How protein interacts from Sciencedaily

[Kqk]

http://www.sciencedaily.com/releases/2011/01/110106192027.htm

This shows how they can see proteins from HSV interact with human cell proteins. This was reported yesterday on www.sciencedaily.com . Click on that latter portion of the link to read this article.

Sanner

[dinki]

did u see this article too?

http://www.sciencedaily.com/releases/2009/03/090323112058.htm

[Kqk]

Did you see this too?

Yes, I saw that when it came out in 2009. I am on sciencdaily.com every day to check out hopeful stories.

[Kqk]

Another one

Here is another article where they are working with the herpesvirus that causes Epstein-Barr. If you read the article, they show how the virus disables the immune system to begin infecting cells.

http://www.sciencedaily.com/releases/2011/01/110105091142.htm

After these two articles, I believe the science community is taking HSV seriously. Thank you to everyone who has donated and tooted your horn!!!

Sanner

[url=http://www.sciencedaily.com/releases/2011/01/110105091142.htm]

[struggle83]

The most interesting item in this article is:

The 3-D model shows how the viral protein piggybacks onto the molecular machinery components inside human cells, promoting virus replication and spread of infection through the body.

That is a critical piece of information. If you ask your doc they will tell you HSV doesn't spread around the body. You can now tell them that that is garbage and you now have science to prove it. I've been espousing for months that there is no reason for this virus to settle into your ganglia and just stop there. It has the keys to the castle. It doesn't make evolutionary sense for it to do that.

My opinion -> Let's face facts, viruses are no friends of ours. They kill people every day. Ours may not kill at an expedited rate like HIV or Ebola but make no mistake, it intends to damage us, some mortally.

[Kqk]

I'm posting this because they have found a protein that unzips MRSA so that it can infect cells. I hope they find the protien that unzips the outer shell of the HSV virus

http://www.sciencedaily.com/releases/2011/01/110116144436.htm

I think all the things they are doing on a molecular and cellular level is very fascinating.

Sanner

[struggle83]

I'm posting this because they have found a protein that unzips MRSA so that it can infect cells. I hope they find the protien that unzips the outer shell of the HSV virus

http://www.sciencedaily.com/releases/2011/01/110116144436.htm

I think all the things they are doing on a molecular and cellular level is very fascinating.

Sanner

Actually, the lipid coating from the herpes virion is "unzipped" by certain fats. Check out information on coconut oil and the fats in it that are antiviral. The virions aren't the challenge, it's removing the viral DNA from the human DNA in infected neurons that's the challenge.

[Herpes Awareness]

The most interesting item in this article is:

That is a critical piece of information. If you ask your doc they will tell you HSV doesn't spread around the body. You can now tell them that that is garbage and you now have science to prove it. I've been espousing for months that there is no reason for this virus to settle into your ganglia and just stop there. It has the keys to the castle. It doesn't make evolutionary sense for it to do that.

Don't get too carried away with one ambiguous sentence in a pop science article. All viruses tend to infect one cell type only, and often in one location. Cold viruses go for the throat and nasal passages, HIV goes for certain types of T-cell, EBV infects your B-cells, HSV your nerve cells, Hep C the liver, etc etc. The fact is that these things only seem to invade via mucous membranes of the lips and genitalia, and take up residence in the spine and nowhere else much. You don't see it breaking out all over the place, with the exception of herpes whitlow, herpes gladiatorum, etc -- the easiest path is not normal skin, though.

My opinion -> Let's face facts, viruses are no friends of ours. They kill people every day. Ours may not kill at an expedited rate like HIV or Ebola but make no mistake, it intends to damage us, some mortally.

Of course they're no friends. I don't think there's a single benign or helpful one out there that will improve your quality of life. But the most 'successful' virus doesn't kill its host, because then the virus dies with it -- instead, it sets up an uneasy coexistence and figures out how to retransmit itself to another host...

[camomile]

Here is another article where they are working with the herpesvirus that causes Epstein-Barr.

After these two articles, I believe the science community is taking HSV seriously. Thank you to everyone who has donated and tooted your horn!!!

EB has been on top of the virus league table for some time.

Which donation are you referring to?

xx

[camomile]

Actually, the lipid coating from the herpes virion is "unzipped" by certain fats. Check out information on coconut oil and the fats in it that are antiviral. The virions aren't the challenge, it's removing the viral DNA from the human DNA in infected neurons that's the challenge.

Do you eat coconut oil? I do understand coconut oil is H trigger?

One question, does shingle vaccine disarm its virus to be effective in a similar action H vaccine ought to be? If it already worked with shingles, why H vac can't be done pretty much in the same way?

[struggle83]

Of course they're no friends. I don't think there's a single benign or helpful one out there that will improve your quality of life. But the most 'successful' virus doesn't kill its host, because then the virus dies with it -- instead, it sets up an uneasy coexistence and figures out how to retransmit itself to another host...

I have to disagree with that last statement. This virus doesn't have a "plan" with respect to the host. It doesn't have intelligence or even a metabolism. Viruses have no evolutionary strategy so they don't care if they kill the host in 20 days or cause irreparable damage over a whole lifetime. The ones that kill quickly come and go but they can still continue to exist (ie flu viruses like the black plague are still around today). Look at HIV, it used to kill within a few years but it spread like mad. Virus existence is a very complex thing. Scientists are still trying to figure out where viruses came from and what evolutionary role they play. Just my opinion. Not intended to flame. It's an interesting topic.

[struggle83]

Do you eat coconut oil? I do understand coconut oil is H trigger?

One question, does shingle vaccine disarm its virus to be effective in a similar action H vaccine ought to be? If it already worked with shingles, why H vac can't be done pretty much in the same way?

I was eating cocomut oil daily. I stopped when I started the beta glucan.

[SuperManFace]

I have to disagree with that last statement. This virus doesn't have a "plan" with respect to the host.

You have a point here, as long as a virus infects more hosts (even if slightly more) than kills, it will have no reason to evolve any further to prevent extinction.

It doesn't have intelligence or even a metabolism.

Define intelligence, because this is still debated among even the most reputable experts on intelligence.

Look at HIV, it used to kill within a few years but it spread like mad.

Not exactly. HIV infection has remained stable and has stayed within the risk group which BTW is quite unheard of in infectious diseases, which start in the risk group, and then eventually spread throughout the whole population.

[SuperManFace]

I was eating cocomut oil daily. I stopped when I started the beta glucan.

So it didn't work at all for you I take it?

[SuperManFace]

Actually, the lipid coating from the herpes virion is "unzipped" by certain fats. Check out information on coconut oil and the fats in it that are antiviral. The virions aren't the challenge, it's removing the viral DNA from the human DNA in infected neurons that's the challenge.

Removing the viral DNA from the human DNA in infected neurons would be monumental and probably an unnecessary overcomplicated task. The best thing to do would be to kill all HSV containing cells, preferably by stimulating your immune system into doing that. Our immune system is better equipped for the job, gene and cell therapy proves this. It has all the necessary tools to get it done and will always do it better. It just has to be persuaded.

[struggle83]

You have a point here, as long as a virus infects more hosts (even if slightly more) than kills, it will have no reason to evolve any further to prevent extinction.

Define intelligence, because this is still debated among even the most reputable experts on intelligence.

Not exactly. HIV infection has remained stable and has stayed within the risk group which BTW is quite unheard of in infectious diseases, which start in the risk group, and then eventually spread throughout the whole population.

I guess I would define intelligence as having a brain with neural connections. That is an interesting topic that I won't touch.

Maybe HIV was a bad example.

I stopped taking the coconut oil when I started the Beta Glucan.

[struggle83]

Removing the viral DNA from the human DNA in infected neurons would be monumental and probably an unnecessary overcomplicated task. The best thing to do would be to kill all HSV containing cells, preferably by stimulating your immune system into doing that. Our immune system is better equipped for the job, gene and cell therapy proves this. It has all the necessary tools to get it done and will always do it better. It just has to be persuaded.

The problem with a mass slaughter of infected neural cells is that this could be devastating on the nervous system. You might end up with severe nerve damage. There's no telling. I guess that where murine models come in handy. Poor mice.

I'm not against the idea, however. I think it's an option.

[Herpes Awareness]

I have to disagree with that last statement. This virus doesn't have a "plan" with respect to the host. It doesn't have intelligence or even a metabolism. Viruses have no evolutionary strategy so they don't care if they kill the host in 20 days or cause irreparable damage over a whole lifetime. The ones that kill quickly come and go but they can still continue to exist (ie flu viruses like the black plague are still around today). Look at HIV, it used to kill within a few years but it spread like mad. Virus existence is a very complex thing. Scientists are still trying to figure out where viruses came from and what evolutionary role they play. Just my opinion. Not intended to flame. It's an interesting topic.

You haven't really understood it. The 'plan' are the forces of natural selection and mutation. You will find that if a new virus mutation were to wipe out a whole species, that's the end of the virus as well. Not evolutionarily 'successful' for the virus. The purpose of multi-cellular life such as ourselves is to survive and propagate. The 'intent' of a virus is pretty much to do exactly the same, even though it has no intelligence. Your DNA, or the DNA of a worm, has no innate intelligence either, but it appears to have a purpose -- to keep the species going in an environment. This is part of 'the miracle of life' in a way -- not only do lifeforms sustain themselves, but they propagate, use meiotic reproduction to ensure genomic diversity, etc. In the same way, a 'successful' virus adapts itself so that it doesn't kill its host. Consider HHIV -- if it ended up wiping out the species, no more HHIV either -- by definition, the virus was unsuccessful at doing its job -- replicating and transmitting without finally annihilating itself. You might think that a 'doomsday virus' that wiped out every species on the planet was 'successful', but the hallmark of success is for the infective organism to continue its own existence. (The thing is, viruses like HIV often jump from other species, where they may be more lethal. Then they often mutate into a less lethal form -- or wipe out the species, e.g. feline AIDS, Tasmanian devils.)

[struggle83]

You haven't really understood it. The 'plan' are the forces of natural selection and mutation. You will find that if a new virus mutation were to wipe out a whole species, that's the end of the virus as well. Not evolutionarily 'successful' for the virus. The purpose of multi-cellular life such as ourselves is to survive and propagate. The 'intent' of a virus is pretty much to do exactly the same, even though it has no intelligence. Your DNA, or the DNA of a worm, has no innate intelligence either, but it appears to have a purpose -- to keep the species going in an environment. This is part of 'the miracle of life' in a way -- not only do lifeforms sustain themselves, but they propagate, use meiotic reproduction to ensure genomic diversity, etc. In the same way, a 'successful' virus adapts itself so that it doesn't kill its host. Consider HHIV -- if it ended up wiping out the species, no more HHIV either -- by definition, the virus was unsuccessful at doing its job -- replicating and transmitting without finally annihilating itself. You might think that a 'doomsday virus' that wiped out every species on the planet was 'successful', but the hallmark of success is for the infective organism to continue its own existence. (The thing is, viruses like HIV often jump from other species, where they may be more lethal. Then they often mutate into a less lethal form -- or wipe out the species, e.g. feline AIDS, Tasmanian devils.)

No, you haven't understood it. There is no "plan". Start by reading The Blind Watchmaker.

Also read up on error catastrophe. This is when RNA viruses mutate themselves into extinction. Is that part of the "plan"?

Life is not a miracle. The word "miracle" is a human term and the Universe has no understanding of it.

This thread has gone way off subject. I won't be pulled into this theological direction.

[SuperManFace]

I have to disagree, and say that DNA is incredibly intelligent. Reality itself with all its laws, which somehow can swirl amino acids together into a double helix shape after being polarized is somekind of intelligence going on. Everything you do is your DNA expressing itself. If it disappeared there goes your intelligence out the window. Think about it, it interacts and changes with the environment, it mutates, it controls executive functions, and it is creative. That is intelligence right there....in my perception anyway. I can't say I am right or your wrong, or that your perception or belief is wrong, the only thing I can do is disagree.

[struggle83]

I have to disagree, and say that DNA is incredibly intelligent. Reality itself with all its laws, which somehow can swirl amino acids together into a double helix shape after being polarized is somekind of intelligence going on. Everything you do is your DNA expressing itself. If it disappeared there goes your intelligence out the window. Think about it, it interacts and changes with the environment, it mutates, it controls executive functions, and it is creative. That is intelligence right there....in my perception anyway. I can't say I am right or your wrong, or that your perception or belief is wrong, the only thing I can do is disagree.

DNA isn't intelligent by itself. There has to be a process that reads DNA. It's like data on a harddrive. The data isn't intelligent but the chip that processes it has intelligence. It would make for interesting debate over a few beers

The laws of physics are what binds this all together. I recommend What Is Life by Schrodinger.

[camomile]

The most interesting item in this article is:

That is a critical piece of information. If you ask your doc they will tell you HSV doesn't spread around the body. You can now tell them that that is garbage and you now have science to prove it. I've been espousing for months that there is no reason for this virus to settle into your ganglia and just stop there. It has the keys to the castle.

I have never read how HSV spread from one site into different organs/muscle cells etc. It seems these Simplex viruses do cause all kinds of havoc. Only problem is, we only deal with the problem when it/they happen (over a long time).

[struggle83]

I have never read how HSV spread from one site into different organs/muscle cells etc. It seems these Simplex viruses do cause all kinds of havoc. Only problem is, we only deal with the problem when it/they happen (over a long time).

My infection has spread all over my body, from the infection in my nether region to my spine to my brain. I've also experienced problems in my lungs, GI tract, urinary tract and reproductive organs. Not to mention my nervous system and muscles.

The problem is that herpes researchers are either studying it in animal models (umm boring) or in petri dishes (umm lame and useless for most part). There is no modern study of the virus in human populations apart from fucking shedding and OB frequency. They did all those lame EMPIRICAL studies in the 60's. They need to do more post mortum research on deceased with herpes infections.

[camomile]

I've also experienced problems in my lungs, GI tract, urinary tract and reproductive organs. Not to mention my nervous system and muscles. It's run amok in me.

The problem is that herpes researchers are either studying it in animal models (umm boring) or in petri dishes (umm lame and useless for most part). There is no modern study of the virus in human populations apart from fucking shedding and OB frequency.

They did all those lame EMPIRICAL studies in the 60's. They need to do more post mortum research on deceased with herpes infections. Carve those cadavers open and track the little fucker all over. Let's see what this little "skin irritation" is capable of.

Is Valtex helping you with these? (sorry for the lame question..) have you tried Famivir? I mentioned "lame", I often wondered if these drugs could make H worse in ppl who have long-term systemic H. H seems to attack human liver, which these drugs metabolize. This bug also seems to know how to disable/pass through our defense unnoticed.

As for Neurology, their mentality is, diagnose diseases when it happens (and they still get it wrong over a number of yrs and keep changing their mind) and conveniently not addressing the root cause e.g. virus. I am aware that Neuros do know nowadays that H can invade CNS (and the rest I guess..). The reason they don't address this is because there is no drugs for stopping this virus apart from the same old acyclovir. This is really a very retroactive route in 21st Century!! I also cannot believe, clinicians are seriously considering giving Acyclovir to ppl with Alzeheimer's. Once your brain is full of "tangles", is it wise to expect Acyclovir to "do the trick" for example? Sometimes, those researchers make me wonder..

Imho, I feel you/we shouldn't worry too much about ppl who are only mildly affected saying "it's no big deal". I have a funny feeling that it's something to do with our individual genetic aspect, which in turn affects our immune system.

[struggle83]

Is Valtex helping you with these? (sorry for the lame question..) have you tried Famivir? I mentioned "lame", I often wondered if these drugs could make H worse in ppl who have long-term systemic H. H seems to attack human liver, which these drugs metabolize. This bug also seems to know how to disable/pass through our defense unnoticed.

As for Neurology, their mentality is, diagnose diseases when it happens (and they still get it wrong over a number of yrs and keep changing their mind) and conveniently not addressing the root cause e.g. virus. I am aware that Neuros do know nowadays that H can invade CNS (and the rest I guess..). The reason they don't address this is because there is no drugs for stopping this virus apart from the same old acyclovir. This is really a very retroactive route in 21st Century!! I also cannot believe, clinicians are seriously considering giving Acyclovir to ppl with Alzeheimer's. Once your brain is full of "tangles", is it wise to expect Acyclovir to "do the trick" for example? Sometimes, those researchers make me wonder..

Imho, I feel you/we shouldn't worry too much about ppl who are only mildly affected saying "it's no big deal". I have a funny feeling that it's something to do with our individual genetic aspect, which in turn affects our immune system.

I agree with much of that. Valtrex isn't helping me, nor did acyclovir or famvir. I started the acyclovir/valtrex at the start of my infection and it didn't seem to do anything. I have a laundry list of symptoms that would blow the mind of any ID doc. I also accept that it is genetics/immune system.