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Halford is not working on a cure.... why is there so much excitement ?


herpes-sucks

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His own website states....

"This latter application of a HSV-2 vaccine (i.e., to reduce symptoms in those who already carry the HSV-2 virus) would be more experimental, and less of a sure thing than a preventative HSV-2 vaccine."

He goes on to say.....

"Therefore, once a safe and effective HSV-2 preventative vaccine is identified, it will be relevant to determine if it has potential to also serve as a therapeutic HSV-2 vaccine."

Meaning, he has no current idea if it will be therapeutic to current sufferers. It will have to be determined.... Great for people who may not wish to acquire Herpes, but if 2/3 of the world has it - as stated by the WHO, how about treating the billions that have it !!

Again, I can't figure out why there is so much excitement surrounding Halford. He hasn't even entered PI trials, yet many talk about him, like he's the savior. 

Edited by herpes-sucks
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@lexyz22

Not sure why you are following my posts and making this personal while looking to attack me.  

What are you wanting or hoping to accomplish ?

I am copying a statement from Halford's own website.  Where am I wrong ?

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Here's a different interpretation for you.

Dr. Halford realizes that a preventative vaccine is most important, since it stops the viruses from infecting and establishing new hosts, which would otherwise serve to keep spreading the virus further. If you protect the uninfected population, the virus can't proceed to infect anyone new anymore. Dr. Halford acknowledges that the vaccine might not help those that already have the virus, since that's not the primary purpose of the vaccine. However, it could very well be that the vaccine might still prove to be therapeutic anyway so treating those who are infected with the vaccine would be an avenue to explore.

Think about it this way: if your new partner is vaccinated and can't acquire herpes from you and if you're taking medication to keep your symptoms in check (or, like the majority of those affected, don't have any symptoms anyway..), what's the problem? Do you need anything more?

Dr. Halford's work is important, as is the work of others that are targeting HSV. What's the purpose of this thread?

 

 

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2 hours ago, VVK said:

Here's a different interpretation for you.

Dr. Halford realizes that a preventative vaccine is most important, since it stops the viruses from infecting and establishing new hosts, which would otherwise serve to keep spreading the virus further. If you protect the uninfected population, the virus can't proceed to infect anyone new anymore. Dr. Halford acknowledges that the vaccine might not help those that already have the virus, since that's not the primary purpose of the vaccine. However, it could very well be that the vaccine might still prove to be therapeutic anyway so treating those who are infected with the vaccine would be an avenue to explore.

Think about it this way: if your new partner is vaccinated and can't acquire herpes from you and if you're taking medication to keep your symptoms in check (or, like the majority of those affected, don't have any symptoms anyway..), what's the problem? Do you need anything more?

Dr. Halford's work is important, as is the work of others that are targeting HSV. What's the purpose of this thread?

 

 

Dr. Halford's work is important, as is the work of others that are targeting HSV. What's the purpose of this thread?

-------------------------------

I didn't know that on an open message board that posters had to justify their thoughts or statements... so I wonder, do you ask others what their point it ? If you are a moderator, let me ask you, what is wrong with my post that you feel compelled to jump in and question me ? 

But as you ask, I think it's pretty obvious that there seem to be a tremendous amount of people that blindly tout Halford as the savior, and seemingly believe that he is developing a cure.  I am pointing out that Halford is developing a potential preventative vaccine that has yet to enter P1 trials, and that on his own website he states this.

So again tell me, what is wrong with this where you feel compelled to intervene or interject ? 

Are you looking to shut down free speech by just wanting everyone to conform or have the same thoughts ?

Maybe you'd like if we can just have a thread on how Halford is the greatest human being on the planet and with 100% certainty his vaccine (that hasn't entered P1 trials) will save us all.

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I don't think you're appreciating the due diligence and hesitancy scientists take to not say something is or isn't something until their is data that supports it.  He wouldn't be putting his life's work into this vaccine if he didn't believe it had a reasonable shot. 

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1 hour ago, herpes-sucks said:

Dr. Halford's work is important, as is the work of others that are targeting HSV. What's the purpose of this thread?

-------------------------------

I didn't know that on an open message board that posters had to justify their thoughts or statements... so I wonder, do you ask others what their point it ? If you are a moderator, let me ask you, what is wrong with my post that you feel compelled to jump in and question me ? 

But as you ask, I think it's pretty obvious that there seem to be a tremendous amount of people that blindly tout Halford as the savior, and seemingly believe that he is developing a cure.  I am pointing out that Halford is developing a potential preventative vaccine that has yet to enter P1 trials, and that on his own website he states this.

So again tell me, what is wrong with this where you feel compelled to intervene or interject ? 

Are you looking to shut down free speech by just wanting everyone to conform or have the same thoughts ?

Maybe you'd like if we can just have a thread on how Halford is the greatest human being on the planet and with 100% certainty his vaccine (that hasn't entered P1 trials) will save us all.

Let me ask you this then.. would you have an issue with me or any other user of these forums starting up a thread just for the purpose of saying "herpes-sucks doesn't know what he's talking about"? It would be a thread that would just serve to spread negative messages about you. Posters will quote (or even misquote) you and will discredit you in this thread. There won't be any sources attached when referencing the points that discredit you. Nobody will moderate it for the sake of free speech.

You seem to think that you're running some kind of crusade of awareness here but it's very crude. Sure, you have free speech and you're welcome to it, but I'd question you regardless of whether I was a moderator.

20 hours ago, herpes-sucks said:

He goes on to say.....

"Therefore, once a safe and effective HSV-2 preventative vaccine is identified, it will be relevant to determine if it has potential to also serve as a therapeutic HSV-2 vaccine."

Meaning, he has no current idea if it will be therapeutic to current sufferers. It will have to be determined....

Really? That's genius. Is there any untested vaccine or treatment that is a sure thing before it is even tested? Oops xD trick question. Maybe you can suggest to Dr. Halford a way to design a live vaccine that will make it therapeutic first instead of preventative.

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50 minutes ago, VVK said:

Let me ask you this then.. would you have an issue with me or any other user of these forums starting up a thread just for the purpose of saying "herpes-sucks doesn't know what he's talking about"? It would be a thread that would just serve to spread negative messages about you. Posters will quote (or even misquote) you and will discredit you in this thread. There won't be any sources attached when referencing the points that discredit you. Nobody will moderate it for the sake of free speech.

You seem to think that you're running some kind of crusade of awareness here but it's very crude. Sure, you have free speech and you're welcome to it, but I'd question you regardless of whether I was a moderator.

Really? That's genius. Is there any untested vaccine or treatment that is a sure thing before it is even tested? Oops xD trick question. Maybe you can suggest to Dr. Halford a way to design a live vaccine that will make it therapeutic first instead of preventative.

As a moderator you seem quite biased here. Why/how are you justified asking about making a herpes-sucks thread ? How is this justified to turn this into an attack on me ? Is that what your job or function is ?  I mean your attack proves my point of the irrational blind faith and loyalty shown to a person that hasn't even entered P1 trials is beyond strange. Almost cult like. Too bad the large pharma and biotech companies don't seem to share the same silly enthusiasm that you guys do.

I think you might not be aware that I am hoping for a cure too.  I just don't like being mislead or over hyped with BS.

I have an idea.... Why don't you add up all the 100s and 100s of naive posts that claim with certainty that Halford's (still in development) vaccine is the blockbuster that the world has been waiting for, and has the treatment (which is at this point is unproven), and then compare to the few I have been recently posting, with copying his statements from his own website. I'm sure the people hyping false hope have out posted me 100 to 1. 

 

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@VVK

Really? That's genius. Is there any untested vaccine or treatment that is a sure thing before it is even tested? Oops  trick question. Maybe you can suggest to Dr. Halford a way to design a live vaccine that will make it therapeutic first instead of preventative.

 

Again, your bias, sarcasm and personal attacks towards me seem quite inappropriate for a "moderator"

You seem to be revealing almost an agenda like quality with your continued taunts. 

Is this your function here... to shut down dissent ?

I also noticed that some posts were deleted.  Why ? 

Edited by herpes-sucks
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27 minutes ago, HopefulOne2013 said:

Halford will be no different

 

Impressed with your ability to see into the future.

One major difference with Halford's vaccine... it is replication competent, and this sets it apart from HSV-529.

 

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4 minutes ago, zzzqzzz said:

Impressed with your ability to see into the future.

One major difference with Halford's vaccine... it is replication competent, and this sets it apart from HSV-529.

 

You might want to read this. The HSV-529 vaccine didn't do so well in the preclinical trial. Genocea's did better. Halford's vaccine won't be any different.

http://www.eurekalert.org/pub_releases/2004-12/hms-soe121404.php

Edited by HopefulOne2013
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@VVK

As a moderator ... did you find it appropriate that one member posted about 200 times across every thread - a video of a guy named Sam, telling us his secrets to be happy ?  I mean we got it the first few times. 

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10 minutes ago, zzzqzzz said:

lol I did read it, it said nothing about Halford's vaccine candidates.

True. But it shoots the whole theory of a live vaccine being the best option as a therapeutic vaccine right out the window. 

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If there's an issue with moderation, please start a separate topic indicating said issues so that they can be dealt with. As far as I can tell there are no deleted posts in this thread. If you have issues with someone's posting habbits or signature, report their content and it will be reviewed. As for my alleged personal attacks, herpes-sucks, they might be a figment of your imagination. Regardless, your main argument against Dr. Halford's research is flawed, but you can't seem to admit it. It has been blown out of the water. There's no two ways about it.

 

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1 hour ago, HopefulOne2013 said:

I'm not taking sides here, but here are the preclinical results for HSV-529. They didn't get that great of results when reducing recurrent disease. Halford will be no different. Genocea's results are better.

http://www.eurekalert.org/pub_releases/2004-12/hms-soe121404.php

 

Where's the actual preclinical results? That's a summary that's talking about the success of the vaccine - a substantially stronger T cell response. It also says it has slightly better reduction of recurring disease when compared to subunit vaccines. Do we have any idea of how long the guinea pigs were monitored for the therapeutic effect? Perhaps it takes time to show up? It's also a story from 2004?

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That was taken from the paper. Perhaps someone else has access to the full preclinical trial. There was a more robust response in T cells but they were comparing it to the failed GSK failed trial. It protects from HSV but the results aren't exactly great on the therapeutic front. I want all of the researchers to succeed. I just haven't seen enough evidence that proves that a live vaccine will be better for therapeutic purposes. 

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It could very well be that neither live nor subunit vaccines will have the desired therapeutic effect for every single person. The answer as to why could actually have nothing to do with the vaccines at all and may be more individualized.

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I think everyone is sick of waiting. Some ppl are like 70+ years old now and have been waiting for 50 years. Alot of people never made it. They suffered with herpes since they acquired it. Some ppl killed themselves. Some ppl suffer daily from nerve pain, liver infections, lung infections etc all because of f%cking herpes. I mean come on even the WHO has put the word out - we don't give a toss who makes the vaccine, just make it and give it to us. Everyone is sick of the bs. Billions are infected with one type or the other, everyday more are infected and more suffer. Surely it's time to end it. It is 2015. This must be the last batch of people to suffer from this scum infection. Halford hurry up for protection of future victims as a minimum and everyone else hurry up for all us suffering right now. I want the day when herpes will be wiped out all together. So no one has to go thru the pain and suffering that I and so many countless others have had to endure. 

Edited by tom343
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21 hours ago, VVK said:

If there's an issue with moderation, please start a separate topic indicating said issues so that they can be dealt with. As far as I can tell there are no deleted posts in this thread. If you have issues with someone's posting habbits or signature, report their content and it will be reviewed. As for my alleged personal attacks, herpes-sucks, they might be a figment of your imagination. Regardless, your main argument against Dr. Halford's research is flawed, but you can't seem to admit it. It has been blown out of the water. There's no two ways about it.

 

@VVK As a moderator, I think your job should be to manage gross violations of website policy and participate in discussions with whatever knowledge or incite you propose to offer.... not launch personal attacks on a participating member by following them across various board to confront them.  That almost boarders on cyber-bullying.  Your actions give rise and acceptance to other members like @lexyz22 trashing me.  That is not appropriate or acceptable.

I mean even you state that you " haven't had any interest in my posts".  Does your job duties include antagonizing members ?  Do all posts have to interest you and pass your test to remain here ? 

I wish you would stop this BS, offer an apology, and state that you do not approve of this type of personal attacks and hostile speech... that you deliver.

Really, am I the enemy here simply because I copied text from Halford's own website that stated he was not developing the vaccine as a treatment and it would be more "experimental, and less of a sure thing" ?

If you people want to proclaim that Halford is the Messiah and savior of the Herpes world, go ahead.  I don't care what you believe.  But shouldn't you offer people so desperate for hope, a true sense of reality... and let them hear another side.  Isn't that what a message board is supposed to do.... which is offer discussion.

Again, realize that I don't gain anything if Halford fails.  I want a cure and treatment also.  I just don't understand the blind faith and unwavering support for this guy, or Ella Dawson.... like they have done so much for us and are our only hope.  The reality is so different.

So how is your (and so many others) one sided biased statements with such conviction and certainty - that this Halford guy who is a 20 year researcher that no major pharma or biotech who wants to partner with him, and who hasn't even entered P1 trials....  any different from my opposite perspective, which simply copied his website statement saying he is not working to develop a cure ? 

Edited by herpes-sucks
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21 hours ago, VVK said:

If there's an issue with moderation, please start a separate topic indicating said issues so that they can be dealt with. As far as I can tell there are no deleted posts in this thread. If you have issues with someone's posting habbits or signature, report their content and it will be reviewed. As for my alleged personal attacks, herpes-sucks, they might be a figment of your imagination. Regardless, your main argument against Dr. Halford's research is flawed, but you can't seem to admit it. It has been blown out of the water. There's no two ways about it.

 

@VVK

How is my main statement of copying from Halford's website in his own words, flawed ?????

It clearly states........ "This latter application of a HSV-2 vaccine (i.e., to reduce symptoms in those who already carry the HSV-2 virus) would be more experimental, and less of a sure thing than a preventative HSV-2 vaccine."

Your attacks on me personally are blowing this out of the water.  I wish you'd stop.

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6 minutes ago, herpes-sucks said:

@VVK

How is my main statement of copying from Halford's website in his own words, flawed ?????

It clearly states........ "This latter application of a HSV-2 vaccine (i.e., to reduce symptoms in those who already carry the HSV-2 virus) would be more experimental, and less of a sure thing than a preventative HSV-2 vaccine."

Your attacks on me personally are blowing this out of the water.  I wish you'd stop.

So now me AND VVK are "attacking/trashing" you? Please..

So just to clarify here, EVERY vaccine is experimental and not a sure thing. Genocea didnt have a clue they were going to get 58% reduction, just like Vical didnt expect a 15% reduction. You're doubting a guy who has spent a big portion of his life trying to pursue a legitimate prophylactic vaccine for mankind, rather than big pharma just throwing money at crappy vaccines, he is trying to do something different. A modified version of the virus into a host subject would surely allow the immune response and innate immune surveillance mechanisms to deal with the virus more efficiently, thats my logic, its not scientific but it seems logical. Im sure if you asked Bill himself he could explain the detailed science to you.

 

 

 

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6 minutes ago, lexyz22 said:

So now me AND VVK are "attacking/trashing" you? Please..

So just to clarify here, EVERY vaccine is experimental and not a sure thing. Genocea didnt have a clue they were going to get 58% reduction, just like Vical didnt expect a 15% reduction. You're doubting a guy who has spent a big portion of his life trying to pursue a legitimate prophylactic vaccine for mankind, rather than big pharma just throwing money at crappy vaccines, he is trying to do something different. A modified version of the virus into a host subject would surely allow the immune response and innate immune surveillance mechanisms to deal with the virus more efficiently, thats my logic, its not scientific but it seems logical. Im sure if you asked Bill himself he could explain the detailed science to you.

 

 

 

I pointed out that I want a cure.  The Hep C people just got a cure.  I wish Genocea produced better results also, and I messaged with Chip.  I am not entitled to anything, but I am tired of false hope.  I don't like BS.  Hope is not a strategy. However, if Halford produces a cure, I will personally line up to get it.  I don't care who develops one.  I'll support them.  Halford is however, very, very, very far away... as he hasn't even entered P1 and his vaccine is based on prevention. i just don't get the blind faith and allegiance to this guy.  My money is however on the pharma's or biotechs, as this will be a multi-billion revenue generator for someone, and as they need to appease their shareholders, they will look to make money where they can.  If Halford has the goods, a pharma or biotech will partner with him, or buy him out.  If he can't raise money over the years to get to P1, he has not ability to bring this to market on his own.

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3 hours ago, lexyz22 said:

Your name really says it all. "herpes-sucks". Pessimistic and somewhat depressing.

I don't know if you are referring to the condition of having herpes, or me personally.... as being pessimistic and somewhat depressing.  I thought we were going to lay off the personal attacks.  That serves no purpose.

Have you ever played the lotto ?  If so, all the optimism and hope in the world, hasn't made you a winner. It just gave you false hope for the moment, and the eventual let down when you checked your numbers and had to cancel all the house purchase and exotic travel plans, not to mention not being able to quit your job and telling your boss off.

All I have been doing is copying Halford's own words from his website and showing there may be a different view point to all the blind faith followers that are convinced that he is developing a cure.

For the umpteenth time.... I want a cure also.  I just don't think Halford is the one to deliver, and his timeline is who knows when.  Even his own words on his website back that up.

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