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Agenovir Corporation-CRISPR/cas9 for Latent Viruses


JustHanginginThere

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And the race for CRISPR/Cas9 therpeutics (which could result in cures) continues......I know these guys have a grant for EBV, but I don't know what other viruses they are working on right now.  If anyone knows, please inform the group. 

 

 

Agenovir Corporation

South San Francisco, California

 

Agenovir’s mission is to develop innovative anti-viral therapeutics that will improve clinical outcomes of patients with diseases caused by latent or persistent viral reservoirs. Agenovir’s core technology platform, originally from the laboratory of Dr. Stephen Quake of Stanford University, harnesses novel nucleases such as CRISPR/cas9 for the treatment of disease. We recently closed our Series A financing and we seek motivated, talented, and resourceful scientists with a minimum of 2 to 4 years of postdoctoral and/or industry experience, who possess an entrepreneurial and collaborative spirit and embrace our mission. A successful applicant will independently design, implement, and troubleshoot experiments and effectively present results and research plans. Depending on experience, the candidate may lead other scientists to support projects across research and into early development, including acting as a member of a multidisciplinary project team.

 

 

Edited by JustHanginginThere
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HO-LEE-MAC-AH-RONI!!!

EBV!!!!   So this is retroviral territory now!!!  albeit, EBV is a herpesvirus, it does reverse-transcribe itself into it's host.

omg, I'm going to cry (joyously) if there's a therapeutic to clip out retroviral EBV.

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  • 3 months later...
11 hours ago, LillianPanos said:

Sanguine108 tell us more!

What Sanguine108 was excited about was the fact that EBV is a retrovirus which is the same type of virus as HIV. As we all know HIV is a awfully difficult virus to treat, so if they were to be able to cure EBV then the next logical step would be to attempt to cure HIV once and for all. Also IMO, HSV would be a lot easier to cure than EBV. HSV is found outside the cell nucleus.

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14 minutes ago, dont quit! said:

What Sanguine108 was excited about was the fact that EBV is a retrovirus which is the same type of virus as HIV. As we all know HIV is a awfully difficult virus to treat, so if they were to be able to cure EBV then the next logical step would be to attempt to cure HIV once and for all. Also IMO, HSV would be a lot easier to cure than EBV. HSV is found outside the cell nucleus.

This is great news!! What timeline are we looking at?

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  • 1 year later...

thanks for sharing, i see they are currently not looking at HSV however may be a breakthrough they have may help someone else. lets hope they share learnings from research. 

 

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2 hours ago, JJ2017 said:

thanks for sharing, i see they are currently not looking at HSV however may be a breakthrough they have may help someone else. lets hope they share learnings from research. 

 

They mentioned herpes simplex

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2 hours ago, moialbalushi said:

They mentioned herpes simplex

They said the technology can be used for herpes simples virus, they list what they are working on a few sentences down. 

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1 hour ago, JJ2017 said:

ping them a mail, im not sure if im missing something but i cant see where they say they are working on HSV

I already did send them before. But no reply yet

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