The Definitive Link between HSV and Accelerated Cognitive Decline is Almost Certainly Coming

[StayingUpbeat]

In my first (and only) visit to a live herpes support group the dermatologist running the group mentioned that on the day or two before she has a coldsore she cancels all of her surgeries because she starts to get (in her words) "a bit loopy."  Studies by progressively more respectable doctors in progressively more notable journals are showing up every few months linking greater severity in age related cognitive issues with chronic herpesvirus infections. 

http://www.newsmax.com/Health/Brain-Health/herpes-cognitive-decline-virus/2016/02/09/id/713500/

Much like the lucky strike generation of soldiers coming home from WWII definitively exposed the link between smoking and cancer in the 50's the tinder generation of the 2000's is (in my opinion) going to definitely expose this reality.

If only we could quit Herpes

Edited February 17, 2016 by StayingUpbeat

[blistering love]

That's depressing, but if we got dementia would we forget that we had herpes, or would it just affect short term memory first? it already runs in my family..but i was hoping i'd be eighty before encountering it!

[Sanguine108]

Yeah, it's no joke.  I've definitely felt different over the past 9 months.  Days I wake up and my hearing is dim.  I'll do my meditation and tai chi practice and keep feel coolness of blood circulating in my head, which is cool.  ...but I never noticed that before this...

For one, the virus is constantly using resources of the host, both proteins and lipids. Nervous tissues is nourished by lipids, so nourish your nerves.   Then there's the resources that the hosts immune system uses to fight/suppress the virus.

alzheimers and all these neurodegenerative conditions are essentially the brain/CNS drying up.  

But I think this is more of a problem for ppl who have oral herpes compared to genital.

dont get me wrong, resources are still being consumed, but further from the brain the better imo But it's all apart of the same nerve

Edited February 17, 2016 by Sanguine108

[WilsoInAus]

Can you please enlighten us as to what condition you are talking about? You don't have HSV!

Id have thought that St Johns Wart was actually doing something for you, but that appears not to be the case. Maybe you and all those you recommend it to should try something else? 

[Evaluate]

I would agree with this also. I wonder if mylanation also has something to do with it. I have both oral and genital h but my noticing the effects did not occur until months after acquiring genital h, so I do not necessarily support that hypothesis, sangenuine. I'm curious as to know how the brain is affected; the entire brain, a specific part, etc. I wonder if one of the two vaccines furthest along would provide good relief for this. My feeling is that neuroplasticity is an amazing thing. I hope that this is true with h.

Edited February 17, 2016 by Evaluate

[lexyz22]

I think this is almost exclusively HSV-1 though. In my opinion it doesn't make logical sense to link a Genital Skin Condition (HSV-2 for example) to Cognitive Decline or Mental Illness. 

I have felt perfectly normal since getting HSV-2.... apart from my Dick, but thats because it only affects my Dick, and not my Brain. 

Genital HSV doesn't even work along the same nerve pathways anywhere near the brain (sacral ganglion), so im not worried personally.

My Nan had Coldsores and she was fine until the day she died (aged 95), so that theory doesn't apply to my Nan, who also smoked a lot too (she never got cancer either by the way). 

You're forgetting that the "Tinder" generation will most likely have a functional cure within the next 5-10 years anyway. 

Also, 2/3rds of the worlds population has Herpes, and there is no studies saying that 2/3rds of the world population has mental illness.

Sorry man but i think this is all bullshit.

[fixme1]

Great , mental illness on top of it.

hsv 1/2 isnt routinely tested why ? oh ye... they say its not a big issue.

Tinder generation? I assume you mean cause of all this technology it is aboloshing people wanting relationships and making it all about one thing. I can say that tinder is used alot and joked about alot for it. shame in the Uk hsv isnt well educated about, im sure its on the uprise in the uk. but stastistics say other wise (i dont believe them) and if its gonna cause mental illness then why are they ignoring educating it

 

[Sanguine108]

Everyone is different.  But we can't forget that everything is connected.  sure, for someone who has o-hsv, it may be closer to home.  ...In the clinical setting, the people I've seen with oral hsv vs gHSV are, for sure, different.   

I'm implying that viral replication competes for the host's resources.  That is, amino acids and lipids.   Nerve tissue is considered healthiest with a healthy amount of lipids.  Fats are brain and nervous system food.

As for affecting different parts of the brain... Well, I'm only going to speak from personal experience.  The first week of symptoms (before breaking out) I felt like my head was caged.  I felt warmly caged and malaise. I thought wow, this must be what encephalitis feels like at very low level.   Later, I connected that caged feeling was the trigeminal nerve. ... parasite

So yeah, St. John's Wort does help but I understand it's not for everyone.   SJW has been shown to increase the diameter of nervous tissue, as in it regenerates nervous tissue.   And SJW has been shown to reverse amyloid plaque formation, thereby staving off 'alzheimers'.  Like anything, people should be under the guidance of a practitioner who can treat the root and the manifestation of how a person presents   I alternate between a few things.  But one thing is for sure, nerves are the target.

Regardless of my terse explanations there's always recent research publications on it.

Herpes simplex virus type 2 infection induces AD-like neurodegeneration markers in human neuroblastoma cells. (2015 - Journal of Neurobiology of Aging)  
http://www.ncbi.nlm.nih.gov/pubmed/26163986

Herpes simplex infection and the risk of Alzheimer's disease: A nested case-control study. (2015 - Journal of the Alzheimer's Association)
http://www.ncbi.nlm.nih.gov/pubmed/25304990

Reduced Alzheimer's disease pathology by St. John's Wort treatment is independent of hyperforin and facilitated by ABCC1 and microglia activation in mice.  (2013 - Another Alzheimer's journal)
http://www.ncbi.nlm.nih.gov/pubmed/24156265

I'm not trying to be alarmist on all this but in light of the thread topic, I love talking about pathophysiology.

[lexyz22]

This is what I didn't want to happen. 

@fixme1, there is no clearly defined CAUSAL link between any type of Herpes and Mental Illness, there just isn't. 

Sanguine has posted a thread based on a couple of studies he has read, none of which state a definitive link between Herpes and Mental Illness, only correlational effect. 

Sanguine, you need to realise that whilst researching links like this is interesting, it can spark the fear of God in people and you know aswell as I do on these forums, there are MANY people who are not mentally stable and/or contemplating suicide. I'm not saying you will contribute towards this in a negative way, but looking at this thread objectively, you can easily see how a mentally-weak person could read this and think "Oh fuck this, not only do i have outbreaks, but now im going crazy too....fuck my life"

Anyway im not trying to get into an argument or anything, but until there is definitive proof that A + B = C, I'd refrain from posting things like this unless its positive, aka: Vaccine or Drug Successes etc. The vaccines coming out will no doubt reduce viral latency and thus any mental side effects IF that was even the case, which it hasnt been proven in humans at all.

 

[fixme1]

Im one of them mentally  unstable people, but im not reading into it as there is no proved studies of it and my common sense comes in and thinks... anything can be wrong on the internet (its like googling something and its always negative),  Its just ideas i assume.

[WilsoInAus]

It is all just bunkum! The press just generate these stories out of crappy PhD and similar studies. They are designed to detract from the real issues of world poverty, violence in communities, bankrupt European countries, social fabric breakdown with the aging population, ongoing oppression of minorities...

[Sanguine108]

@lexyz22

I agree with you on considering the audience.  Talking about this aspect of herpes isn't really what I like to focus on.   It's just that the whole PR on herpes annoys me.  I remember watching an interview with a researcher and the journalist asked why this herpes research was important and the researcher said something to the extent of, "Well, it affects people's sex lives and that is a hard blow to anyone self-esteem."  I was waiting for some REAL answer but that was his response.   Anyhow... I'll just be patient.

I'm glad we can agree with that.

But one last photo for the road.

Edited February 18, 2016 by Sanguine108

[lexyz22]

Hey Sanguine,

I spoke to a leading researcher in HSV today via Skype, and as soon as I mentioned this he basically said it was bullshit. 

This is someone mentioned alot on the forums, but whom I cant really state his name (even though it makes my argument seem weak). 

Apparently the NIH and other bodies publish research relating to mental illness and only look at CORRELATIONAL effects, so out of 100 elderly people who have dementia, if 40 of them have coldsores, this is drawn upon as a correlate, not a causational factor. 

I'm not trying to argue here, but If a leading researcher in HSV (30+ years) says its BS, it probably is my friend.

[Sanguine108]

Yeah, again, I'd believe a clinician over a bench work scientist.  Te top heart-nutrition-cardio researcher will say there's a correlation between cholesterol intake and heart attack/plaque buildup.  Go over to the heart surgeon and with all the heart attack patients they're expecting all this plaque buildup but they find nothing to correlate the 2.   

I'm not convinced especially when experiencing my friends, collegues, patients, ppl on this board and fbk who have hsv. It's not immediately clear online but in person there's no doubt.

it was just mysterious at first but it's clear to me now.  

I'm fine playing along w ignorance is bliss but asking a real expert who actually is dealing w the population, who doesn't see patients for less than 10min and doesn't just gather their information via statistics is a much more realistic and pragmatic approach.

plus, sample size of 1 researcher's opinion is not enough to make a statistically significant conclusion.  3+ is the number for things to be considered stats worthy.

Also, he may think it's nonsense bc he hasn't read how recent the publications are (2015).

[SureWhyNot]

Lets all talk about this again in 30 yrs and see what we have to say! Oh wait, I will have forgotten about this site because I will have had HSV 65 yrs, but then my memory loss will be old age, right!

There are so many aspects to this virus nothing can be dismissed across the board as each person is so individual. Some may not notice the cognitive loss! Those of us who considered ourselves sharp can feel the difference. There are spaces in my thought and learning patterns that were not there before but again since I am 60 now that is normal, right. I am dealing with medical issues that allow sacral outbreaks, something new to me, and days before one surfaces I feel thick as a brick or really scared, (I really like that one) and just go with the flow of the day as it is easier than thinking. Anyone else getting sacral outbreaks from eating fruit and vegetables or is that my nonsense?

If everyone throws what we know into the information pool there will still be unanswered questions so why would we negate a possible link that could help someone? I believe everything has validity even if only on a personal level. You be you, I'll be Me!

 

 

[dont quit!]

Although there may be correlation between HSV and cognitive decline. There still isn't obvious, clear cut proof. Factors age related, stress, anxiety and just "life" really take a toll on ones body. Many are depressed just for bring infected with an incurable, stigmatized infection. That factor  alone may cause a cognitive decline. Too much stress on the system will screw up anyone; HSV or not.

[lexyz22]

If 2/3rds of the Worlds Population has Herpes, then researchers better get producing some anti HSV-ALZHEIMERS-DEMENTIA superdrug, otherwise we are all fucked basically. #sarcasm

But obviously thats not the case as nothing has been proven yet, at all.

[Herbfresh]

Well HSV does kill people, cooks their brains, encephalitis. So obviously to can cause the early onset of mental decline and diseases. 

When my progdrom gets very bad many times it makes me sweat a lot. Like my face is burning. Its quite common. Hasn't happened in a long time and it seemed to be happen quite a bit for a year. 

But yea, if you have a mutation of certain gene, HSV will increase your chance of alzheimers like 3 fold. And perhaps it increases the chances for everyone. Most likely it does for all sorts of things. But it also depends a lot on how much the virus afflicts one. 

For some people the virus remains in check virtually all the time, so it would do much less damage. But, yea, HSV also ages us more quickly, wearing out tellurides so it only stands that it would accelerate the onset of mental diseases, especially since HSV directly attacks the brain. 

Edited February 19, 2016 by Herbfresh

[Sanguine108]

Apparently Hillary has an understanding of Alzheimer's.   

VOTE FOR ST. JOHN!!!

[WilsoInAus]

This is all just bunkum. Every year some scientist trots out the HSV-1 link to Alzheimer's and it hasn't been proven in over a 100 years of trying.

There was a massive scare in the 1950-70s over this when the spotlight really turned onto Alzheimers with longevity starting to accelerate.

Many scientists came out with the theory and claimed they had proved it. However other scientists proved them wrong and found a much stronger correlation... aluminium pots and pans!!!

Despite the much, much stronger correlation, even aluminium pots and pans is considered a myth today. HSV-1 is well behind.

 

[lexyz22]

2 hours ago, WilsoInAus said:

This is all just bunkum. Every year some scientist trots out the HSV-1 link to Alzheimer's and it hasn't been proven in over a 100 years of trying.

There was a massive scare in the 1950-70s over this when the spotlight really turned onto Alzheimers with longevity starting to accelerate.

Many scientists came out with the theory and claimed they had proved it. However other scientists proved them wrong and found a much stronger correlation... aluminium pots and pans!!!

Despite the much, much stronger correlation, even aluminium pots and pans is considered a myth today. HSV-1 is well behind.

 

Thanks, this x1000.