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Hi: I am new to this site. I got my results yesterday. I am Herpes 2 positive with no outbreaks. Feel confused and looking for support. This news were told to me on the phone with almost none explanation.

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Hi: I am new to this site. I got my results yesterday. I am Herpes 2 positive with no outbreaks. Feel confused and looking for support. This news were told to me on the phone with almost none explanation.

Hey Freeflight, Welcome to our site :hithere: . I hope you know you are never alone again :) we are here to help you learn good informations and to learn to cope. here is a book www.westoverheights.com , please when your feeling better take time to read up on the h. We also have a lovely herpes library here on the front ofthe forum page to the right. Yes, the people who call can be so cold and seem uncaring, its how most got their blood results, I know its how I got my blood. But the DR who swabbed me she was a bitch, she says to me "Go home and wash up" I was married for crist sakes and she treated me like dirty trash. Its okay I now have a whole new community of support ad so do you :) . Just sit back , lets get you educated and take the fear out of herps. Hugs, Ace :wavey:

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Hello everyone, just saying hello and another gay to add to the mix. Im new to this party so don't know a lot yet, but feel free to say hello .

Hey hey Law we met in chat room, but I just thought I would say :hithere: again . Good to see you have made your way around the forums. Don't forget to read this book , its a wonderful book filled with good info about herps. Take care hon, hugs Ace :)

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  • 9 months later...

I am Randi from NC . Very honest about my condition which unfortunately keeps me lonely in the gay community. When I was dating men they don't seem to have much of a problem but finding a woman that is excepting and willing to do the research to be informed is a different story. I found out 9 years ago I contracted it from my husband. I was upset but excepting. Any advice would be appreciated.

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Hi trippy welcome honey. You can message those in these threads , we have many lovely users here who just love to Chat. Some have email address in their profiles that alerts them when someone sends them a message. Try it I know you will make many friends here. I'm married and he's still non h. Just because we have it, I promise that doesn't mean we pass it, there things we can do to limit the transmission rates and reduce shedding. I've been remarried for 23 years and he's still tested negative, I'm also a ghsv2 woman. Take care and I'm here if I can help. Take care, hugs Aces

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    • BabyGirl
      I just stared dating someone who does not have HSV.How long after the sore is healed should I wait before having sex?  I’ve had HSV2 for over 10 years. I rarely have outbreaks going months even years until recently. When I do I get some tingles and one sore in the same spot. But recently, In the last 3 months it’s happened twice. 🤦🏼‍♀️
    • JDMT_176
      If you want to know whats going on when applying it, this was the only study I found describing it. Hard to read through as very technical, but am copy paste parts I found of use. Tables also useful to show which genes are expressed more.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416766/   "A petrolatum donut was applied with a cotton swab to form about a 1 cm diameter donut on skin on the inner aspect of the upper arm. Then a separate cotton swab was dipped in a 2% SADBE solution (w/v) in DMSO, and the swab was then used to apply about 10–20 mg of solution over about a 1 cm diameter circle within the petrolatum donut. Immediately after application, the application site was covered with TEGADERM. Subjects were advised to remove the TEGADERM and rinse and wipe the spot 3 h later.   "Thus in essentially every case, the SADBE treatment changed the group A subjects by day 57 to make them much more like the group B and C subjects who have better immune control of their HSV‐1 infection than the group A subjects were on day 1.   "Others have previously shown that CD8+ T cells are important in controlling herpes labialis outbreaks.23, 24, 25, 26, 27, 28, 29, 30, 31, 32 Our data are consistent with this. The helper/cytotoxic cell ratio (CD4+/CD8+ ratio) was 5.25 in group A versus 3.07 and 3.15, respectively in groups B and C (Table (Table3).3). The P‐value is less than 0.20 for comparisons of group A to both groups B and C, and if groups B and C are pooled and compared to group A the P‐value is 0.065, almost significant. This is consistent with prior evidence discussed below that CD8+ T cells are important and effective in controlling HSV recurrences.   "Consistent with our finding lower anti‐HSV‐1 IgG levels correlate with better control of HSV‐1 outbreaks, Spruance et al. also found lower serum anti‐HSV‐1 antibodies in HSV seropositive patients with a history of frequent herpes labialis than in seropositive persons with no history of herpes labialis.33   "Several prior reports also found IFN‐gamma to be important in controlling HSV infection and reducing HSV outbreaks. Dobbs et al28 showed that CD8+ T cells were able to clear an HSV‐2 infection in transgenic mice, but that efficacy was blocked in vivo by anti‐IFNG IgG. Liu et al31 showed that CD8+ T‐cells could prevent HSV‐1 reactivation from latency in excised trigeminal ganglia (TG), and that IFN‐gamma protein was produced by the CD8+ T cells, and that neutralization of IFN‐γ significantly enhanced the rate of HSV‐1 reactivation from latency in TG cultures. Spruance et al33 found that IFN‐gamma protein levels in PBMC supernatants stimulated with HSV‐1‐infected cell extracts were lower in frequent herpes labialis sufferers than HSV‐1 seropositive controls, consistent with the present result for IFNG gene expression in PBMC stimulated with heat‐killed HSV‐1. McKenna et al7 assayed IFN‐gamma in medium of PBMCs cultured in vitro and stimulated with inactivated HSV‐1 and found IFN‐gamma was at higher concentrations in medium of PBMCs from infrequent herpes labialis sufferers than frequent sufferers, also consistent with our findings. Cunningham et al34 showed higher interferon levels (including alpha, gamma, and lambda) in supernatants of PBMCs stimulated with heat‐killed HSV‐1 virus correlated with longer time to next herpes labialis recurrence. Carr et al35 showed that transgenic expression of IFNG could prevent HSV‐1 reactivation in a mouse model.
    • JDMT_176
      Hi Kurdt- I was thinking back in 2018-2019 there was several threads from viral frog that he was applying a 2% solution very frequently. Like several times a week. From what I gather- it didnt work for him at the time. I think too much applied caused immune chaos or something.  The most recent Square X trial was terminated but this was the dosing frequency that was used in the trial below: I was planning on using Group C protocol. Group A is most frequent. Something to think about.  https://clinicaltrials.gov/ct2/show/results/NCT03521479?term=squarex&draw=1&rank=4   Protocol:  Arm/Group Title Group A Group B Group C Group D  Arm/Group Description Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 2% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 0.5% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0, month 3, and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months).   Adverse Reaction Table: Arm/Group Title Group A Group B Group C Group D  Arm/Group Description: Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 2% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 0.5% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0, month 3, and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Overall Number of Participants Analyzed 10 10 10 10 Measure Type: Number Unit of Measure: events         Localized reaction (rash, erythema, itching/pruritus, warmth/burning) at application site 24 14 17 6 Generalized adverse events (related, possible or greater) 2 3 1 0 Generalized adverse event (unrelated) 4 7 6 4  
    • Cas9
      No, it doesn't look like herpes at all. Why haven't you simply seen a dermatologist?
    • Neveragain99
      I've been having bumps appear on my face around my mouth for a couple years now. They usually take several weeks to disappear but these current lesions have been here for months now and don't seem to be healing at all. I've been applying salicylic acid and oil of oregano twice a week but am having no luck and it appears to be getting worst. This has completely destroyed my self esteem and I've given up on trying to date...  I've attached an image if anyone could help me out with a diagnosis or some type of regiment to help make them go away i'd be forever indebted!  Thanks 
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