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curecomingverysoon

PowderMed HSV2 Therapeutic Vaccine Unsuccessful in Phase I

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curecomingverysoon

I wrote to Pfizer (which bought PowderMed) inquiring about their HSV2 vaccine a few weeks ago and received the following reply from a member of the Vaccines Research Unit:

The PowderMed HSV2 vaccine has completed PhI clinical trials for the treatment of genital herpes infections. The immune responses obtained from vaccinating healthy volunteers did not produce immune responses of sufficient magnitude to progress into PhII. We continue to work on improving the DNA vaccine technology and envisage its application to a genital herpes vaccine once this has been achieved. Like you, we recognize the importance of a genital herpes vaccine and are exploring alternative antigen delivery technologies in parallel to the PowderMed technology to improve the likelihood of success.

Thank you again for your enquiry.

Very sad but it seems like they're still working on HSV-2.

For those interested, here was the 2004 press release: http://www.powdermed.com/pdf/HSV2_and_HIV_Therapeutic_Vaccines_enter_the_clinic_12_October_2004.pdf

and also an article:

http://www.bioportfolio.com/news/PowderMed_3.htm

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