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lookingforhope

so who do you think is the closest...

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lookingforhope

I know It's a matter of opinion..but who do we think is the closest to an actual cure? (By cure, I mean ridding the body of the virus completely). And who do we think is closest to making it so that somebody who is already infected cannot transmit to somebody else? Just curious to see what everybody thinks.

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Jay9876

Good question lookingforhope,

Closest to complete cure:

- Bloom with hammerhead ribozyme technology

- Cullen with mRNA silencing technology

- Celletics with meganuclease technology

I'm not sure who is closer between Cullen and Bloom. All I have heard is that Cullen is at least 5 years away from clinical trials. As for the french company Celletics they seem very secretive so I have no idea where they are at. I do know that Celletics has patented their HSV meganuclease for both HSV-1 and HSV-2 but they are currently involved in a patent dispute with this technology.

Closest to stopping possibility of transmission:

This is a hard one to answer. There are several companies starting clinical trials with vaccine designed to boost the immune system (i.e. Agenus, Coridon, Genocea, Sanofi Pasteur). Whether any of these vaccines that stop transmission 100% is it difficult to say. Most of these immune enhancing vaccine are aimed at reducing outbreaks and shedding and so far no one has claimed that their vaccine will totally prevent outbreaks and shedding (this cannot be answered prior to conducting clinical trials).

There is an antiviral made by Aicuris called AIC316 that will be going into phase 3 trials next year. They will be experimenting with dosage to see how close they can get to eliminating outbreaks and shedding. Also Chimerix has a drug CMX001 that may work better than AIC316 but the only herpes virus they are currently concentrating on is CMV and have not started clinical trials on HSV patients. It is also worth to keep an eye on Nanoviricides as they are promoting an interesting technology and no one knows if Bavituximab will effectively work for HSV.

The above is just my opinion. I am interested to see what others say.

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lookingforhope

Thank you...I have been trying to educate myself and of course getting my hopes up. I guess I just want to see who to keep an eye on.

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Hottfoxxy

I honestly don't believe any of these people will come close to anything it hurts me to say that but it's the truth there are so Many people infected they make more money off treating that curing so do the math!!! Thus world is greedy and all they care about is money.. People have suffered over 30 yrs or more with this shit crap of a disease so If they havnt seen a cure what makes u think there will be one in the future... Don't mean to be negative but it's the truth it's all bullshit.. So tired of feeling like a leapar and an outcast.. I feel that I don't even deserve to havev intimate contact with anyone.. I feel uncomfortable about talking about sex around others because I'm ashAmed and feel dirty.. This virus sucks ass and u hate it

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Teacher Man

@Lookingforhope...It is exciting that so many researchers and companies are working on vaccines/treatments/cures for herpes. Yes, trials and approval take a long time, but eventually something new is bound to happen. If nothing else, a new type of treatment or antiviral may happen. It will likely be a few years, but given the power of the internet and the advances made by Cullen, Bloom, Halford, and others, the future looks bright for our cause.

@Hottfoxy - Time to find some perspective. We all know that feeling of shame and pain about having this little virus. However, I implore you not to think of yourself as an outcast or leper. Part of being a human being means having to deal with the pain that life brings. Yes, getting this virus kind of sucks. But it doesn't change one thing about the essece of who you are. You are still worthy of love, intimacy, connection, sex, and peace of mind. No one can lead you there, or lead any of us there for that matter. But remember that you're not alone. Sometimes when fall into the trap of negative thinking and brooding, I watch the following clip. Hope it helps you. ONE LOVE.

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lookingforhope

I'd be happy with more effective antivirals for now...I'm interested in non transmission above all, because if you can't give it to anybody, then you don't have to tell anybody lol.

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beautifulmorning

wwdamron was amazing at updating the forums on HSV-1/HSV-2 suppression/treatment/cure development. He has been absent for 3 weeks. Hopefully he is just on holiday and will return soon.

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JHenry

In a private exchange he and I had several weeks ago, I believe he did mention traveling away for a bit. I just can't remember the details at this moment. JHenry.

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Movingslowly

In complete agreement with Jay9876. Dr. Cullen is another 15 years away my educated guess. Dr. Bloom will have his treatment available before Dr. Cullen because Bloom is further along. The future for a cure or vaccine for preventative or therapeutic treatment is a good 10 years away because of that tedious FDA process. I honestly believe Aicuris will have AIC316 on the market before any other company. I can settle for this until a cure or permanent suppression of some sort is available. We can't give up though. Signing petitions, sending emails, and donating is our only chance for bringing a treatment to market sooner.

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chen24689

I personally believe Dr.Bloom's therapy is 6-7 years away, including the FDA process, if he has the adequate fund. And it will be around 2 years for us to know whether it will work or not. (The rest 5 years or so will all be clinical trials and approval procedures.)

In complete agreement with Jay9876. Dr. Cullen is another 15 years away my educated guess. Dr. Bloom will have his treatment available before Dr. Cullen because Bloom is further along. The future for a cure or vaccine for preventative or therapeutic treatment is a good 10 years away because of that tedious FDA process. I honestly believe Aicuris will have AIC316 on the market before any other company. I can settle for this until a cure or permanent suppression of some sort is available. We can't give up though. Signing petitions, sending emails, and donating is our only chance for bringing a treatment to market sooner.

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