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By WorryandSpot
Hi everyone,
I have noticed a very small crater on my penis, right next to the urethra opening. It's shallow, small and painless. There's not really any identifiable features other than it being a small indent, like literally the skin just dips down. There's nothing inside it, no pus or weeping or liquid. No 'top' to it. It appears reddish/pinkish, like the skin around it. It is not sore or painful to touch. I have had it 3 days.
Here are pictures: https://imgur.com/a/ywiFWeL - it's difficult to photo without it being somewhat lost.
I have to also say that I've had discomfort of the lower abdomen for a few weeks. I don't have pain while urinating but there's a general discomfort of the urethra. Not burning, but discomfort - around 2/10 in scale.
I have had this 'crater' or 'indent' come and go before. Maybe around 3 months ago, I remember it was around for a handful of days, and faded again. No scab or healing over, it just sort of faded.
So does this seem to correlate with a mild outbreak or recurrence? Can anyone point me in the right direction? Has anyone experienced anything similar?
Doctor's have been extremely slow to help. It's so hard to see someone without waiting weeks, and when I finally do they have little knowledge or barely any time. With many craters, the first answer is often syphilis, but I had that test done before and it came back negative. I haven't had sex since and was well within the test window. I last had sex around 18 months ago, unprotected. I haven't had a Herpes test before.
I know many of you help keep this website a source of valuable information and ease so many people's anxieties or confusion, thankyou to all of you for your time and work.
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By SafetyMan
Hello everyone,
First thankyou so much for taking the time to read/reply. I could use your help so badly.
I had sex unprotected one year ago. A week afterwards I had some itching of the foreskin so went to the doctor, and was advised it was Balanitis. I got some cream and it went away within a few days. Since then I had a full STI panel of Chlamydia, Gonhorrea, Syphilis, HIV, and Hepatitis - all negative. Last week I had sex with someone new. She was a virgin, and we used a condom. Now since then, for the last 6 days I have had burning down my urethra - not while peeing, but just in general. I went to the doctor and they advised that it could be more Balanitis, so I got more cream. However, the woman I slept with now has flu, enlarged lymph node in neck, and a sore throat. I have also noticed these tiny tiny bumps or marks near the opening of my penis (pictured). I am not sure if I have always had them or if I'm just seeing them now.
Would these show a year afterwards, right when I have sex again (and with a virgin, with a condom)? Are my symptoms in line with Herpes?
Thanks for your advice, there's not much info on the internet.
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By Ausguy44
Hi everyone
I was diagnosed with ghsv-1 about 6 years ago and id like to share my exprience with you in the hopes that you may see the light at the end of the tunnel.
When i was given my diagnosis i had only recently moved to a new town, come out to my family and stsrted dating. I was basically at the happiest point in my life and boy did that take a quick turn.
I had every awful symptom under the sun the worst being intense nerve pain in my thighs and constant pins and needles in my hands and feet for almost 2 years. I was convinced my dating life was over and for the first time in my life developed severe anxiety. I was convinced i had some other life threatening disease that the doctors hadnt picked up went through a plethora of blood test, scans and dr appointnents. Even my Gp admitted my immune system was having a severe reaction to the virus. I had swollen lymph nodes in my chest, armpits and groin and had to sleep with an ice pack many nights.
However, my turning point was when i decided i needed to get back out there and start dating again. I was having few outbreaks and regularly taking antivirals it was mainly the pain stopping me. My dr eventually prescribed me pregabalin which stopped most of my pain and i started to feel like myself again.
I started dating... and i dreaded that conversation...telling someone else what i had. But obviously being the right thing to do i always told my partner before any physical activity. Over the following two years i dated about 5 people. Not one had a negative reaction to my honesty. Infact it was often the opposite.. and all of those relationships ended for reasons other than me having this virus.
I have now been in a relationship for almost 2 years with an amazing person and barely ever have those symptoms anymore. I keep valacyclovir and pregabalin handy just incase but its so rare i need them that i probably fill one prescription a year.
I used this forum daily for those first couple of years and never saw enough accounts from people once they got through that tough patch. I promised myself thst if i felt better one day id post ky experience. I know everybodys experience is different with the virus but i hope that this helps at least a couple of people see that you can and will one day feel ok, adjust to living with the virus and eventually feel normal again.
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By Jensport
Please join us Sept 1 @ 8PM PT / 9PM MT / 10PM CT / 11PM ET for a live Q&A session with national expert, nurse practitioner Terri Warren, RN, ANP. More details about the event are in the link below, where you may also post your questions ahead of time. https://www.reddit.com/r/HerpesCureResearch/comments/pbdbfw/qa_with_terri_warren_rn_anp_september_1st_2021/?utm_source=share&utm_medium=web2x&context=3
Warren has been in practice for over 20 years. She specializes in the Herpes Simplex Virus (HSV) and has served as principal investigator or sub-investigator on more than 120 clinical trials evaluating testing mechanisms for STIs, efficacy for experimental Herpes vaccines, and pharmacologic interventions for numerous human infections, primarily HSV.
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By Oops97
Had unprotected sex like 2-3 months ago. For a long time nothing came up. The I saw bumps appear between my thighs, thought it was razor bumps. Then my skin started shedding a lot, kinda like when kids cover their hand in glue and peel it off if that makes sense. I scratched/picked at some of them (and those were the only ones that “popped” and they were like open sores. Now they just go through this cycle of scabbing the the scab gets peeled off by my clothes or whatever and it starts all over. They don’t hurt, it tingled here or there, and I wouldn’t say it’s itchy but I’ve had the urge to scratch around it recently but I wouldn’t say it was often. And something similar formed on my elbow. I’m trying to get in to get tested ASAP but it’s hard. Any help? Input?
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Is this herpes? Facial bumps that won't go away
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By BabyGirl · Posted
I just stared dating someone who does not have HSV.How long after the sore is healed should I wait before having sex? I’ve had HSV2 for over 10 years. I rarely have outbreaks going months even years until recently. When I do I get some tingles and one sore in the same spot. But recently, In the last 3 months it’s happened twice. 🤦🏼♀️ -
By JDMT_176 · Posted
If you want to know whats going on when applying it, this was the only study I found describing it. Hard to read through as very technical, but am copy paste parts I found of use. Tables also useful to show which genes are expressed more. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416766/ "A petrolatum donut was applied with a cotton swab to form about a 1 cm diameter donut on skin on the inner aspect of the upper arm. Then a separate cotton swab was dipped in a 2% SADBE solution (w/v) in DMSO, and the swab was then used to apply about 10–20 mg of solution over about a 1 cm diameter circle within the petrolatum donut. Immediately after application, the application site was covered with TEGADERM. Subjects were advised to remove the TEGADERM and rinse and wipe the spot 3 h later. "Thus in essentially every case, the SADBE treatment changed the group A subjects by day 57 to make them much more like the group B and C subjects who have better immune control of their HSV‐1 infection than the group A subjects were on day 1. "Others have previously shown that CD8+ T cells are important in controlling herpes labialis outbreaks.23, 24, 25, 26, 27, 28, 29, 30, 31, 32 Our data are consistent with this. The helper/cytotoxic cell ratio (CD4+/CD8+ ratio) was 5.25 in group A versus 3.07 and 3.15, respectively in groups B and C (Table (Table3).3). The P‐value is less than 0.20 for comparisons of group A to both groups B and C, and if groups B and C are pooled and compared to group A the P‐value is 0.065, almost significant. This is consistent with prior evidence discussed below that CD8+ T cells are important and effective in controlling HSV recurrences. "Consistent with our finding lower anti‐HSV‐1 IgG levels correlate with better control of HSV‐1 outbreaks, Spruance et al. also found lower serum anti‐HSV‐1 antibodies in HSV seropositive patients with a history of frequent herpes labialis than in seropositive persons with no history of herpes labialis.33 "Several prior reports also found IFN‐gamma to be important in controlling HSV infection and reducing HSV outbreaks. Dobbs et al28 showed that CD8+ T cells were able to clear an HSV‐2 infection in transgenic mice, but that efficacy was blocked in vivo by anti‐IFNG IgG. Liu et al31 showed that CD8+ T‐cells could prevent HSV‐1 reactivation from latency in excised trigeminal ganglia (TG), and that IFN‐gamma protein was produced by the CD8+ T cells, and that neutralization of IFN‐γ significantly enhanced the rate of HSV‐1 reactivation from latency in TG cultures. Spruance et al33 found that IFN‐gamma protein levels in PBMC supernatants stimulated with HSV‐1‐infected cell extracts were lower in frequent herpes labialis sufferers than HSV‐1 seropositive controls, consistent with the present result for IFNG gene expression in PBMC stimulated with heat‐killed HSV‐1. McKenna et al7 assayed IFN‐gamma in medium of PBMCs cultured in vitro and stimulated with inactivated HSV‐1 and found IFN‐gamma was at higher concentrations in medium of PBMCs from infrequent herpes labialis sufferers than frequent sufferers, also consistent with our findings. Cunningham et al34 showed higher interferon levels (including alpha, gamma, and lambda) in supernatants of PBMCs stimulated with heat‐killed HSV‐1 virus correlated with longer time to next herpes labialis recurrence. Carr et al35 showed that transgenic expression of IFNG could prevent HSV‐1 reactivation in a mouse model. -
By JDMT_176 · Posted
Hi Kurdt- I was thinking back in 2018-2019 there was several threads from viral frog that he was applying a 2% solution very frequently. Like several times a week. From what I gather- it didnt work for him at the time. I think too much applied caused immune chaos or something. The most recent Square X trial was terminated but this was the dosing frequency that was used in the trial below: I was planning on using Group C protocol. Group A is most frequent. Something to think about. https://clinicaltrials.gov/ct2/show/results/NCT03521479?term=squarex&draw=1&rank=4 Protocol: Arm/Group Title Group A Group B Group C Group D Arm/Group Description Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 2% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 0.5% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0, month 3, and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Adverse Reaction Table: Arm/Group Title Group A Group B Group C Group D Arm/Group Description: Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 2% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 0.5% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0, month 3, and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Overall Number of Participants Analyzed 10 10 10 10 Measure Type: Number Unit of Measure: events Localized reaction (rash, erythema, itching/pruritus, warmth/burning) at application site 24 14 17 6 Generalized adverse events (related, possible or greater) 2 3 1 0 Generalized adverse event (unrelated) 4 7 6 4 -
By Cas9 · Posted
No, it doesn't look like herpes at all. Why haven't you simply seen a dermatologist? -
By Neveragain99 · Posted
I've been having bumps appear on my face around my mouth for a couple years now. They usually take several weeks to disappear but these current lesions have been here for months now and don't seem to be healing at all. I've been applying salicylic acid and oil of oregano twice a week but am having no luck and it appears to be getting worst. This has completely destroyed my self esteem and I've given up on trying to date... I've attached an image if anyone could help me out with a diagnosis or some type of regiment to help make them go away i'd be forever indebted! Thanks
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