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What really triggers OB's???

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Hello, Im new to this forum. My husband gave me herpes when we were dating about 20 years ago. He doesn't really get OB's so he said he didn't know....that's questionable.

Anyway, he has had outbreaks but in the 20 years we have been together maybe 5 at the most. However, I'm plagued with intermittent OB's --even during my pregnancy (almost had to have a c-section).

My question is: Are OB's directly related to the immune system or perhaps hormones? Not as many men have frequent OB's as women and the women all have outbreaks that seem to directly correlate with their monthly cycles (myself included, by all means). I feel like I have a good immune system--I don't get sick very often and with 2 kids I'm exposed to everything. So, I won't get sick but I'll get an outbreak...???

Also, do you think OB's have something to do with anxiety? I have anxiety and mild depression and a basic dissatisfaction with my life in general I don't take antidepressants but I regularly exercise, take all the supplements I need, eat organic, etc. Do others suffer with anxiety/depression and frequent OB's? Is there a connection between the two?

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Scientists find fever is the most reliable way to trigger herpes OBs in lab animals. UV light it pretty widely believed to trigger it as well, beyond that who knows.

There are many conflicting theories of why some people get many outbreaks and some get few/none.

One recent theory is that it is just random chance, a certain protein the virus needs to cause outbreaks (VP16) simply does not get transported to the nerve cell during infection in some people causing them to be asymptomatic.

Other research points to the immune system's CD8 cells (T-Cells) as playing a key role in preventing outbreaks, so naturally a drop in CD8 production or a poor level of CD8s would cause outbreaks. Even if one did not have HIV or a PID one could have a temporary drop or naturally low-normal production of T-cells.

Another study has shown that people may have a genetic predisposition to getting outbreaks. This may or may not be related to optimal immune function. The researchers have identified several genes which they think may be involved but further study is needed to determine what if any role these play.

Outbreaks could be caused by any of these, all, or none. Really at this point its just not well understood. Unfortunately neither is depression, so you probably shouldn't expect a satisfactory answer.

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Try a Lysine supplement for cold sores

  • The Hive is Thriving!

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    • Carguy
      I wish you luck my friend! It’d be nice to find something! The only two things I’ve ever tested positive for during this whole mess was a fungal infection in the groin creases, found by biopsy, and the nerve biopsy found nerve damage. I just hate thinking I’m unluncky enough to have HSV1 which is suppose to be the most tame where supposedly people have few if any problems with it, and mine have been endless! Do you have extremely sweaty scrotum and inner thighs when you wake up and periodically throughout the day? That’s been driving me nuts!
    • Thomas29
      This was about 10 mins ago I tried squeezing it to see if anything came out of it, it also didn’t hurt sorry for the pics I am also on my period so it isn’t going to be nice, I’m sorry for this !:(
    • Thomas29
      Pic of half hour ago 
    • Thomas29
      Sorry to bombard your post hun but I’ve got a cut too on my vagina (labia) I shaved the night previous and the next day I had an itch so I itched with but I didn’t put my hand down their I used my knickers and all of a sudden I felt an irratation so I went to go have a look and I found this, it doesn’t hurt when touched and doesn’t hurt when I pee I can sit around and stuff, is this the same thing as yours? I’m going insane right now I’ve got health anxiety I want to cry thinking I have herpes 1st pic is what it was like when I looked first  2nd pic is when I got out the shower  3rd pic is now  and 4th pic is when I tried squeezing it to see if anything came out of it ( it never hurt either)  After shower pic 
    • Peonyrose
      That is exactly what mine look like (on one side of labia anyway) and the rest are kind of dark red flat pimple bumps 

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