Jump to content
World's Largest Herpes Support Group
Sign in to follow this  
angelstar838

A cure for herpes on the way Agenus?

Recommended Posts

angelstar838

In an an} exciting bit of news in the struggle against genital herpes, one of the planet’s foremost research firms just reported that it {could} be closing in on producing a vaccine for the HSV-2 virus responsible for the STD. American medical firm Agenus Inc. introduced findings from its ongoing research last month showing that its new product, HerpV, successfully eliminated the presence of genital herpes symptoms in men and women who took part. Even more impressively, the drug also appeared to prohibit the virus’ capacity to implant itself in another host.

Why Does HerpV Work?

Without delving} too deep} into complex biology, HerpV works by triggering} an immune system response that improves cells’ ability to identify the herpes virus. This is achieved by introducing what is {known as} a “heat shock protein”, or HSP, into the blood. As soon as it’s in the system, the HSP binds itself to the surface of healthy cells, consequently causing infected cells to become incompatible and incapable of attaching themselves (i.e., replicate).

By blocking the genital herpes virus from duplicating, HerpV fundamentally makes it inducing~unable to induce} outbreaks in current patients and non-contagious to uninfected people. This is unquestionably an amazing proposition} for the estimated 16% of the human population currently suffering from genital herpes.

How Notable Are Agenus’ Results?

During the course of what} was referred to as a Phase 1 study, 100% of herpes-infected subjects who were given a HerpV injection exhibited a major increase in antigen-targeted cell immune mechanism response to the virus. In common terminology, this indicates that the T cells in each and every one of the study’s subjects became immune to HSV-2 immediately after being administered HSP.

Dr. David Koelle, a medical professor at the University of Washington School of Medicine, presented the data on behalf of Agenus and made the following statement, “I believe these data represent the first finding of their kind in humans in genital herpes treatments.” The physician went on to say, “The potential use for a therapeutic vaccine candidate such as HerpV is in managing outbreaks and ultimately disease transmission in patients with genital herpes.”

Could This} Mean That A Vaccine Is Coming Soon?

The consequences of these primary results on HerpV are enormous. Dr. Koelle recognized} this point thusly}, “Being able to impact and possibly decrease the spread of genital herpes would be a huge step in stemming this epidemic that affects one in six adults in the U.S.” With all of the excitement that this announcement generated, a logical question was “So, how close is the HerpV vaccine to being released to the public?”

Even though it may not be very far off, it is unlikely that the vaccine will become accessible to existing genital herpes sufferers anytime in the near future. Agenus is right now initiating Phase 2 of its research on the drug’s efficiency and, if it continues to be successful, will then be required to submit to the FDA-approval program before launching the vaccine. Due to the fact this process can often take years, the effort to get rid of herpes symptoms in men and women may not be as near to its conclusion as all of us wish to think.

Does this article hold any credibility?

Share this post


Link to post
Share on other sites
Jay9876

"American medical firm Agenus Inc. introduced findings from its ongoing research last month showing that its new product, HerpV, successfully eliminated the presence of genital herpes symptoms in men and women who took part. Even more impressively, the drug also appeared to prohibit the virus’ capacity to implant itself in another host."

You can find the identical article from several sources. Unfortunately, there is no mention of the claims in quotations above from any Agenus press release. I did search for a reliable source for the above article but did not come up with anything creadible.

Agenus did release finding of increased immune response from all 7 or 8 individuals that were giving the full vaccine during the phase I trials. There are NO reports whether these individuals have had outbreaks or documented shedding since administration. I'm sure there is data on this somewhere.

In addition, the result in preclinical trials in Guinea pigs show LESS than significant result on decreased outbreaks. They claim this poor result is due to this vaccine being primarily manufactured for humans and not guinea pigs.

It would be nice to know if the claims in the article came possible from an inside reliable source but I believe we may never know.

Share this post


Link to post
Share on other sites
shimshim

HI All

I infected last year on April 2010. I took the valterex for 6 months and I stoped it. As soon as I stop the pills , I start to have out breaks. Then , again I took the pills for 6 months and I stop it again. Unfortunatly , my body did not chnage and I satrt to have an out break again. It is hurting me and I can not go on any relationship this way.

Can any one give me a sulution? What can I do to have less out break? Do I need to take pills for the rest of my life every day?

Share this post


Link to post
Share on other sites
helpiamconfused2
"American medical firm Agenus Inc. introduced findings from its ongoing research last month showing that its new product, HerpV, successfully eliminated the presence of genital herpes symptoms in men and women who took part. Even more impressively, the drug also appeared to prohibit the virus’ capacity to implant itself in another host."

You can find the identical article from several sources. Unfortunately, there is no mention of the claims in quotations above from any Agenus press release. I did search for a reliable source for the above article but did not come up with anything creadible.

Agenus did release finding of increased immune response from all 7 or 8 individuals that were giving the full vaccine during the phase I trials. There are NO reports whether these individuals have had outbreaks or documented shedding since administration. I'm sure there is data on this somewhere.

In addition, the result in preclinical trials in Guinea pigs show LESS than significant result on decreased outbreaks. They claim this poor result is due to this vaccine being primarily manufactured for humans and not guinea pigs.

It would be nice to know if the claims in the article came possible from an inside reliable source but I believe we may never know.

I guess it is dangerous to "assume" anything here; however, I don't see where they would go forward if there was no sizeable decrease in outbreaks and shedding. Otherwise, why would moving forward be worth their time and the shareholders/creditors money?

Share this post


Link to post
Share on other sites
Jay9876

Your same thoughts have crossed my mind. I would give a kidney to find out the long term results of those that have been fully vaccinated in phase I.

Share this post


Link to post
Share on other sites
Monique
Your same thoughts have crossed my mind. I would give a kidney to find out the long term results of those that have been fully vaccinated in phase I.

Hi Jay, just wondering if you wrote to them if they would at the very least 'hint' at the results?

Share this post


Link to post
Share on other sites
Movingslowly

In all reality how soon does anyone of you think a therapeutic vaccine or better treatment will be on the market? Like 5 or 6 years?

Share this post


Link to post
Share on other sites
helpiamconfused2
Hi Jay, just wondering if you wrote to them if they would at the very least 'hint' at the results?

Monique, if it is a publicly traded company, they cannot "hint" anything or they will be providing you with "insider information" which is strictly forbidden and punished because, acting on this info, you could unjustly benefit from sale/purchase of the stock. Therefore, it is highly unlikely (not impossible) to get "hints." My personal opinion is the bigggest "hint" is whether they move forward in the trials or not.

Share this post


Link to post
Share on other sites
Movingslowly

I believe itll b another 5 yrs b4 we hear any real encouraging news about a drug coming to the market.

Share this post


Link to post
Share on other sites
wwdamron
In all reality how soon does anyone of you think a therapeutic vaccine or better treatment will be on the market? Like 5 or 6 years?

thats probably a good guesstimate. maybe a liitle sooner. but you are probably in the ballpark.

Share this post


Link to post
Share on other sites
yoyoyoyo

yeah, when big monies are involved (and there are none bigger than US pharama) information control is critical. Press releases that spin investors up with hope for potential new products can backfire when those products get derailed in the pipeline. A company appear mismanaged when it cannot deliver on its promises. As a result, new information comes out in bursts, often from indirect sources.

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
Sign in to follow this  

Advertisement

Try a Lysine supplement for cold sores

  • The Hive is Thriving!

    • Total Topics
      67,972
    • Total Posts
      453,236
  • Posts

    • Godcanhealme
      @cas9 actually I think it’s you who doesn’t understand proof, proof by nature is subjective, so what is proof to me might not be proof to you... I have seen many cases where people have nothing to gain sharing their stories about herpes, and healing themselves, now if you continually search for this you’ll find it in comment threads or perhaps blogs.... perhaps they are lying? Well...Maybe some, but to think everyone who has claimed to heal themselves of herpes is a liar is simply a belief...  if you wanna believe that, go ahead, but after careful  analysis of many stories and researching the virus myself I am convinced the body can rid itself of herpes, what comes in, can come out, it just takes time and effort... But I like to keep it simple, God can heal anything so at this point you guys are just speaking nonsense  
    • Wanteducated
      So my 20 year old daughter and I just found out she has genital herpes.  She is away at college and dealing with it on her own.  I am trying to be as supportive as I can by reading everything I can find from reputable sites.  She is staying busy this week with as she is involved with her schools freshman orientation for the new class coming in.  She was told by an urgent care doctor that she had it Visually, they did a blood test and called her to confirm it is herpes.  I told her to ask what type and she was told they don’t really type anymore because there is to much gray area but that it is a new infection. From what I have read that seems odd and she should find out what type.  I told her to inform anyone she may have had sex with in the last 6 months, she said she told the guy and he was an ass about it which of course makes the emotional side worse.  She is emotionally a wreck about it and I am trying to help her understand it’s not the end of the world.  Of course being 20 she feels she will not have the chance to meet anyone who would want to date her now. Any advice would be great....she is still in the middle of her first outbreak but I think the antiviral has been helping since she went to the doc as soon as she thought something wasn’t right.  I just want to help her as best I can!
    • BuggedOut
      Sorry for the long post. Just giving some backstory..... Hello. I'm new to this site. I was told I had HSV2 about 5 years ago. I had no clue because I never had any symptoms. I was just getting some blood work done while pregnant after switching to a new ob/gyn and this was discovered. Pregnancy was ended for personal reasons. Still afterwards never had any outbreaks or symptoms or anything. Fast forward to June I started feeling irritated down there. I was dealing with a lot of stress at this time. I ended up taking a pic of what it looked like down there so I could see what was going on. I only saw 1 spot. In the pic you will see the spot on top. It always just looked like a crater or something. It never blistered up or popped or crusted up. I knew I had the virus so I started researching outbreaks and pics and things. I wasnt sure if this was an out break or not because most of what I was dealing with didnt match up. I never felt sick. It didn't hurt to sit or wear panties. I didnt have any tingling or itching or burning sensation. I just felt irritated. I know every case is different though. So then I researched some home remedies and I ended up buying lysine 1000 mg to take and also used tea tree oil and acv diluted w/ water. Once I started messing with it, it started burning when urine got on the spot. And I think I didn't dilute the acv enough. I took 2 lysine pills a day until I wasnt feeling anything down there. So after a few days this healed up and everything was fine again but the spot never really went away. Things have been settled down and no stress since then. All of a sudden yesterday morning I started feeling that same irritation again. This morning I felt around down there and felt nothing so I took a pic again and the thing on bottom is what I found. I put some acv and  tea tree oil on it again.  And same as last time...ever since I touched it, it's been hurting just a tad and it looks exactly the same. I'm not sure if this is a outbreak or not but I'm pretty sure it is. I'm just not experiencing most of the symptoms I read about. Can someone give me their opinion please? Thank you.
    • PeaceNeeded
      Hello I am very interested about your case because seems similar to my condition. https://honeycomb.click/topic/76355-are-these-my-secondary-outbreaks-or-what-pics Please let us know what doctors will tell.
    • Wanteducated
      So my 20 year old daughter and I just found out she has genital herpes.  She is away at college and dealing with it on her own.  I am trying to be as supportive as I can by reading everything I can find from reputable sites.  She is staying busy this week with as she is involved with her schools freshman orientation for the new class coming in.  She was told by an urgent care doctor that she had it Visually, they did a blood test and called her to confirm it is herpes.  I told her to ask what type and she was told they don’t really type anymore because there is to much gray area but that it is a new infection. From what I have read that seems odd and she should find out what type.  I told her to inform anyone she may have had sex with in the last 6 months, she said she told the guy and he was an ass about it which of course makes the emotional side worse.  She is emotionally a wreck about it and I am trying to help her understand it’s not the end of the world.  Of course being 20 she feels she will not have the chance to meet anyone who would want to date her now. Any advice would be great....she is still in the middle of her first outbreak but I think the antiviral has been helping since she went to the doc as soon as she thought something wasn’t right.  I just want to help her as best I can!
×

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.