Dr. Rider, DRACO and Q&A's

[Broken_14]

Thank you for signing up to receive updates on DRACOs research. We do appreciate your support and will look to provide you with ongoing important updates.

As you already know, DRACOs research and development may lead to a cure for virtually all viruses. More importantly, DRACOs may end suffering and save millions of lives!

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[tom343]

This thing got funding from DARPA, not enough funding for this seems like a story that is a long way off. Also the whole concept seems to say beware of side effects. Also I'd recogn this could take 2 decades to actually get to mass production.

[Gothic Beauty]

This thing got funding from DARPA, not enough funding for this seems like a story that is a long way off. Also the whole concept seems to say beware of side effects. Also I'd recogn this could take 2 decades to actually get to mass production.

Where did you read anything about side effects? They were on small animal trials (mice) last time I saw an update so now they just have to do large animal trials and then they can start phase 1 of actual clinical trials. There were no reports about any side effects in the mice. The main problem seems to be having a place to do the research (i.e. a lab). I would think with where they are at it would only be 1 decade not 2.

[tom343]

I think in the article below it states it will be a long time before human trials for Draco can occur and because your own cells and virus cells become similar, Draco could lead to some serious side effects as it could takeout your own cells. It could be why DARPA pulled the funding.

http://www.bbc.com/news/magazine-16165605

[sonofagun]

1. It's at the same point since ppl were discussing this in 2012. Obviously the failure to get anywhere would add further doubts about this so called 'novel' concept. You don't have any info either so what are you saying?
   

If I don't have any legitimate information, I don't say anything. I certainly don't make sh!+ up! I never made any erroneous, unsubstantiated claims against the potential drug product called Draco, you did. I merely questioned your lack of evidence to back your claims. I accused you of being provocative, misinformed, assuming, and lazy. I also accused you of misinterpreting the one referenced article you provided. I always take the time to understand any article I provide as a reference to my point before I interpret it whereas apparently for you, time is too precious to spare your readership misinterpretations. Personally, as I make a statements on this forum, I attempt to support those claims with direct, relevant quotes from scientific observation out of respect for those who choose to read my replies. I do not engage in supposition or conjecture because it is inefficient and not compelling . If I were to engage in abject opinion making then I would forewarn my readership that I was doing so with preambles to my opinions which take the form of something like: I think..., I believe.., In my opinion.., Now, I'm just spit balling here... Etc. I certainly wouldn't attempt to annex my opinions to the subject or the supporting object in a vain attempt to legitimize those opinions, as I felt that you had when you claimed that Draco was no longer funded by DARPA because DARPA believed the drug was "screwed". You could have of claimed something like, "I have no evidence to back this up, just some baseless assumptions, but I think Draco is screwed because I have read nothing in three years time that suggests that Dr. Rider has moved forward with his antiviral drug." At least those who read your replies would appreciate that you're at least taking credit for your unsubstantiated statements.

"Obviously the failure to get anywhere would add further doubts about this so called 'novel' concept."

Why did you place quotes around the word 'novel' as if to suggest that Draco is anything other than an original concept. And I don't believe it's a forgone conclusion that Draco has failed to progress because you simply haven't read about it in some time. I've read plenty from you recently and you have proven that merely being well published is certainly no substitute for progress. This sentence is an example of how unsubstantiated are your conclusions and how boring. This is also an example of how unfit your ideas are to this particular forum. Ideas expressed here should be substantial and progressive, not just provocative. Perhaps your perfunctory, critical nature would best expressed under a more appropriate context and moniker. Perhaps you should start a forum entitled "This will never be a cure" or simply "No reason, not a cure." or "abandon hope, all ye who enter here."

[tom343]

Perhaps you should start a forum entitled "This will never be a cure" or simply "No reason, not a cure." or "abandon hope, all ye who enter here."

I think there are plenty of good scientists working for us and we'll have a cure way before Draco ever comes into even a phase 1. That's if it ever makes it into a phase 1 at all. Like I said if this thing works the way it does then Draco should have been the first drug taken for Ebola. Instead they've been wasting time obviously with vaccine trials in guinea. If you believe in this so much why don't you get in contact with the scientist and take it yourself? See if it clears the hsv and do us all a favour.

[sonofagun]

I think there are plenty of good scientists working for us and we'll have a cure way before Draco ever comes into even a phase 1. That's if it ever makes it into a phase 1 at all. Like I said if this thing works the way it does then Draco should have been the first drug taken for Ebola. Instead they've been wasting time obviously with vaccine trials in guinea. If you believe in this so much why don't you get in contact with the scientist and take it yourself? See if it clears the hsv and do us all a favour.

"Like I said if this thing works the way it does then Draco should have been the first drug taken for Ebola."

Your deductive argument is irrational. There are many Ebola drugs that could have been used to treat Dr. Kent Brantly, many that have tested well. However according to the article to which I have provided a link, selecting ZMAPP amongst a group of possible drug candidates to treat Dr. Brantly was a result of luck for the drug had yet to undergo human trails before it was selected.

http://www.dw.com/en/secret-serum-liberia-ebola-drug-used-on-brantly-is-only-one-of-many-in-development/a-17654230

"Instead they've been wasting time obviously with vaccine trials in guinea."

There is federal protocol to follow when testing drugs which is hardly considered a waste of time and it is quite mandatory. Delays in drug testing could happen for a multitude of reasons as each step forward in drug development is usually a step up in cost. Often, small drug companies need to take necessary time to procure adequate funding before progressing to the next level. Again, that is never considered a waste of time. Most importantly, when a doctor uses his considerable intellect and talent, to attempt to ease the suffering of millions of people by curing viral diseases, that should certainly never be considered a waste of time.

[Gothic Beauty]

If I don't have any legitimate information, I don't say anything. I certainly don't make sh!+ up! I never made any erroneous, unsubstantiated claims against the potential drug product called Draco, you did. I merely questioned your lack of evidence to back your claims. I accused you of being provocative, misinformed, assuming, and lazy. I also accused you of misinterpreting the one referenced article you provided. I always take the time to understand any article I provide as a reference to my point before I interpret it whereas apparently for you, time is too precious to spare your readership misinterpretations. Personally, as I make a statements on this forum, I attempt to support those claims with direct, relevant quotes from scientific observation out of respect for those who choose to read my replies. I do not engage in supposition or conjecture because it is inefficient and not compelling . If I were to engage in abject opinion making then I would forewarn my readership that I was doing so with preambles to my opinions which take the form of something like: I think..., I believe.., In my opinion.., Now, I'm just spit balling here... Etc. I certainly wouldn't attempt to annex my opinions to the subject or the supporting object in a vain attempt to legitimize those opinions, as I felt that you had when you claimed that Draco was no longer funded by DARPA because DARPA believed the drug was "screwed". You could have of claimed something like, "I have no evidence to back this up, just some baseless assumptions, but I think Draco is screwed because I have read nothing in three years time that suggests that Dr. Rider has moved forward with his antiviral drug." At least those who read your replies would appreciate that you're at least taking credit for your unsubstantiated statements.

"Obviously the failure to get anywhere would add further doubts about this so called 'novel' concept."

Why did you place quotes around the word 'novel' as if to suggest that Draco is anything other than an original concept. And I don't believe it's a forgone conclusion that Draco has failed to progress because you simply haven't read about it in some time. I've read plenty from you recently and you have proven that merely being well published is certainly no substitute for progress. This sentence is an example of how unsubstantiated are your conclusions and how boring. This is also an example of how unfit your ideas are to this particular forum. Ideas expressed here should be substantial and progressive, not just provocative. Perhaps your perfunctory, critical nature would best expressed under a more appropriate context and moniker. Perhaps you should start a forum entitled "This will never be a cure" or simply "No reason, not a cure." or "abandon hope, all ye who enter here."

Ya! You tell his irritatingly informed butt!

[Broken_14]

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[tom343]

 

Ya! You tell his irritatingly informed butt!

lol whilst I think everyone would agree Draco would be amazing, the questions I stated about it were genuine and they were not answered. It's interesting to note what bill halford said about Draco. 

 

Achesvee, you asked…..”Hi Bill, what are your thoughts on DRACO?”

I wish you could see me rolling my eyes in the back of my head as I am asked this question about the Molecular Tooth Fairy for the 20th time.

DRACO is like Santa Claus. Sounds great to kids, but as you grow up and learn about how the world really works, you realize it’s a pretty silly premise.

Likewise, DRACO makes the most sense to people who know absolutely nothing about biology, pharmacology, and have no knowledge that DRACO violates all the major rules for a viable drug (e.g., cost per treatment; solubility; off-target effects; feasibility of delivery to internal organs; route of administration). DRACO = treating / preventing disease with nucleic acids. To the best of my knowledge, there is not a single viable drug based on a nucleic-acid based therapy that a person ingests. Gene therapy with even the best of viral vectors is an uphill battle. The proposal that someone could pop a nucleic acid pill in their mouth and be cured of influenza or whatever ails you is preposterous.

If you are talking about direct i.v. injection of massive amounts of a small nucleic acid into the bloodstream (instead of pills), now I am getting nervous about this too as it sounds like a recipe for acute liver toxicity and death.

So my thoughts on DRACO…….what a lame idea. It gives me pause to think how many man-hours have been lost discussing this abject waste of space of a concept.

Hope that clarifies my position.

– Bill H.