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Vical clinical trial

Sean123

By Sean123,
in Herpes Clinical Trials & Vaccines

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Sean123 Acknowledged Support Member

Sean123

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https://clinicaltrials.gov/ct2/show/NCT02837575?term=genital+herpes&rank=26

Detailed Description:

To evaluate the safety and efficacy of 4 doses of VCL-HB01, a therapeutic HSV plasmid DNA vaccine formulated with Vaxfectin in HSV-2-seropositive adults with a reported history of symptomatic genital herpes for at least one year.
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Second_chance Established Member

Second_chance

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The only thing I don't like about this trial is at the end of it if you received the placebo initially they don't give you the vaccine. Bummer! 

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Joseph_Esp Established Member

Joseph_Esp

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The only thing I don´t like about it is that this vaccine is pretty crappy. The reached 0 endpoints on the trials... Probably that´s why it seems so easy to sign up and go.

  • staypositivelivelife
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Second_chance Established Member

Second_chance

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3 hours ago, Joseph_Esp said:

The only thing I don´t like about it is that this vaccine is pretty crappy. The reached 0 endpoints on the trials... Probably that´s why it seems so easy to sign up and go.

Well I was denied because I'm short of having this stupid virus for a year by two months! 

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Joseph_Esp Established Member

Joseph_Esp

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2 hours ago, Second_chance said:

Well I was denied because I'm short of having this stupid virus for a year by two months! 

You missed nothing!

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    • EssenceL25
      Help me !!

      By EssenceL25 · Posted

      I’m going to force him to get tested ! Thanks for your help ! 
    • WilsoInAus
      Help me !!

      By WilsoInAus · Posted

      @EssenceL25 there really isn't a question mark around the source, it's your latest partner. The median time from infection to an outbreak of lesions upon initial infection is 4 days.  The only thing that isn't certain is the type I suggest.
    • EssenceL25
      Help me !!

      By EssenceL25 · Posted

      I asked if it was hsv 1 or 2 and the doctor said it was Hsv2. I’m not sure i just asked him when he was tested last he said this year I said I think we should go test together and he agreed . I’m going to bring it up again cause I really need to know if he gave this to me I wasn’t sure since it was so close to my previous relationship.
    • WilsoInAus
      Help me !!

      By WilsoInAus · Posted

      @EssenceL25 then it is all beyond reasonable doubt that the current partner is the source. A 'perfect' fit in terms of timing, symptoms and swab. It may be though that the type is not technically known. Culture swabs are very often not typed and just assumed to be HSV-2 if taken from a genital location. If you received oral sex in the days leading into 7 March then it is 50/50 as to whether this is HSV-1 or HSV-2. You could contact your doctor and confirm if the swab was actually typed (which is a second test where fluorescent antibodies for HSV-1 and HSV-2 are added and see which one 'glows').  If that test wasn't done then you do not know type. If you have oral HSV-1 yourself (cold sores) then this will be HSV-2. Does your partner have oral HSV-1? It is somewhat strange for him not to rush and test - many people have a 'reaction' if they truly do not know their status and have concerns that you infected them etc. (not initially rational of course). This indicates he may know his status - or maybe he just isn't simply the sharpest tool in the shed!?
    • EssenceL25
      Help me !!

      By EssenceL25 · Posted

      I had flu like symptoms and ulcers on my vagina . They did a culture and I tested positive for hsv2. I asked my partner to get tested he agreed but I’m not sure if he will cause he hasn’t said anything else about it. 
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