a deal on this particular dosage at only $4) capsules to take 3x a day.

I read that Acyclovir has a low bioavailability (around 10-20%). So if I'm taking one 200mg capsule that means I'm only getting 20-40mg in my bloodstream to fight the virus. That's not very much active drug, is it?

So my question is if I take 800mg 2x a day will is that better than just three 200mg 3x a day? I figure that taking 800mg gets much more in my bloodstream... or am I wrong and only so much is absorbed?

Also, does taking mega doses such as these kill the infection and make the virus go into latency for longer periods of time?

Share this post


Link to post
Share on other sites
Sincere25

Well i also got Acyclovir but 400mg tabs x 30 from Walmart at 8 dollars. Im poppin 3 in the morning and 3 at night. "More than the recommended dosage" im also hopin this bullcrap goes into latency or asymptomatic state cause ever since findin out in June 08 that I have it, I been gettin bi weekly outbreaks until the beggining of November when I started to take Acyclovir, I went a week without takin it and on thanksgiving "last thursday" had another outbreak, so I went and got another set of pills and now its clearing up. I been under a lot of stress lately and ate some peanuts.

Share this post


Link to post
Share on other sites
itsover

Sorry to hear about your frequent outbreaks. I think when the virus comes out of hiding, blast it immedidately with high doses (800mg Acyclovir 2-3x a day or 1g valtrex 2x a day), and tapering down to half that after a few days. It really seems to knock the wind out of the virus (for me at least) and it completely goes away.

And if this current outbreak (small raised lesion that has not ruptured, or grown) is anything concerning the current state of my infection, it's downright pathetic compared to the outbreaks I was getting (started off as red patch size of thumbnail, entire red area filled with blisters and it gelled into one scab and then spread even more).

I believe high doses of antivirals when the whack-a-mole herpes virus comes out is the best option. Really kick the shit out of it. Seriously.

Don't listen to doctors who want you to to maintaince therapy. I think it is useless and only has the risk of making you immune to the medication, and possibly strengenthing the virus to the small amounts of ACYCLOVIR coming in.

Share this post


Link to post
Share on other sites
itsover

Just to clarify, I meant the virus goes into longterm latent hiding. In my case it was four months after having tri-weekly outbreak episodes. The entire point is to weaken the virus as much as you can when it's out doing its dirty work.

Any thoughts?

Share this post


Link to post
Share on other sites
itsover

Well, the outbreak has been healing and I've been taking 800mg Acyclovir 4 times a day. High dose, but better safe than sorry.

Acyclovir has such a poor bioavailabillity.

Share this post


Link to post
Share on other sites
itsover

bump. Literally. I still have a bump. Why won't it go away? The outbreak has been arrested.

Share this post


Link to post
Share on other sites
itsover

bump again. No comments on this?

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
Sign in to follow this  

  • The Hive is Thriving!

    • Total Topics
      69,296
    • Total Posts
      466,185
  • Posts

    • MikeHerp
      The prophylactic vaccine trial by GSK took 8 years and they were still not done with it.  That's because it takes time to see whether it works--it's a matter of many people having sex over time and that just takes a lot of time.   A shedding study is quicker, so therapeutic vaccines are quicker to test.  5-6 years I think.  Note that there was a study conducted last year that showed that there's a high correlation between shedding and outbreaks, suggesting that it might not even be necessary to track outbreaks, measuring shedding may be enough. It's unclear what they would be proving in case of a gene editing technique.  I think shedding would be a part of it.  But what else, if anything, I don't know. Anyway, it doesn't necessarily have to take a long time like the GSK prophylactic trials.  
    • Miss Horne
      Role play? Dressing up in the bedroom?
    • Voyager2
      I certainly hope this research continues. It all seems legit to me, but again, I'm no medical man (although I did play doctor a few times).   
    • here-to-help
      This is good information to know. To go from continuous outbreaks to none all this time is encouraging. I wonder if after you've given it some time and this regimen proves itself, maybe you could title it, and type it for everyone to read. The more suggestions, the better! You mentioned you've suffered with Herpes I outbreaks. I have suffered with the type II, and I recently read that Lysine doesn't help with the type II. I don't know about that, because it really has helped me in years past. Anyway, by mentioning in your article that you have type I will help, because apparently something might work for type I that won't work for type II. I myself will get these products and add them to my daily garlic regimen, and perhaps I will be able to eat whatever I choose without triggering an outbreak. That's my big problem, wanting to eat the foods that trigger the outbreak!
    • RNY18
      “..Meanwhile, the present study suggests LDXGFG as an alternative, inexpensive, and lasting-effect medicine for curing HSV2 infection caused genital herpes....” Anyone  seen any further research on this ?
×

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.