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Broken_14

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So far, we've only raised a little over 10,000$ from the campaign and obviously we know that we need more than that in order for Dr. Rider to progress DRACO and test in HSV. We've also came to realize that the time frame of DRACO seems like a long time away and without proof some people will not donate. However, if we are able to raise the money Dr. Rider needs it could speed up both the "proof" part and the time frame. If we aren't successful at raising the money than DRACO could disappear for good. Please donate whatever you can, even if it's 5$ and spread the word about the campaign. You can share it those who know your status or email it to your local news department without them having to know your situation or personal information. Visit the campaign at: http://igg.me/at/EndTheVirus

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From Dr. Halford,

"Achesvee, you asked…..”Hi Bill, what are your thoughts on DRACO?”

I wish you could see me rolling my eyes in the back of my head as I am asked this question about the Molecular Tooth Fairy for the 20th time.

DRACO is like Santa Claus. Sounds great to kids, but as you grow up and learn about how the world really works, you realize it’s a pretty silly premise.

Likewise, DRACO makes the most sense to people who know absolutely nothing about biology, pharmacology, and have no knowledge that DRACO violates all the major rules for a viable drug (e.g., cost per treatment; solubility; off-target effects; feasibility of delivery to internal organs; route of administration). DRACO = treating / preventing disease with nucleic acids. To the best of my knowledge, there is not a single viable drug based on a nucleic-acid based therapy that a person ingests. Gene therapy with even the best of viral vectors is an uphill battle. The proposal that someone could pop a nucleic acid pill in their mouth and be cured of influenza or whatever ails you is preposterous.

If you are talking about direct i.v. injection of massive amounts of a small nucleic acid into the bloodstream (instead of pills), now I am getting nervous about this too as it sounds like a recipe for acute liver toxicity and death.

So my thoughts on DRACO…….what a lame idea. It gives me pause to think how many man-hours have been lost discussing this abject waste of space of a concept.

Hope that clarifies my position.

– Bill H."

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Of course he's going to have something negative to say, like he does about everything and everyone else's research but his. However, you're titled to your own opinion as I am mine. 

By the way, Bill H has also stated there is no way to CURE any viral infection/disease. With that said, he said Hep C could NOT be cured. Well, if you keep up with the news or happen to know someone who has/had Hep C and finished the treatment, then you would know that there is a CURE for it.

Also, from what I've gathered from talking to Bill H, his vaccine is live and can't cure someone who is already infected. It is a preventive vaccine for those individuals who do NOT have HSV. I could be wrong but that's what he told me in the spring when I asked him about it. But like I've stated, you're more than welcome to your own opinion, just like everyone else. I respect that. If you don't believe in our mission to raise money to have DRACO tested in HSV (which Dr. Rider picked himself) than, that's your choice. However, I just hope that we raise the money and show that it is effective and safe, just as Dr. Rider believes it will be. 

You should ask Bill about other treatments and vaccines developed by other people and see what he says about the research or efforts to prevent or TREAT this virus. 

Thanks for the insperation to push harder on the DRACO campaign =) 

Edited by Broken_14
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From Dr. Halford,

"Achesvee, you asked…..”Hi Bill, what are your thoughts on DRACO?”

I wish you could see me rolling my eyes in the back of my head as I am asked this question about the Molecular Tooth Fairy for the 20th time.

DRACO is like Santa Claus. Sounds great to kids, but as you grow up and learn about how the world really works, you realize it’s a pretty silly premise.

Likewise, DRACO makes the most sense to people who know absolutely nothing about biology, pharmacology, and have no knowledge that DRACO violates all the major rules for a viable drug (e.g., cost per treatment; solubility; off-target effects; feasibility of delivery to internal organs; route of administration). DRACO = treating / preventing disease with nucleic acids. To the best of my knowledge, there is not a single viable drug based on a nucleic-acid based therapy that a person ingests. Gene therapy with even the best of viral vectors is an uphill battle. The proposal that someone could pop a nucleic acid pill in their mouth and be cured of influenza or whatever ails you is preposterous.

If you are talking about direct i.v. injection of massive amounts of a small nucleic acid into the bloodstream (instead of pills), now I am getting nervous about this too as it sounds like a recipe for acute liver toxicity and death.

So my thoughts on DRACO…….what a lame idea. It gives me pause to think how many man-hours have been lost discussing this abject waste of space of a concept.

Hope that clarifies my position.

– Bill H."

Bill Halford constantly rips everyone else's ideas and trials. Bill Halford says "It gives me pause to think how many man-hours have been lost discussing this abject waste of space of a concept." That's how I feel when I read posts on here about Halford. He needs to be honest with all of the HSV sufferers and let everyone know that his vaccine is for prophylactic purposes. It isn't going to be a miracle vaccine that people on here claim it to be. 

 

 

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Unfortunately, to crap talk another's research if they don't understand is a very common practice.

But yeah, Dr. Ryder has tested it on mice and presented the data.  Dr. Halford, like any pragmatic scientist, could replicate the experiment and do it himself to see if it really works.

 

Edited by Sanguine108
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Not to sound like I am on any level near someone with years of experience in biology and medical research (as I am simply a lay-man), but I wonder on a fundamental level how the process of administering, testing, and observing mice is any different than with human beings.  What I mean by this statement is that (if what Todd Ryder has done is legitimate -- which I am believing is the case), there is a biological, mammaliam organism which has gone through some sort of rigor during DRACO treatment, and essentially stayed alive, and ridden of the aforementioned viruses.  There wasn't any type of weird, magical, and unfeasible process in administering DRACO.  I'm guessing Todd didn't stick a needle through the mouse's a-hole, through the gut, and into the brain, while causing some sort of sequelae... 

In short, why can't such an end result occur with human beings?

Edited by achang28
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Hate to sound like a broken record but Dr. Rider needs to go rogue and perform trials in a different country. His concept is very interesting, so I'm anxious to see/hear results. But with lack of funding, the fickle FDA government organization and up to 15 years clinical trials, it would be logical for him to look into different countries as a Plan B. If he believes Draco will work, then he would. It would be a revolutionary treatment and I personally would travel to the Amazon Jungle, the polar caps of Antarctica, and or Communist North Korea for a cure. In other words, I don't care where treatment is given, I will go there! The FDA's slow, dragging process is harming peoples quality of lives!

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@dont quit! Generally-speaking, I would agree.  But, more importantly, someone would have to manage such a process for Dr. Rider.  Like all companies that are begun today, experienced programmers should focus all their time on building the product.  Dr. Rider should NOT have to worry about all the business, marketing, politics, et. al. stuff...

He's gotta have a partner person or team to own all that other stuff!

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@dont quit! Generally-speaking, I would agree.  But, more importantly, someone would have to manage such a process for Dr. Rider.  Like all companies that are begun today, experienced programmers should focus all their time on building the product.  Dr. Rider should NOT have to worry about all the business, marketing, politics, et. al. stuff...

He's gotta have a partner person or team to own all that other stuff!

I totally agree. If he were to hold trials in another country, he would be able to hire staff needed at a reasonable price versus spending hundreds of millions of dollars in trials in the U.S. He could hire managing personnel, build or rent a lab, hire lab assistants  as well as laborers for a fraction of the price. He could build a nice modern lab in a developing country for 150k. If he waits for 500 million to 1 billion dollars for clinical trials for a product that may not even work, he will probably be waiting for a long time! If I were him, I would consider it because if Draco is proven successful, he would have money coming out of his you know what, as well as the Nobel Peace Prize!! @Broken_14

Edited by dont quit!
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What is ryder's next step? If he has tested it on mice, then isn't the next step humans? Except like the other vaccine creators he'd have to test that even say 500x the Y dose in mice isn't going to affect them in a negative manner. Then what should occur? Someone is just going to have to take a jab or get some serious funding not off crowd funding but off a specific donation firm like the gates foundation or what about the likes of bono? The guy has 2 billion bucks worth of Facebook stock ffs. Make a case and send it off to him. The case should state that herpes is a major gateway disease for HIV, 90% of HIV suffers have genital herpes. Plus Ryder if correct could cure HIV too so you have to make a case and send it off. Also try the Whitehouse reply website, see if Obama will respond. 

Edited by tom343
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I've already wrote Obama and the White House called me, said there was nothing they could do. Everyone on the campaign has reached out to The Gates Foundation and they have not respond. Right now, crowd funding is all Dr. Rider has to get the money he needs to progress DRACO. If we aren't successful, then it could be the end of Dr. Riders research and DRACO. 

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I totally agree. If he were to hold trials in another country, he would be able to hire staff needed at a reasonable price versus spending hundreds of millions of dollars in trials in the U.S. He could hire managing personnel, build or rent a lab, hire lab assistants  as well as laborers for a fraction of the price. He could build a nice modern lab in a developing country for 150k. If he waits for 500 million to 1 billion dollars for clinical trials for a product that may not even work, he will probably be waiting for a long time! If I were him, I would consider it because if Draco is proven successful, he would have money coming out of his you know what, as well as the Nobel Peace Prize!! @Broken_

Dr. Rider is a family man and I don't believe he would be willing to leave the country. We've had several people suggest the same thing and I can run it by the team but I highly doubt it would happen. 

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Dr. Rider is a family man and I don't believe he would be willing to leave the country. We've had several people suggest the same thing and I can run it by the team but I highly doubt it would happen. 

If Dr. Rider wants DRACOs to have any hope of being commercially viable he needs to take every dime of @Broken_14's crowd funding effort, develop a business plan, and solicit venture capital.  At a minimum he should be talking to people like Kevin J. Kinsella or Peter Hébert.  The latter has provided the seed capital to 33 counter-conventional life sciences companies (including Genocea) and the former has been the driving force for dozens of biotech startups.  Given Chip Clark's connection to this site I would imagine he'd be willing to help facilitate the conversation with Hebert.  With the amount of press Dr Rider's gotten the elevator pitch should be cake.

Chip Clark wrote in one of his posts that Genocea is spending 1 million dollars a day on development of GEN-003. That's 1000X the entire goal of the crowd funding campaign.  If Dr. Rider @Broken_14 or anyone else wants DRACO to ever be more than an idea to put on a coffee mug their going to need to write a business plan and start selling some equity. It seems to me that DRACO, Inc. already has several "employees" who are willing to work for free.

Recombinant DNA was an idea in a Pitt lab until Herman Boyer solicited venture capital to found Genentech.  Rational drug design was a mid-level Merck chemist's pipe dream until Josh Boger started Vertex (and developed the first effective AIDS drug).  And ATLAS was a concept in a Harvard virology lab until Chip Clark started Genocea.  The "valley of death" concept is a fallacy perpetuated by scientists who refuse to evolve into the business leader it takes to actually turn a concept into a drug.

If Dr. Rider plan is to sit on his hands and wait for money to fall from the sky DRACO is going to be developed by someone else.  The Chinese are already messing with it and it will simply be a matter of time before someone figures out how to make his combo proteins without violating the IP.  The IndyGoGo campaign is on track to spend $100K buying Petri dishes and killing a half-dozen mice.  That seems like a waste but what do I know.

---

Edited by StayingUpbeat
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We have all wrote different foundations and companies. People want to see DRACO work before they donate large amounts of money. 

People have criticized eveything we have done for this campaing to raise money and gave us more ideas but have yet to help try to spread the word or donate themselves. Right now, if we want to see DRACO progress than its up to us. We will not quit till we raise the money or Dr. Rider receive a large donation or a pharmacy company picks him up. We are working hard for this to become a reality for everyone but there is only so much we can do. We also plan on pushing Dr. Rider along as fast as we can as far as testing it in mice and getting it to clinicl trials. 

Edited by Broken_14
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