Jump to content
World's Largest Herpes Support Group
Sign in to follow this  
2ifbysea

IgG negative, IgM positive?

Recommended Posts

2ifbysea

Need some advice on test results...

My husband had a one night stand. 15 weeks post exposure I sent him to his doc for STD testing including HSV IgG. My husband has never had any symptoms of oral or genital herpes. His test results came back as....

HSV IGG type 1 positive at 2.0

HSV IGG type 2 negative at <0.2

For some reason the test also included an HSV IGM which was read as...

HSV IGM type 1 weak positive

type 2 positive

This is exactly what the test said. I am a nurse pracitioner and thought I had a fair understanding of HSV. I did not think IgM could differentiate between type 1 and 2. Since he had no symptoms, I'm not sure why this was drawn but now I don't know what to do with the results. This was done about 2 weeks ago and my husband still has not had any symptoms. The doc wanted him to start anti-virals (he thinks it is a false positive but wanted him to do this to prevent passing it to me since my herpes tests were negative) and have him retest in 6 weeks. I told my husband not to start the anti-virals yet because I don't want to muddy the waters further when the test is redrawn.

Does this sound like a false positive? Should he start the antivirals or not? Would love to hear thoughts from anyone. Thanks!

Share this post


Link to post
Share on other sites
RealisticGal
Need some advice on test results...

My husband had a one night stand. 15 weeks post exposure I sent him to his doc for STD testing including HSV IgG. My husband has never had any symptoms of oral or genital herpes. His test results came back as....

HSV IGG type 1 positive at 2.0

HSV IGG type 2 negative at <0.2

For some reason the test also included an HSV IGM which was read as...

HSV IGM type 1 weak positive

type 2 positive

This is exactly what the test said. I am a nurse pracitioner and thought I had a fair understanding of HSV. I did not think IgM could differentiate between type 1 and 2. Since he had no symptoms, I'm not sure why this was drawn but now I don't know what to do with the results. This was done about 2 weeks ago and my husband still has not had any symptoms. The doc wanted him to start anti-virals (he thinks it is a false positive but wanted him to do this to prevent passing it to me since my herpes tests were negative) and have him retest in 6 weeks. I told my husband not to start the anti-virals yet because I don't want to muddy the waters further when the test is redrawn.

Does this sound like a false positive? Should he start the antivirals or not? Would love to hear thoughts from anyone. Thanks!

Here's what all the experts in the field of STIs/HSV would tell you:

Ignore the IgM results.

They tell us that they are unreliable and non-specific, and that the IgM-based testing is prone to cross-reactions with other viruses.

Incidentally, with a numeric value of 2.0, it is possible your husband's test results are a "false positive." This applies to the Herpeselect ELISA test kit, because the published index values for that kit have been shown to be skewed. Any value below 3.5 is suspect.

It is more likely to be a false positive since he is without any symptoms.

:wavey:

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
Sign in to follow this  

  • The Hive is Thriving!

    • Total Topics
      69,116
    • Total Posts
      463,532
  • Posts

    • VladimirM
      I do belive. It is going to be SADBE and Sqarex. I am on it and it is great.
    • Miss Annie
      Thank you. Yes, I was on Positive Singles and met someone I was with for 2 years. We recently broke up but may work things out. Truth be told, dating is touch. With or without a virus. 
    • Godsaveus
      A possible problem is that it will possibly be overshadowed by emails regarding other health problems such as cancer which carry no stigma and therefore have a more massive amount of requests.
    • WilsoInAus
      @nydb1 I feel you can be quite confident that you do not have genital herpes here.  Please return to your doctor for further diagnosis and treatment.
    • f*ckedOver
      Maybe this has been asked already, but is there way we could get everyone on the site to write emails to the Bill and Melinda Gates foundation?  If they got 1000s of emails about this issue maybe they would fund people like the researchers at Penn?????????
×

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.