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Current vaccines in development - Confused ?? Please help !!


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Hello.  New to the board but have been reading the posts as an HSV2 sufferer. 

Can someone with medical knowledge of science, immunology, biology (rather than hype/speculation) please tell me in your opinion what the best (and worst) of the current vaccines in trial or development are for treatment ?  I know from what I have read here there is a lot of discussion on:  Genocea, Admedus, Halford, CRISPR, HSV-529, Albert Einstein Medical. 

Also, what are the pros and cons of a live vaccine for treatment, as it seems like HSV-529 and Halford is focusing on this method.  If someone has HSV2, how would injecting a live vaccine serve as a treatment ?  I understand it may be intended to stimulate the immune system, but if one already has HSV2, doesn't the body already have anti-bodies ? 

I am frustrated as to what would cause multiple outbreaks in my system, and it seems like there is a lot of discussion on possible cures/treatments and clinical trials here.  I just want a simple thread to compare and contrast.

Thank you in advance.

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Opinion is just that - opinion.  Even with those who are scientifically inclined, at this point, everything is up in the air with respect to HSV and potential treatments.  Only when and if they work can it be determined successful.

Check out the wikipedia page for more information regarding the vaccines https://en.wikipedia.org/wiki/Herpes_simplex_research

The ones who are furthest along are Genocea and Admedus respectively.  GEN-001 has data showing results, Admedus should be out within the next while.  Halford, Albert Einstein and HSV-529 have insufficient data to say one way or another.  The only way to know for sure is to test them and your guess is as good as everyone elses'.  Herpes isn't simple, nor are the discussions surrounding potential treatments.  Good luck.

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well, if you read enough of what everyone says about the therapeutic vaccines then you'll get a pretty good idea of how effective they are...   They've been putting those vaccines out in the markets for years and people have gone to Russia (they have an HSV vaccine), Italy (they have another) and have all have un-inspiring feedback.  

Fast-forward now, genocea's work.  Reading the various people reporting on Genocea is interesting.  First off, genocea has been doing their trials for a while now.  If they weren't making some positive impact then I don't think they'd still be running with it.   But I've read quite a few reports of people saying it's awesome and their outbreaks are nill and others who experience a slew of painful and uncomfortable symptoms that make them regret getting the therapeutic.  I imagine the vaccine primed the immune system to digest a piece of the person... their nerve or whatnot.  they always complain of nerve pain.   But I don't know what the doses people receive and genocea is testing a variety of doses throughout these trials.  My impression is that the very robust people have the material/bodily essence to support an immune response and clean up the virus per catalyzed by the vaccine.   People who are constitutionally weaker will not be happy with their results because while they have the a little substance on standby to be called upon by a therapeutic, their rate of repair and maintenance might be very low.

This is the same feedback I've observed from several of the past therapeutics to now.   It was something I didn't want to believe but honestly, it's a reality of life that is centered around a vital essence.

I'm excited to see what Admedus does.  I'd love for this trend to be proven wrong but if you're not removing the root cause of the problem then the body is still fighting a chronic viral infection, therapeutic vaccine or not.

Those other vaccines might be great for people who don't already have the virus and protect them from contracting it.  That'd be wonderful news for everyone.  ...Maybe not the Earth though, bc our bastard selves will live longer and rape her resources a bit more.

So CRISPR...   I read a paper on CRISPR eliminating 84% of a gene in a mouse's eye.   There's another how CRISPR affected the brain stem of a pig.  Cullen and Bloom are presently doing live rat studies for HSV-1 and the results for that will happen any time within the next few months.  CRISPR is the only method that actually removes the virus.  That mean no more virus absorbing your vital resources and no more of your body relentlessly producing antibodies, digesting and removing viral debris.  I'd like to get excited... Partly, I am... But I know better.  It's like getting excited for the results of the next two olympic games.


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