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Dummy

Interesting and recent article.. Just trying to keep folks in the loop!

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Dummy

According to a new study published in the Advance Online Publication of Nature, Yale researchers are presently busy developing a new vaccine that could potentially keep people from becoming infected with HSV (herpes simplex virus, i.e. genital herpes).

The main drive behind their endeavor is represented by the fact that, although cases of genital herpes translate into noteworthy health problems and even death on quite a regular basis, proper treatment and effective means of immunization are still lacking.

Thanks to funding provided by the US National Institutes of Health, this team of specialists was able to perform laboratory experiments on mice.

The official website for the Yale University informs us that it was these experiments which lead them to the conclusion that activated T cells (i.e. antibodies for the immune system) could be recruited directly into the vaginal tissue by means of chemokines (i.e. compounds which act towards mobilizing the immune cells).

Apparently, once they are set in place, these T cells provide protection against HSV and keep it from spreading as it normally would.

Up until now, T cells have not been harnessed in organs such as intestines, central nervous system, lung airways and the vagina, seeing how they all restricted their access.

Akiko Iwasaki, presently employed as a professor of immunobiology at Yale School of Medicine, made a case of how, “This new vaccine approach can work with any vaccines that elicit strong T cell immunity, and will set the stage for protection against infectious diseases by setting up memory T-cells at the site of exposure.”

The researchers speculate that this vaccination model could also be efficient went it comes to providing some levels of protection against other sexually transmitted infections such as HIV-1.

As Akiko Iwasaki puts it, “This technology can be potentially applied to other infectious agents that enter through a given portal, such as the genital tract, respiratory tract, the skin, or gut.”

http://news.softpedia.com/news/Yale-Scientists-Plan-Anti-Genital-Herpes-Vaccine-300431.shtml

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lovelyoptimistic

someone posted a smililae article a few days ago. This one does a better job of explaining the mode of action. I wonder if this is something that can be combined with t cell vaccines like genocea and herpv, to help harness the t cells in the vaginal areas, and prevent transmission and outbreaks.

edit: maybe it is the exact same article lol. Maybe I just didn't read it carefully last time

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thomboy

forgive me for asking, but taking advantage of the above comment.

the coridon struck a deal to use technology in their vaccine vector, increasing your project.

* My question is the same as lovelyoptimistic, will genocea or agenus would find a lot of bureaucracy to utilize this technology in their products (through bureaucracy fda) as their vaccines are already focused on cell "T", the ultilização this technology would only target their product (which already proved safe for use in case of agenus), for a specific area?

will already could test this new idea in the current tests?

I apologize if this was a stupid question, but no possibility can be ruled out until the end of this fight.

Hugs to all and a great afternoon

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thomboy
forgive me for asking, but taking advantage of the above comment.

the coridon struck a deal to use technology in their vaccine vector, increasing your project.

* My question is the same as lovelyoptimistic, will genocea or agenus would find a lot of bureaucracy to utilize this technology in their products (through bureaucracy fda) as their vaccines are already focused on cell "T", the ultilização this technology would only target their product (which already proved safe for use in case of agenus), for a specific area?

will already could test this new idea in the current tests?

I apologize if this was a stupid question, but no possibility can be ruled out until the end of this fight.

Hugs to all and a great afternoon

someone would be interesting to ask these questions directly to agenus, genocea or yale, just to know if this would be a viable possibility?

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