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angelstar838

A cure for herpes on the way Agenus?

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angelstar838

In an an} exciting bit of news in the struggle against genital herpes, one of the planet’s foremost research firms just reported that it {could} be closing in on producing a vaccine for the HSV-2 virus responsible for the STD. American medical firm Agenus Inc. introduced findings from its ongoing research last month showing that its new product, HerpV, successfully eliminated the presence of genital herpes symptoms in men and women who took part. Even more impressively, the drug also appeared to prohibit the virus’ capacity to implant itself in another host.

Why Does HerpV Work?

Without delving} too deep} into complex biology, HerpV works by triggering} an immune system response that improves cells’ ability to identify the herpes virus. This is achieved by introducing what is {known as} a “heat shock protein”, or HSP, into the blood. As soon as it’s in the system, the HSP binds itself to the surface of healthy cells, consequently causing infected cells to become incompatible and incapable of attaching themselves (i.e., replicate).

By blocking the genital herpes virus from duplicating, HerpV fundamentally makes it inducing~unable to induce} outbreaks in current patients and non-contagious to uninfected people. This is unquestionably an amazing proposition} for the estimated 16% of the human population currently suffering from genital herpes.

How Notable Are Agenus’ Results?

During the course of what} was referred to as a Phase 1 study, 100% of herpes-infected subjects who were given a HerpV injection exhibited a major increase in antigen-targeted cell immune mechanism response to the virus. In common terminology, this indicates that the T cells in each and every one of the study’s subjects became immune to HSV-2 immediately after being administered HSP.

Dr. David Koelle, a medical professor at the University of Washington School of Medicine, presented the data on behalf of Agenus and made the following statement, “I believe these data represent the first finding of their kind in humans in genital herpes treatments.” The physician went on to say, “The potential use for a therapeutic vaccine candidate such as HerpV is in managing outbreaks and ultimately disease transmission in patients with genital herpes.”

Could This} Mean That A Vaccine Is Coming Soon?

The consequences of these primary results on HerpV are enormous. Dr. Koelle recognized} this point thusly}, “Being able to impact and possibly decrease the spread of genital herpes would be a huge step in stemming this epidemic that affects one in six adults in the U.S.” With all of the excitement that this announcement generated, a logical question was “So, how close is the HerpV vaccine to being released to the public?”

Even though it may not be very far off, it is unlikely that the vaccine will become accessible to existing genital herpes sufferers anytime in the near future. Agenus is right now initiating Phase 2 of its research on the drug’s efficiency and, if it continues to be successful, will then be required to submit to the FDA-approval program before launching the vaccine. Due to the fact this process can often take years, the effort to get rid of herpes symptoms in men and women may not be as near to its conclusion as all of us wish to think.

Does this article hold any credibility?

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Jay9876

"American medical firm Agenus Inc. introduced findings from its ongoing research last month showing that its new product, HerpV, successfully eliminated the presence of genital herpes symptoms in men and women who took part. Even more impressively, the drug also appeared to prohibit the virus’ capacity to implant itself in another host."

You can find the identical article from several sources. Unfortunately, there is no mention of the claims in quotations above from any Agenus press release. I did search for a reliable source for the above article but did not come up with anything creadible.

Agenus did release finding of increased immune response from all 7 or 8 individuals that were giving the full vaccine during the phase I trials. There are NO reports whether these individuals have had outbreaks or documented shedding since administration. I'm sure there is data on this somewhere.

In addition, the result in preclinical trials in Guinea pigs show LESS than significant result on decreased outbreaks. They claim this poor result is due to this vaccine being primarily manufactured for humans and not guinea pigs.

It would be nice to know if the claims in the article came possible from an inside reliable source but I believe we may never know.

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shimshim

HI All

I infected last year on April 2010. I took the valterex for 6 months and I stoped it. As soon as I stop the pills , I start to have out breaks. Then , again I took the pills for 6 months and I stop it again. Unfortunatly , my body did not chnage and I satrt to have an out break again. It is hurting me and I can not go on any relationship this way.

Can any one give me a sulution? What can I do to have less out break? Do I need to take pills for the rest of my life every day?

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helpiamconfused2
"American medical firm Agenus Inc. introduced findings from its ongoing research last month showing that its new product, HerpV, successfully eliminated the presence of genital herpes symptoms in men and women who took part. Even more impressively, the drug also appeared to prohibit the virus’ capacity to implant itself in another host."

You can find the identical article from several sources. Unfortunately, there is no mention of the claims in quotations above from any Agenus press release. I did search for a reliable source for the above article but did not come up with anything creadible.

Agenus did release finding of increased immune response from all 7 or 8 individuals that were giving the full vaccine during the phase I trials. There are NO reports whether these individuals have had outbreaks or documented shedding since administration. I'm sure there is data on this somewhere.

In addition, the result in preclinical trials in Guinea pigs show LESS than significant result on decreased outbreaks. They claim this poor result is due to this vaccine being primarily manufactured for humans and not guinea pigs.

It would be nice to know if the claims in the article came possible from an inside reliable source but I believe we may never know.

I guess it is dangerous to "assume" anything here; however, I don't see where they would go forward if there was no sizeable decrease in outbreaks and shedding. Otherwise, why would moving forward be worth their time and the shareholders/creditors money?

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Jay9876

Your same thoughts have crossed my mind. I would give a kidney to find out the long term results of those that have been fully vaccinated in phase I.

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Monique
Your same thoughts have crossed my mind. I would give a kidney to find out the long term results of those that have been fully vaccinated in phase I.

Hi Jay, just wondering if you wrote to them if they would at the very least 'hint' at the results?

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Movingslowly

In all reality how soon does anyone of you think a therapeutic vaccine or better treatment will be on the market? Like 5 or 6 years?

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helpiamconfused2
Hi Jay, just wondering if you wrote to them if they would at the very least 'hint' at the results?

Monique, if it is a publicly traded company, they cannot "hint" anything or they will be providing you with "insider information" which is strictly forbidden and punished because, acting on this info, you could unjustly benefit from sale/purchase of the stock. Therefore, it is highly unlikely (not impossible) to get "hints." My personal opinion is the bigggest "hint" is whether they move forward in the trials or not.

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Movingslowly

I believe itll b another 5 yrs b4 we hear any real encouraging news about a drug coming to the market.

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wwdamron
In all reality how soon does anyone of you think a therapeutic vaccine or better treatment will be on the market? Like 5 or 6 years?

thats probably a good guesstimate. maybe a liitle sooner. but you are probably in the ballpark.

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yoyoyoyo

yeah, when big monies are involved (and there are none bigger than US pharama) information control is critical. Press releases that spin investors up with hope for potential new products can backfire when those products get derailed in the pipeline. A company appear mismanaged when it cannot deliver on its promises. As a result, new information comes out in bursts, often from indirect sources.

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