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Larry Corey suggests Re-Activation Controlled at the Skin, Not Ganglion.


lexyz22

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This would make sense why I notice an increased irritation, redness and slight swelling immediately at the spot of infection immediately with caffeine, masturbation/erections/sex, hot water, or friction from running around at work and it against my briefs.  I believe my immune response is strong enough to suppress an OB but not without symptoms  

Notice he mentioned H is very active....contrary to what many claim 

i think H (either type) can and is in a lot of people very active.  Throw in a person who is susceptible to autoimmunity and these T cells might work overtime even after the virus goes dormant thus constant neuralgia, pain, itching, neuropathy even when the virus slows down or goes dormant 

Tenacious thing. Why can't it be lazy like its cousins VZ or EBV.....

 

 

Edited by Guy12
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This is an old article but upon re-reading it, I thought of Ian Frazer and his vaccine. His vaccine seems to stimulate an enormous T Cell response. The only thing I'm concerned about Frazier's vaccine is that I think he needs a bigger antibody response, which may not be produced by his vaccine. Maybe his vaccine in combination with another live vaccine like Halfords or HSV-529 would be sufficient for a near functional cure.

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On 2015-11-29, 8:41:49, dont quit! said:

This is an old article but upon re-reading it, I thought of Ian Frazer and his vaccine. His vaccine seems to stimulate an enormous T Cell response. The only thing I'm concerned about Frazier's vaccine is that I think he needs a bigger antibody response, which may not be produced by his vaccine. Maybe his vaccine in combination with another live vaccine like Halfords or HSV-529 would be sufficient for a near functional cure.

What makes you concerned that the T cell response may not be sufficient?

 

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4 hours ago, Evaluate said:

What makes you concerned that the T cell response may not be sufficient?

Just a hunch but many researchers have stated the need for a well balanced attack against HSV that includes both antibodies and T cells. Being that most sub units have integrated the glycoprotein D as a stimulant for antibodies, I'm not sure that is enough for a strong well balanced response the body needs to halt symptoms and shedding. Hopefully I'm proven wrong in a few weeks when Admedus releases their results.

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On 2015-11-29, 1:09:39, lexyz22 said:

I think it's a mistaken interpretation of the data.. just because there are t cells sitting near the skin surface (old news btw), controlling reactivation there, doesn't mean that herpes activates near the skin and not at the ganglia. In fact, I don't see anything in that article that suggests herpes reactivates at the skin. It makes sense for the body to have t cells defending the skin surface, because herpes leads to skin damage (i.e. sores) and secondary infections that are obviously harmful to the body. However, did they show that herpes actually re-activated in skin cells? I'm not seeing it.

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18 hours ago, VVK said:

I think it's a mistaken interpretation of the data.. just because there are t cells sitting near the skin surface (old news btw), controlling reactivation there, doesn't mean that herpes activates near the skin and not at the ganglia. In fact, I don't see anything in that article that suggests herpes reactivates at the skin. It makes sense for the body to have t cells defending the skin surface, because herpes leads to skin damage (i.e. sores) and secondary infections that are obviously harmful to the body. However, did they show that herpes actually re-activated in skin cells? I'm not seeing it.

Ahh sorry man, feel free to delete this topic. I dont want this to get indexed by people researching etc. 

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There is actually a lot of research surrounding this topic. Larry Corey is one of the top researchers in the field. Most of the therapeutic vaccines are trying to solve this very same puzzle. I would keep the thread open. Just my opinion. 

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6 hours ago, VVK said:

I'm not sure what puzzle you're referring to, HopefulOne2013.

The puzzle of solving the HSV issue at the skin level with a therapeutic vaccine. We all know that a vaccine will not remove the virus from the ganglia. 

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