Sign in to follow this  
Followers 0
ICherri

Herpes and Alzheimer's

11 posts in this topic

:(

Today I discussed an article about the connectin between HSV-1 (cold sores only) and Alzheimer's. Some of the articles were confusing and but they seem to state that HSV-1 particles are found in Alzheimer patients and are a big link to the plaques that develop in the mind. I added a link:

http://www.huffingtonpost.com/dr-david-perlmutter-md/alzheimers-herpes-could-be-a-cause_b_814047.html

This is scary but I still know I am confused about alot of the facts and hoping someone can shed light on the issue.

I know HSV-1 is not the main cause but I think they are saying it can heighten the chances of someone already predisposed to Alzheimer and people with recurrent outbreaks are at higher risk than those who just have the virus without OB's. Or is this all just a theory?

Share this post


Link to post
Share on other sites

What I have read is this, although it might not be totally accurate. In autopsies performed on Alzheimer's patients, something like 90% had HSV present in their brain tissues as well. Which came first and triggered the other, I don't know.

Share this post


Link to post
Share on other sites

hi hows it going,they still don't know the affect that the herpes has on the brain and the alzheimers brains all had a certain gene that has been known about for years.So if you dont have the gene -no alzheimers in family history your maybe safe.The fact that 90% of the brains had herpes could simply mean that 90% of people have herpes damage to their brains in some form or another.

Here is a link to a 60 minite program,A television documentry that shows people who had their memory wiped by herpes.

http://sixtyminutes.ninemsn.com.au/article.aspx?id=8222628

I know this doesnt really help and is a little freaky but some reasurance is that enceph is extremly rare and the flue kills more than herpes.

Heres another two links about the latest research on the alzeimers and herpes

http://www.sciencedaily.com/releases/2008/12/081207134109.htm

http://www.sciencedaily.com/releases/2011/10/111017102557.htm

Share this post


Link to post
Share on other sites

I wouldn't wish that on anyone, but if those memory wipes start happening more often, I bet they would do more research in HSV.

Share this post


Link to post
Share on other sites
:(

Today I discussed an article about the connectin between HSV-1 (cold sores only) and Alzheimer's. Some of the articles were confusing and but they seem to state that HSV-1 particles are found in Alzheimer patients and are a big link to the plaques that develop in the mind. I added a link:

http://www.huffingtonpost.com/dr-david-perlmutter-md/alzheimers-herpes-could-be-a-cause_b_814047.html

This is scary but I still know I am confused about alot of the facts and hoping someone can shed light on the issue.

I know HSV-1 is not the main cause but I think they are saying it can heighten the chances of someone already predisposed to Alzheimer and people with recurrent outbreaks are at higher risk than those who just have the virus without OB's. Or is this all just a theory?

Interesting study,

This study suggests, that using anti-viral medication and/or *hsv vaccines(which are only in the test phase) as a possible prevention of Alzheimer's, am i reading this correctly?

Share this post


Link to post
Share on other sites

Yes and the more people that know that herpes affects the brain whether or not the true cause of alzheimers the better as the fact that 90% of peoples brains are affected at some point in time means the implications are huge.However this has its down side as meds like draco which cause cell death may kill neurons in the brain???

This research has been going since at least 2008 so you would think someone would have tried valtrex by now even if self medication.

Also how many peoples brains are autopsied anyway to say whether its in 90% of adult brains as Dr Itzhaki implies.To say adult brains is a bit mysteriouse to me as hsv 1 isnt that wide spread untill at least 60 years old unless its caused by chicken pox??

Does the fact that alzheimers has a special gene mean only they have brain outbreaks and does this account for the fact that some people are aysmtomatic??

I was chatting to someone latley who was diagnosed with hvs 2 hvs1 and his mother informed him that he had cold sores as a child which he didnt recall.Lots of people have bad recollection of their childhood you might say but also lots of people were infected at a young age as well and did it affect their recollection??These are questions that i come up with all the the time as i have a seriouse memory disfunction that ive had all my life and probably will never get an answer.So maybe I was just old before my time.lol

Share this post


Link to post
Share on other sites

Hey,

Thanks for adding to my post. I do get ur anger at the down play of HSV-1..trust me!!!

But there is advances being made..here a link:

http://www.slu.edu/rel-news-herpes-vaccine-14

I also wonder about chicken pox and cold sores lol.

The thing is I can't make myself go insane wit worry or anger.

This is my only life and it is what it is..I try to not spread it by dating only positive people and not sharing glasses or even kissing my nephews and nieces but what else can I do..I deserve to be happy too and so do u.

Share this post


Link to post
Share on other sites

From what I have read it's a case of chicken and egg.

Some figures suggest that 90% of people carry the HSV virus so the chances of it being discovered in alzheimers patients will be high, it makes logical sense.

Whether it is a factor in alzheimers developing needs more research.

Share this post


Link to post
Share on other sites

Yes the fact that its in 90% of people and is discoverd in a select group of people does make sense,I think that the fact that it was discoverd in their brains is isnt that logical and acceptable.

I presume that a dinasour laid an egg and out came a chicken so theres that question answerd.LOL

Share this post


Link to post
Share on other sites
Yes the fact that its in 90% of people and is discoverd in a select group of people does make sense,I think that the fact that it was discoverd in their brains is isnt that logical and acceptable.

I presume that a dinasour laid an egg and out came a chicken so theres that question answerd.LOL

Thank you always wanted to know the answer lol.

HSV lives in the nerves so it makes sense to me that it would be found in the brain. The important question is that we need more research - having worked with people with alzheimers it is a horrible and I hope that I never suffer from it.

Share this post


Link to post
Share on other sites
Hey,

Thanks for adding to my post. I do get ur anger at the down play of HSV-1..trust me!!!

But there is advances being made..here a link:

http://www.slu.edu/rel-news-herpes-vaccine-14

Oh my gosh, they need to continue that study right now! What the heck are they waiting for???????

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
Sign in to follow this  
Followers 0

  • Newbies

  • Latest Buzz

    • Unrequited
      Fair enough. I took from reading Halfords essay was that, it did decrease, but there was no indication it was in any way permanent and your immune system could easily come back up to levels of defense it previously had. It's late and I cannot be bothered to read the studies. You have convinced me. I was quite worried actually about the possible ability for antivirals to reduce the ability of the immune system to fight the virus as I was going to the doctors tomorrow to get a prescription. Not because I need to, but to reduce transmission for someone I care about. I was worried that it might be a bad idea and had certain thoughts of just not pursuing a relationship with her. This has helped my resolve, to the doctors it is.
    • Unrequited
      I AM SO ANGRY! SO SO ANGRY. No, i'm not angry at herpes. I am not angry at my giver (stupid thing to say)............. No i'm not '@#%ing ANGRY AT THAT FFFS!! No, I am angry that for years I have felt bad for having herpes, like there was something wrong with me, that I was dirty or tainted. That i wasn't lovable, that I had to keep a secret...... A secret, a secret that half of the world have?  Do I not tell people I am male, or have brown hair, do I hide this?  Hiding it, and being ashamed, it is just delusional. It's insanity, a worldwide joke...... It's just, it's just, imbecilic! That's what it is.. Herpes is just a virus, a stupidly amazingly ultra common virus, that's been around for hundreds of millions of years............. -  Repeat after me, FOUR BILLION PEOPLE HAVE EITHER HSV1 OR HSV2. Parents purposefully go out of their way to make sure their kids get Chickenpox.... I am angry at this cultural bullshit stigma, placed upon herpes, an insidious cultural hypnosis ! I am just dumbfounded, utterly dumbfounded. Every bastard has it, EVERYONE! Or if they don't, their best friend or mum or sister or son or wife or boss or the old lady who sells you flowers. The most wonderful, amazing people you have ever met, the kindest, bravest selfless souls have herpes. IT IS A FACT OF LIFE, JUST LIKE BREATHING... But people are SHAMED into thinking it's a horrible thing. This is just insanity.. But we destroy ourselves emotionally because of a LIE. YOU HAVE BEEN LIED TO. HAVE NO DOUBT ABOUT IT. The stigma and the shame is a lie, forced on you through unspoken cultural naratives and fears. I am angry..... I am angry for all the people who are destroyed by the stigma, my heart goes out to them, those that shut themselves away, feel unloved, feel like their life is over. People have taken their lives over the stimga, it is so upsetting to think about. You are lovely, and you are wonderful and you are truly amazing. Please don't believe the bullshit I love you, i don't care if you have herpes or not. You are wonderful. I'm off to bed. Night x
    • VVK
      So we seem to have some inferences being made based on data from two studies that were both done in 1988. The following may be a bit TLDR for those who don't have a scientific background (see TLDR summary at the end), but for those that do here goes: One study (Erlich's) shows daily acyclovir dosing decreased antibody concentrations on average by 10% (as measured by optical density, a difference between ~0.165 to ~0.15), although 22% of those trial participants getting a daily dose of acyclovir actually had an increase in antibody concentrations. In discussion of those results: "Although some reports have suggested that the first HSV recurrence following cessation of long-term acyclovir chemosuppression may be more severe than those previously experienced, we did not observe this in our study." The other study (Gold's) involves 33 people, of which 22 got daily oral acyclovir and 11 got a placebo. Already, the treatment group is double the size of the placebo group. The assignment of the groups is also odd. Interestingly, 16 of the 22 assigned to daily oral acyclovir got outbreaks anyway while on acyclovir. Some of those assigned to the daily acyclovir came into the study already having more outbreaks than those that went into the placebo group. Some of those participants on placebo ended up having fewer outbreaks than those that were on acyclovir. For Gold's data, I recommend looking at Figure 2 and 3 rather than Figure 1.. Figure 1 shows the changes in the antibody levels of two individuals (for comparison), whereas Figure 2 and 3 shows the entire pool of participants. Figure 2  and 3 doesn't show which participant's antibody levels went up or down, but generally you can see it's not a very dramatic change and that there are large variations in the changes. Here's the kicker for you from the same article (Gold's): Correlating antibody decreases and clinical parameters of disease. To determine whether the magnitude of decrease in antibody levels during one year of acyclovir treatment had an effect on the course of disease during and after therapy, we evaluated the relation between clinical parameters and the peak height for each antibody and for "total" antibody (total of peak heights for gB, gG, gCgE, VP16, and gD) for each acyclovir-treated patient. The clinical parameters were as follows: (1) time to first recurrence after therapy, (2) duration of the first recurrence after therapy, (5) duration of pain of first recurrence after therapy, and (4) number of breakthrough recurrences during therapy. No correlation was detected between the magnitude of decrease in any antibody or "total" antibody and any of these clinical parameters (data not shown). There are other gems in the discussion as well - for example, lower gB levels were associated with shorter outbreak pain duration. Those with lower levels of the other antibodies also had fewer lesions in subsequent outbreaks. Interesting read. As much as Dr. Halford likes to use Figure 1 of Gold's article, the rest of it doesn't quite fit his message. Once the legs of the table are taken out, the rest of Dr. Halford's argument about HSV antiviral drugs topples down. TLDR summary: Even if antibody counts can be shown to convincingly be decreased as a result of daily antiviral dosing over a prolonged period of time, that is an effect on antibody counts. This doesn't translate to an effect on the immune system's ability to fight HSV - probably because HSV usually tricks the immune system into recognizing useless portions of the virus that don't help with actually controlling outbreaks.
  • Cure Research

  • Trending