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Another potential herpes cure?


West end gal

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Ninguna., ni crisp cas9 ni Dr halford ni Dr bryan cullen ninguna de eso será una cura., lo que puede salir es algo que mejore los síntomas pero una cura no en nuestras vidas

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8 hours ago, West end gal said:

Hi @West end gal I posted about this drug on another thread  [link]: 

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What they used was a known HSP90 inhibitor (CCT018159) which is already being tried as a cancer treatment. CCT018159 causes diarrhea, fatigue, and the main problem is doubly that its quickly cleared from the body and has very low oral bioavailability. Meaning you'd need to take 40-100 pills of it a day to reach any decent HSV inhibition of replication in humans - such dosing would cause liver damage. I didn't check the analogues tested so unless they find one or I missed something in the research Pritelivir is far superior to this, safer and much closer to market...

Bottom line the study was a proof of concept..... potential? I didn't check the study closely for analogues of CCT018159 they tested for possibly having greater oral bioavailability but as it stands its so poor that its unlikely ever to reach human use.

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What a crock title.  For something so far away from market, let alone with such questionable feasibility, this is what gets people's hopes. Journalists ought to know better.

Edited by Evaluate
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5 hours ago, Evaluate said:

What a crock title.  For something so far away from market, let alone with such questionable feasibility, this is what gets people's hopes. Journalists ought to know better.

How do we know that this is not legit?

 

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1 hour ago, valleynovascotia said:

How do we know that this is not legit?

I'm not saying that the discovery isn't "legit" what I'm saying that calling it a potential cure at this stage is not only pre-mature but irresponsible to the readership.

Look at the title on a scientific-based news site http://phys.org/news/2016-11-protein-herpesvirus-rna.html and then compare that to the newspaper's title posted above.  While the article itself isn't misleading, they certainly went with a title that would get clicks and reads.  Is it a big deal?  No.  Is it honest?  No.

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Just now, Evaluate said:

I'm not saying that the discovery isn't "legit" what I'm saying that calling it a potential cure at this stage is not only pre-mature but irresponsible to the readership.

Look at the title on a scientific-based news site http://phys.org/news/2016-11-protein-herpesvirus-rna.html and then compare that to the newspaper's title posted above.  While the article itself isn't misleading, they certainly went with a title that would get clicks and reads.  Is it a big deal?  No.  Is it honest?  No.

Too bad I really want to be cured.

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Journalist and others kill me titling things like this and getting peoples hopes up. This is what causes people to be suicidal. I'm trying to come to grips with knowing I will never be cured.  

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En verdad esto es deprimente tanta gente sufriendo y no hay cura :( yo quisiera que se manifestarán contra el gobierno, :( no le puedes llamar vida a algo que te reprime e escuchado mucho sobre crisp cas9 y sobre el Dr halford pero aún no hay nada sobre la mesa aveces quisiera sólo dormir por que es la única forma de sentirme normal, relajado, y tener sueños 

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18 hours ago, hopeful Rylee said:

Journalist and others kill me titling things like this and getting peoples hopes up. This is what causes people to be suicidal. I'm trying to come to grips with knowing I will never be cured.  

Better treatment options will come before a cure does, but I'm confident one will come in this lifetime.  Treating such a common virus has huge financial potential that it continues to gain momentum from pharmacology.

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Yo no quiero opciones  de tratamiento yo quiero una cura mientras más opciones de tratamiento salgan a la venta una cura no veremos en nuestra  vida 

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10 hours ago, Sean123 said:

Well isn't a functional cure Halford's goal? I doubt it will functionally cure us but you never know and this is within our grasps.  A sterilizing cure I think would take at least 10-15 years if Crispr can do the job.

What makes you think Halfords vaccine will not be a functional cure

Just wondering if you have a basis for this or it's just your opinion. Personally I've only read positives about his vaccine and am trying to find something that says something negative.

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11 hours ago, Sean123 said:

Well isn't a functional cure Halford's goal? I doubt it will functionally cure us but you never know and this is within our grasps.  A sterilizing cure I think would take at least 10-15 years if Crispr can do the job.

Dude seriously!! Why do you have to be such an unbelievable skeptic? I am so tired of reading your negative posts on this forum. You are clearly somebody who has a negative personality and don't give me that "I'm just a realist" type nonsense. Look man, if you don't have something positive to say then don't say anything at all. Look where you are! This forum is full of people who are keeping a positive mindset about the likely possibility of a functional cure soon. You are contributing nothing to this only spreading your negativity like a virus in itself. And I'm not willing to go back and forth with you on this and debate whether your opinions are justified. Do you work in the field of pharmacology? Are you a biologist? Do you have any real experience in the world of virology? I didn't think so. I know this sounds like i am coming off very aggressive here and its not personal man, I just can't take your persistent negativity and I don't think its necessary. Good luck.   

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