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curecomingverysoon

Boehringer Ingelheim primase-helicase inhibitor in development?

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curecomingverysoon

BILS 179 BS and BILS 45 BS... but nothing since 2004...haven't been able to find a thing! I find this very odd/mysterious considering how positive the results were and how much money Boehringer has!

I find it hard to believe that it was just dropped?

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T2H-4C5VMKJ-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=f0ac118aff69142330faa42a9ceb6368

http://aac.asm.org/cgi/content/abstract/47/6/1798

http://hum-molgen.org/NewsGen/04-2002/000011.html

http://www.nature.com/nm/journal/v8/n4/abs/nm0402-386.html

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Herpes Awareness

I have received info from Boehringer Ingelheim that they are not actively developing their BILS HPI compound for HSV, choosing to look at Hep C antivirals instead as a priority. I received this info maybe 6 months ago.

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curecomingverysoon

How disappointing! I guess it's on Astellas and Aicuris to pull through for us.

I'm actually surprised, considering the relatively low incidence of HCV and how positive the indications for BI's HPIs were...

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Herpes Awareness
How disappointing! I guess it's on Astellas and Aicuris to pull through for us.

I'm actually surprised, considering the relatively low incidence of HCV and how positive the indications for BI's HPIs were...

I rechecked the email, and they mentioned focussing on HCV and HIV in future. The difference is that HCV causes death in about 20 years for sufferers, whereas HSV is mainly a nuisance infection. HIV obviously causes death as well. The medical fraternity in general have trivialised HSV for a long time in terms of effects, as it is generally non-fatal -- they don't really care about the relationship-forming or psychological consequences, until 25% of the US population is infected and starts screaming for a cure...

I note that the recent Bayer study included the BILS compound, so they clearly have access to it, and may well be considering purchasing the right to use the compound if BIL aren't interested in working with it...

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