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StayingUpbeat

Good technical paper about HSV vaccines, why they've failed and what's on the horizon

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StayingUpbeat

I realize its not exactly cure research but its recent and an interesting read if you're curious why and how the previous and potential vaccines work.

"Towards a Rational Design of an Asymptomatic Clinical Herpes Vaccine: The Old, the New, and the Unknown"

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324142/

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garban

Hi StayingUpbeat,

Thanks for this article. The paper goes to depth about the current research. Epitopes based vaccines may be the future. Lets hope for the best on that.

From what I see the next few vaccines we are looking at are:

Genocea

Agneus

Vical

Coridon/Allied Health Care

Those are all for HSV-2 though. No idea when there will be something for us HSV-1 folks.

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Voyager2

I have genital HSV-2, but I imagine cold sores and genital herpes are equally stressful, just in different ways, so it is interesting that the four companies all targeted HSV-2. It could be because it's the traditional virus that causes the more stigmatized genital herpes and they had to pick one. We should probably ask them.

I think that when any HSV-2 vaccine first shows evidence of really and truly working, the savy business people in charge will set up a separate clinical trial using HSV-1 people. But HSV-1 people should just get the HSV-2 vaccine anyway, as it will already have been proven safe in a phase 1 trial.

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