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Guest Healing09

I really need your feedback. Please.

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Guest Healing09

On October 12 I started having symptoms of the worse yeast infection that I had ever experienced. Due to work and everything, I did not get to the doctor until October 22 at which time my doctor did a swab test. From October 18th through the 22nd things got progressively worse, and I started having pain in my vagina and the paper cut feeling. It was the absolute worse paid I had ever felt in my life. I felt like I could not close my legs. My vagina was very red and swollen. I had discharge and small white bumps on the inside of my vagina. On October 29th (by this time no symptoms or pain), I got a call back from the doctor that my test was positive for genital herpes. I went back to the doctor on Nov 4th and requested a blood test. The results of the blood test came back 2 days later as Positve for IgG and Negative for IgM. Based on the results, my doctor said that it appeared that I have been carrying the disease for "some time." I was so frustrated. I was hoping that the blood test could help me determin where I got this from. I had not had sex since 2001 until April 2009 through July 2009 with my current boyfriend. I have received and given oral sex from April '09 through October '09, but have no cold sores or anything unusual. My boyfriend and I have not had intercourse since July 2009, but in addition to oral sex, we have had genital contact.

My question is could I have been carrying this disease around since 2001 or earlier without any symptoms? Or did I get it from my current boyfriend? Also, as of today, it feels like I am getting symptoms again - discharge and the tinggling. I just want to make sense of all of this.

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phenomenalandloving

i thought antibodies in your igm test indicated a past infection. igg indicated recent infections?

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hhasthehblues

Theoretically, it's the opposite, however it's inconsistent and can't be used to indicate when you were infected for sure.

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phenomenalandloving

wait. so igm indicates recent? and igg indicates past?

please clarify in full sentence.

thank you.

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totalregret

phen,

Check this out:

http://www.ashastd.org/phpbb/viewtopic.php?t=4182

, Sep 20, 2006 12:00AM

You're right, this has all been addressed several times. However, it's in many places and might be hard to dig out. So I appreciate the opportunity to put it all in one place.

In theory, the body produces immunoglobulin M (IgM) antibodies first, to a variety of infections, and immunoglobuin G (IgG) antibodies later. Over time, IgM antibodies tend to stop being produced entirely. Therefore, a test for IgM antibody to any particular infection may be positive before a test that detects IgG antibody. And in a person infected a long time previously, IgM antibody is absent but IgG persists.

That's the theory. In general, it holds up pretty well in young children, but sometimes not so well in adults. In adults with new HSV infection, IgM antibody against the virus doesn't actually get produced all that much faster than IgG antibody. And many people with longstanding HSV-1 or HSV-2 infection continue to produce IgM, especially when they have a new symptomatic outbreak. Thus, for HSV, IgM doesn't necessarily mean a new infection; and absence of IgM doesn't necessarily mean a longstanding infection.

On top of that, there are 2 other main problems with IgM testing for HSV. First, false positive tests are common--that is, apparent IgM antibody that simply isn't present at all, despite what the test says. This is NOT generally due to cross reaction with related viruses, i.e. HSV-1, varicella (herpes) zoster, and the like. It has to do mostly with the physical chemistry of the test.

Second, there are no type-specific IgM tests on the market--nary a one. Any true-positive IgM test for HSV is detecting antibody to HSV-1, HSV-2, or both, and can never distinguish between them.

Why do labs continue to offer such a lousy test? Several reasons there too, some reasonable, some not. Some providers still request the test; they were taught the theory, they assume it applies accurate to HSV, and don't understand the limitations of the test. (The pediatricians generally are right; IgM testing for HSV in fact remains useful in diagnosing neonatal herpes in newborns. Their immature immune systems don't crank out IgG so rapidly.) Also, some labs just keep offering the test out of habit, in the belief the providers want the test; while at the same time, the docs just assume that if the lab does the test, it must be worthwhile. (That is, a communication issue.) Also, there is simple profit motive for labs: IgM testing is very cheap but gets good pay-off from insurance companies, so the profit margin is high.

Bottom lines: Sometimes a new HSV infection in an adult indeed will be positive by IgM before IgG. But this is pretty infrequent, and it outweighed by the downsides: high risk of false positive result; and even when truly positive, there is no distinction between HSV-1 and HSV-2, which is pretty important to most patients and providers.

_________________

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    • Jayne
      I know this thread is a couple of years old, but it’s been helpful to me, and I wanted to contribute as well. Back to Berliner’s original post, I’ve tested negative on several IGGs, with the latest ones being 1 yr and now almost 2 years past exposure.  Figuring out what was going on was the worst nightmare I’ve ever been through in my life. I made the mistake of drinking heavily a week after my father died of cancer, and I had unprotected AS with an ex, who happened to be poly and had some occasional unprotected M2M encounters.   Three days later I had a red line rash along my (sorry to get explicit) crack. This was followed by a rectal burning. Tested negative for G&C and related tests.  Over the next couple of weeks I had severe swelling and discomfort in my lower right quadrant and was told to go to the ER, where (I guess as a standard practice) they did a cat scan, which revealed nothing.  Also not a bacterial infection.  However the repeated manual examinations that occurred at urgent care and the ER seemed to relieve the abdominal pressure over the next few days.  I then had diarrhea for the next several weeks after.  I developed what felt like internal hemorrhoids, which were exacerbated by the diarrhea, and a gastro doctor confirmed via digital exam that there was indeed some sort of mass that felt like possible hemorrhoids. He ordered a sigmoidoscopy, but by the time it was undertaken, whatever was there was gone. After the procedure though, I felt much better for a while, possibly due to digestive issues clearing up after the colon “cleanse.” But this was concurrent with other issues.   About 3 weeks after the encounter I developed a large rash on my left thigh. Shortly thereafter I started having light sensitivity issues, culminating in a fever-like state after being outside in the sun only for 15 minutes after work. At work around that time for a couple days I felt like I was going through life encased in a gauzy gel- similar to being on laughing gas at the dentist, but not in a good way. I didn’t know what the hell was happening to me. I developed a severe case of canker sores for about a day. Later during a sunny drive, after getting back in the car at a gas station I noticed a red blotch below my lip. I tried to shrug it off but it happened again on the trip back.  So by about a month after the encounter I was having more anxiety. I spent the night at a friend’s house and woke up with a massive, swollen red eye and swollen lips. I got eye drops for bacterial conjunctivitis but that was wishful thinking.  A couple of weeks later, my lips were covered in sores. I smothered them with abreva. By the next day, they had mostly gone away. I tried to do a swab test at urgent care (I believe it was the next day), but there was not enough there to make any sort of positive diagnosis. Since then, I’ve had what you could call repeated aborted lesions and red blotches that appear around my mouth, particularly after stress and alcohol consumption. But even having peanut butter or chocolate would set it off for a long time. Fair skin doesn’t help- there was no hiding it. Two months after the encounter, I had my first vaginal burning- it was pretty intense and I had to use ice cubes because I didn’t know what else to do.   The worse feeling though was the periodic flare-ups of rectal itching/burning, often accompanied by another red line rash. It made sitting uncomfortable for about the next two months. I couldn’t wear pants at work- only skirts seemed to make things somewhat less irritated. And for the first three months, I was still testing for HIV along with HSV because of the overlapping symptoms (rash, diarrhea, neural pain, severe flu like symptoms without fever). I lost a lot of weight and had panic attacks. On top of all this I had just moved to a new city and started a new job and didn’t have a support network. And the sad thing is, I had to deal with all of this instead of being able to grieve for my father and being a better source of support to my mother. She had to support me without understanding what was happening.   Another bad thing through all of this was having both my ex and my current partner treat me like I’m crazy. That makes me feel alone and in the dark. Another “hysterical woman.” F*** that.  And while I felt grateful that my current was at the time still ready to be with me even if I had hsv, it’s a little discomfiting that he still doesn’t really believe me. But I’ve learned to live with ambiguity. And now I’m used to doctors as well as partners acting like this is nonexistent. Especially with negative IGG tests even 2 years later, which have left me without any answers.  I’m lucky in a way to be able to blend in because I don’t get obvious sores, genitally or orally (I can cover up the blotches with concealer, and they fortunately have lessened in frequency). But I still get the rectal itching/burning every six months or so (anthistamines seem to alleviate it a bit). And as more of a concern, I’ve had a cramp in my lower right quadrant ever since, which feels like it’s in my digestive tract. Since this has pretty much spread everywhere else in my body, intestinal involvement wouldn’t surprise me, and it isn’t unheard of anyways. I’ve tried to move past this and have since gotten married to my partner, who is a source of support (even if he doesn’t believe I’m having health problems. I know that’s a contradiction but occasionally I want to believe that too.).  I’m also newly pregnant, and symptoms have started to flare up again somewhat. I’m sure this will be an adventure. Hopefully more good than crazy. I know I’m going to struggle with the fear of passing this along but I’m trying to reconcile what doctors say (which is that it is extremely rare) with my own intuition about what I need to be careful of. Maybe I’ll repost with an update down the road. In short, there are people out there who test negative and have to live with loved ones and doctors thinking that a negative test closes the book on this. Again, learning to live with ambiguity is a real life lesson that I’m still coming to grips with. This forum and specifically this post have been a source of comfort that I haven’t been able to find elsewhere. Thanks everyone for the support for the community.     
    • Rockster
      You deepthroat so good that you get all kinds of mouth-to-skin-of-base contact? Kudos to you, but that is extremely rare. 
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