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Rational Vaxxer

The vaccine for herpes. The id and the ego

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Rational Vaxxer

 We have all heard the proverbial sales pitch in regards to relieving symptoms or even some products claims to “Cure Herpes.” For me, I have seen and read ads ad nauseam for almost 30 years. This instant Snake oil that can or will be considered a cure seems like a good idea at the time.. You spend hundreds, if not thousands of dollars in desperation to get relief, only for the endeavor to end tragically at the bottom of the cliff of disappointment. This does not come without a mountain of buyers remorse. These events have left many empty and not without an awful taste in their mouths.

If I may be crass, It’s not much different from dating a bunch of assholes your entire life and every experience ends the same. Sad and empty. For many years this was my experience with many attempts to find relief from this Herpetic disease. The countless hours and money wasted is just too much of a burden to grant it any more thought or remembrance.

 This story however, has a happy ending. This solution I thought was too good to be true, actually worked. I received the vaccine for HSV2 from my friends at Rational Vaccines, as a trial participant in phase 1. Honestly I have tried everything under the sun and this was the only relief I ever received. 

After the public press release of the trial information, I was granted permission to talk about my experiences in public. I knew there would be doubters and haters but I was surprised at the anger I received from some of the people I called friends, who frequent in the social herpes communities. I was called a bull shitter, liar and threatened ( cleverly I might ad ) to a fight in order to kick my ass for giving false hope. In the end, I am not worried about telephone tough guys or keyboard bullies who talk a tough game online, but in person, they say nothing. The reactions were very interesting non the less. It is interesting to me that some who suffer from an ailment for an extended period of time begin to become a victim of its grasp and this disease becomes part of their personality. It becomes about them, their life and their very being. In a way, a slave to ones captor, a sort of Stockholm syndrome.[1]  I wouldn’t be as so bold to say this is a great comparison, but its just for relation to the topic and discussion and of course, I am not saying this affects everyone. It was intriguing to me that a vaccine, that may be a therapeutic cure, would be so threatening towards a person. That is unless it threatened who they are or who they have become.

This is just an opinion, that some who succumb to the hard grasp of this disease, can not help the end result of being consumed buy it. In the end, they are simply doing the best they can. They are in a struggle that is hard to win and one that is hard to accept. I know this because I lived it for over 25 years and many moments in great pain. 

When I spoke about the vaccine and how relieved I was, the expectation of doubt should have been automatic and expected. Even though I was met with a few disbelievers and haters, I can’t say I could blame them for being skeptical. If I was on the other side, would I be the same way? Would it be just as easy to say “ Its bull shit?” I would like to think that my love of science would allow me to be more open minded but I have to be honest. If I heard someone say they received a vaccine for herpes, that not only relieved all of their symptoms but they no longer had outbreaks, I would probably say something similar to “ that has to be bull shit!” 

Looking back, it’s very troubling to me that I allowed this disease to become a part of who I was and part of my personality, instead of it just being a nuisance. It would seem that the infection in my body, also infected my personality and became a major part of what I identified with. It didn’t just infect my cellular structure, it infected my Id and my ego. It seems I was not that much different from the haters after all. we both share the same issues but with different responses. HSV didn’t just change our lives, It also changed who were are.

The good news is every new day is an opportunity to learn and grow from the past and reflections of new ideas. This experience with Rational Vaccines has been a game changer and It is my hope that many will feel as good as I do from this experience.This vaccine didn’t just give me my health back, it gave me my life back and gave my ME back. 

 

 

[1] Stockholm syndrome, or capture-bonding, is a psychological phenomenon first described in 1973 in which hostagesexpress empathy and sympathy and have positive feelings toward their captors.

 
 

 

 

 

http://rational-vaxxer.tumblr.com/post/152091625458/the-vaccine-for-herpes-the-id-and-the-ego

Edited by Rational Vaxxer
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Hansje

Rational Vaxxer thank you for your message. It brings tears of happiness to my eyes. How great you must feel after so many years of suffering. 

Many of us here wonder about shedding. Is it too early to ask? Can you tell anything about that?

Enjoy your new life! And thank you for sharing here!

 

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Seeker1960

Hi @Rational Vaxxer thank you for confirming the results of how effective the vaccine really is. I post occasionally on another support site where the owner of the site wont allow discussion of vaccine trials and especially Halford's. He is under the impression that Halford is using "bad" science. So there are many people who dont even know what is developing or are the false hope stuff is being propagated. 

My money has been Halford for the last many months. I just can't believe how much progress has been made in the short time I have been following this! It is amazing!

Your testimony gives everyone here hope and encouragement that we will experience the relief of symptoms that you are experiencing in the near furture. Halford is shooting for a year to deliver a product out there and I can't wait for that day to get here.

All the best to you! Thanks for sharing!

Edited by Seeker1960

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TCBH

Thank you @Rational Vaxxer for sharing your experience.  I am so happy you have found relief and so sorry for all the haters.  It's good that you can empathize with their mentality and shows great emotional intelligence on your part.  Correct me if I'm wrong, people don't understand that Halford probably would have gone a more traditional route to get his vaccine through the FDA and to market but the powers-that-be have been leaning towards sub-unit vaccines over his approach of a live attenuated vaccine so funding has been difficult.  I think we're very lucky this has happened this way though.  Getting a vaccine through FDA takes many years but with this sidestep hopefully many of us can receive the therapeutic vaccine next year!  Thanks again and I hope you will keep us posted on your journey.  :-)

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agamemnus

@TCBH

Admedus is developing a vaccine based on a live attenuated virus. Genocea is much closer to a product than anyone else, with its sub-unit vaccine currently in P2B trials. As far as I have read, sub-unit vaccines have two advantages over live attenuated viruses:

1) The advantage of safety -- there is no chance that sub-unit vaccines can somehow mutate.

2) The advantage of cost of production. Theoretically, they are much, much, much cheaper to mass-produce.

Genocea has a product launch slated for 2020. That is far away. However, Genocea has stated that they will enroll a very large number of people for its Phase 3 trial. It is set to begin enrolling in mid-2017.

Edited by agamemnus

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Seeker1960
1 hour ago, agamemnus said:

@TCBH

Admedus is developing a vaccine based on a live attenuated virus. Genocea is much closer to a product than anyone else, with its sub-unit vaccine currently in P2B trials. As far as I have read, sub-unit vaccines have two advantages over live attenuated viruses:

1) The advantage of safety -- there is no chance that sub-unit vaccines can somehow mutate.

2) The advantage of cost of production. Theoretically, they are much, much, much cheaper to mass-produce.

Genocea has a product launch slated for 2020. That is far away. However, Genocea has stated that they will enroll a very large number of people for its Phase 3 trial. It is set to begin enrolling in mid-2017.

I guess you wont be signing up for Halford's trials. If Theravax becomes availble next year are you going to wait for 2020?

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StayingUpbeat

Admedus's offering is also a gD2 subunit vaccine not a live attenuated.  There are only 3 live attenuated HSV vaccines in the pipeline that I know of (2 of which are in human clinical trials)

  • Rational Vaccines Prophavax HSV2
    • ICP0 Deletion mutant
  • Sanofi Pasteur HSV-529
    • UL5 and 29 deletion mutant
  • Albert Einstein Medical Center (unnamed)
    • I can't recall the gene they deleted but it the virus doesn't produce surface protein gD2

All of the others I know of, including and especially the Admedus vaccine, are either DNA subunit (Admedus, Vical) or Protein subunit (Genocea, Agenus, most others).  All of the vaccines mentioned include the gD2 protein (or the DNA to encode it) though some also include a few other genes/proteins (Vical and Genocea specifically).

Edited by StayingUpbeat

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agamemnus

@StayingUpbeat:

Ah, ok. Thanks for that correction and mentioning these other two.

 

@Seeker1960:

Well, Theravax won't be available next year, in the United States. And 2a/2b trials have historically been very small -- the last Theravax trial had only a few dozen patients. Even if Theravax becomes commercially available somewhere outside the US, the price tag will likely be in the tens of thousands of dollars, since the production of the vaccine isn't on a commercial scale.

Even the protein-based vaccine that Genocea is trialing will likely cost several dozen thousand per subject for several thousand patients -- though it is free for the subjects, obviously. (note: various outside estimates for the final price are $250-$400 per year)

Edited by agamemnus

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Hansje

Tens of thousands of dollars? Ok it is out of my reach. This is a big dissappointment.

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LucyLevi

No Halford has told someone on here $2000

Not sure where tens of thousands have come from but that certainly would be a cure for the elite

Lucy

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Hansje

OK. I counted on 5000 and started saving especially for next year, since October 13th.

2000 would be even better!

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agamemnus

$2000, at what scale? Just consider that Genocea is using a significant multinational company (FUJIFILM Diosynth Biotechnologies) to produce their vaccine, which is supposed to be cheaper than attenuated virus vaccines.

Edited by agamemnus

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LucyLevi

Hi agamemus

So its great news then... lots of potential options hurray!

Lucy

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agamemnus

Yeah, I think so. I am really excited by Genocea's prospects but others are starting to show some better results than in the past as well.

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  • Posts

    • StayingUpbeat
      It should be noted that the Gates foundation was part of a venture capital group that gave Genocea $30 million in support of their vaccine development efforts in the period when their lead candidate was an HSV-2 therapeutic vaccine (GEN-003): https://xconomy.com/boston/2012/10/10/genocea-snags-30m-from-gates-foundation-vcs-for-new-vaccines/ They have also provided 30 million dollars to the University of Washington's HSV efforts.  This time specifically on research into whether suppressing HSV results in a reduction in HIV transmission: https://honeycomb.click/topic/77503-donations-to-fred-hutch-center/page/21/?tab=comments#comment-493474  Far from inactive in HSV research they provide significant funding in the context of reducing HIV transmission.  It's a well established fact that genital HSV greatly increases the probably contracting HIV from an infected partner.
    • Cas9
      Human trials starting next year?  Not even close. It will be several years.
    • hunger4more
      Sounds like X-vaxs' biggest concern is prevention and erradication secondary..... 🤦🏻‍♂️
    • IAmDesperate
      Ahh thank you for the link, but sadly I have HSV1
    • Pitchbird
      It may be small scale but at least it shows me that I'm by far not the only one who isn't willing to disclose to casual partners anymore. The damage for oneself is too high to make it worth it imho: - seduction becomes difficult as guy if they know in advance - you're very likely to become a gossip object if it happens within your social circle - you get abandoned before it even starts to get intense - you end up lonely and depressed after being abandoned for such a reason Still, that doesn't answer the question if it's better to disclose properly out of nowhere during the relationship or wait for the symptoms to appear and pretend to be surprised and fake the doctor diagnosis afterwards. At the moment I think the true disclosure would be less likely to be accepted by the partner, but in case it works it would feel better in the end because there's less of a secret kept in the long run... and of course there's lower moral burden when disclosing earlier because you're handing over responsibility of risk exposure to the partner.
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