Anyone else feel like all these vaccines are just blowing smoke

[impugn]

All these promising vaccines but I don't think they will do what everyone wants them to do. We are still years away from a true functional cure, i.e. 0 symptoms, including 0 lesions, sores, etc and 0 chance of transmitting. I would even take just having 0 symptoms but still being able to transmit, if you did transmit it than your partner could also get the vaccine. 

This stuff is years away. Theravax looks the most promising for our time but it can still be a flop and mass sales won't happen for another 5 years if everything goes as planned. 

[Cas9]

15 minutes ago, impugn said:

All these promising vaccines but I don't think they will do what everyone wants them to do. We are still years away from a true functional cure, i.e. 0 symptoms, including 0 lesions, sores, etc and 0 chance of transmitting. I would even take just having 0 symptoms but still being able to transmit, if you did transmit it than your partner could also get the vaccine. 

This stuff is years away. Theravax looks the most promising for our time but it can still be a flop and mass sales won't happen for another 5 years if everything goes as planned. 

The headline for this thread and your comment have no real value. They are simply based on your unhappiness that you have herpes.

[impugn]

16 minutes ago, Cas9 said:

The headline for this thread and your comment have no real value. They are simply based on your unhappiness that you have herpes.

This is rant and rave... I'm ranting 

[Cas9]

Just now, impugn said:

This is rant and rave... I'm ranting 

I know; but you're making statements about the vaccines that have no basis in truth, which in turn is why you are ranting

[impugn]

1 minute ago, Cas9 said:

I know; but you're making statements about the vaccines that have no basis in truth, which in turn is why you are ranting

The only statement I made was that these vaccines are years away and that is the truth. Even if these vaccines do do what everyone wants them to do they have to go through trials and all that stuff which will take years. Even Theravax, if everything goes well it should be available in most likey Mexico in 5 years or less. Other than compassionate sales. I stated 1 opinion and 1 truth, no falses.

But you're right about me being unhappy about having herpes. 

 

[Hansje]

Well, you ask the question. I think not. I trust something good is really coming. Based on articles and based on my opinion that where there is hope there is life, and that giving up on hope (though very understandable and human) serves no purpose. 

[impugn]

11 minutes ago, Hansje said:

Well, you ask the question. I think not. I trust something good is really coming. Based on articles and based on my opinion that where there is hope there is life, and that giving up on hope (though very understandable and human) serves no purpose. 

For the past decades there has been a 'promising' herpes vaccine on the rise and none of them have made it yet and that is what makes me not want to get my hopes up.

But still if something good is coming, it will still take years to come. Theravax most likely won't be out for 5 years IF everything goes well. All the other vaccines will take 10 - 20 years to develop and progress through trials.

No one can sit around and wait for that. I don't mean to be a Debbie downer but it is the truth. 

[Cas9]

12 minutes ago, impugn said:

The only statement I made was that these vaccines are years away and that is the truth. Even if these vaccines do do what everyone wants them to do they have to go through trials and all that stuff which will take years. Even Theravax, if everything goes well it should be available in most likey Mexico in 5 years or less. Other than compassionate sales. I stated 1 opinion and 1 truth, no falses.

But you're right about me being unhappy about having herpes. 

 

You said that these vaccines are just blowing smoke. What you base that on is a mystery to me.
As far as being years away, of course, we already know that, it's right there in their pipelines. So what's your point? To tell us something we already know and that it makes you unhappy?

[Cas9]

1 minute ago, impugn said:

All the other vaccines will take 10 - 20 years to develop and progress through trials.

You have no idea what you're talking about. Instead of ranting and raving, how about educating yourself.

[impugn]

2 minutes ago, Cas9 said:

You said that these vaccines are just blowing smoke. What you base that on is a mystery to me.
As far as being years away, of course, we already know that, it's right there in their pipelines. So what's your point? To tell us something we already know and that it makes you unhappy?

Gen003, Vical, and Herp V

[Hansje]

4 minutes ago, impugn said:

For the past decades there has been a 'promising' herpes vaccine on the rise and none of them have made it yet and that is what makes me not want to get my hopes up.

But still if something good is coming, it will still take years to come. Theravax most likely won't be out for 5 years IF everything goes well. All the other vaccines will take 10 - 20 years to develop and progress through trials.

No one can sit around and wait for that. I don't mean to be a Debbie downer but it is the truth. 

Well, I don't sit around. I live a lot, work a lot, work out a lot, eat a lot (oops, should loose 3 kg really) and meanwhile the scientists are fighting herpes. 

There is not just one group, but many working on strategies against herpes. Like all scientific developments, things go faster every month. And don't forget the synergy. We might be in for a great surprise. Meanwhile, I do not sit around.

[Atrapasueños]

Tienes razón algunas investigaciones y vacunas están muy lejos, pero aún existen varias vacunas y crispr que se están moviendo en estos momentos recuerde que la hepatitis c no tiene vacuna pero el 90% de los casos ya se pueden  curar, se como se siente puede que exista ese pequeño tiempo donde alguien va curar el herpes o tal vez no pase no lo sabemos aqui lo que importa es cuanto tiempo va tardar

 

@impugnar You are right, some research and vaccines are very far, but there are still several vaccines and crispr that are moving at this time remember that hepatitis c has no vaccine but 90% of the cases can already be cured, as you feel you may There is that little time where someone is going to cure herpes or maybe it will not happen we do not know it here what matters is how long will it take

[impugn]

11 minutes ago, Cas9 said:

You have no idea what you're talking about. Instead of ranting and raving, how about educating yourself.

What? 10 - 20 years is the norm for vaccines. Actually 10 - 15 but that's still TEN to FIFTEEN years. Every source I read says 10 to 15. That's also why Theravax is taking place in St Kitts 

[Cas9]

Just now, impugn said:

Gen003, Vical, and Herp V

 

3 minutes ago, impugn said:

Gen003, Vical, and Herp V

Gen003 is not a failure so I don't know where you got that from. The other two (Vical and Herp V) are failures. And Gen003 starts phase III end of this year. Admedus has also been successful, so far. They will be announcing phase II results this month. That means, we don't know.

Theravax and HSV529 are in phase I, so we don't know what will happen with them either. Any vaccine that is in at least in phase I is not 10 -20 years away. A more accurate timeline would be 7 - 10 years, assuming that everything goes well.

The Einstein College vaccine is promising albeit it is in pre-clinical. That vaccine is probably around 10 years away.

[Cas9]

@impugn

Have you bothered to follow CRISPR? It is the best chance for a functional cure. Have you read about Excision Biotherapeutics?

[Cas9]

3 minutes ago, Cas9 said:

@impugn

Have you bothered to follow CRISPR? It is the best chance for a functional cure. Have you read about Excision Biotherapeutics?

And I forgot to mention HSV-2 Trivalent Vaccine which is also in pre-clinical.

[Mackie82]

There's no cure/ functional cure and no single vax is going to work I have spoken to people from all the trails , gen-003, admedus and Theravax so many of them got worse symptoms and some the vax did noting to them considering the placebo in few of them but believe me guys all bullshit. Back in 2012 they were saying AIC316,herpv and gen-003 is 3 years ahead hang in and we are in 2017 and 2 failed and the third one is expected in 2020 I assure you next year it will fail also , I am not being negative this is the fact you like it or not. Try the varivax (chickenpox) vaccine is better at least no harm I want anyone to answer this question . Since the same antiviral (valtrex) is used to treat HSV1,2 and 3 then why any vax can't be used for all of them the answer is because they want to keep selling the valtrex once any disease is causing death then they find the cure or the proper treatment at least otherwise we are left like the street dogs 

[Cas9]

7 minutes ago, Mackie82 said:

There's no cure/ functional cure and no single vax is going to work I have spoken to people from all the trails , gen-003, admedus and Theravax so many of them got worse symptoms and some the vax did noting to them considering the placebo in few of them but believe me guys all bullshit. Back in 2012 they were saying AIC316,herpv and gen-003 is 3 years ahead hang in and we are in 2017 and 2 failed and the third one is expected in 2020 I assure you next year it will fail also , I am not being negative this is the fact you like it or not. Try the varivax (chickenpox) vaccine is better at least no harm I want anyone to answer this question . Since the same antiviral (valtrex) is used to treat HSV1,2 and 3 then why any vax can't be used for all of them the answer is because they want to keep selling the valtrex once any disease is causing death then they find the cure or the proper treatment at least otherwise we are left like the street dogs 

I guess we'll have to agree to disagree. I'm not going to base the results on your comment. I'll wait for the results from the trials. Saying no single vax is going to work is not specific enough. The therapeutic vaccines are expected to help, not cure. The prophylactic vaccines are a different issue.

As far as your statement:
"Back in 2012 they were saying AIC316,herpv and gen-003 is 3 years ahead"
I have to question that comment. Show me where Gen-003 made that statement. And even if they did, all it means is that it took longer to do the trials due to funding or other issues. It's irrelevant. All we care about are the stats and the phase. They completed phase IIb and are gearing up for phase III 4th quarter of this year.

[Atrapasueños]

Entiendo lo que dice pero en otras enfermedades las vacunas han tenido éxito este virus es diferente es muy diferente a la varicela y una vacuna en ensayos puede tener reacciones ejemplo, no ser segura, no ser eficaz, empeorar la enfermedad, o controlar la enfermedad sin causar molestias lo que pasa en una vacuna es que estimula al sistema inmunológico para combatir la infección, pero ahora está crispr es nuevo pero crispr si es eficaz puede ir al problema de raíz si se llega a mutar el virus y hacerlo inservible

 

@Mackie82 I understand what it says but in other diseases vaccines have been successful this virus is different is very different from chickenpox and a vaccine in trials can have example reactions, not be sure, not be effective, worsen disease, or control disease without Cause discomfort what happens in a vaccine is that it stimulates the immune system to fight infection, but now it's crispr is new but crispr if it is effective can go to the root problem if it gets to mutate the virus and make it useless

[Cas9]

BTW, here's a press release on Gen003 April 11, 2017

http://ir.genocea.com/releasedetail.cfm?ReleaseID=1020901

Of course this doesn't mean Gen-003 will be a success; but it's certainly no reason to be pessimistic.

[Mackie82]

They are doing crisp in china for a lot of things, I know nothing about science and would like not to know but I do believe if the medical community really care then an effective and better treatment could be made valtrex is 21 yeas already do you believe in 21 years they could not do better pillls at least. BTW I know how the vaccines work and what they supposed to do for that body . Thanks 

[Atrapasueños]

Aquí lo que pasa es que es una enfermedad recurrente que no causa muerte masivas solo pocas y solo son molestias y dolor 

 

Here what happens is that it is a recurrent disease that does not cause massive death only few and only are discomfort and pain

[Mackie82]

7 minutes ago, Cas9 said:

I guess we'll have to agree to disagree. I'm not going to base the results on your comment. I'll wait for the results from the trials. Saying no single vax is going to work is not specific enough. The therapeutic vaccines are expected to help, not cure. The prophylactic vaccines are a different issue.

As far as your statement:
"Back in 2012 they were saying AIC316,herpv and gen-003 is 3 years ahead"
I have to question that comment. Show me where Gen-003 made that statement. And even if they did, all it means is that it took longer to do the trials due to funding or other issues. It's irrelevant. All we care about are the stats and the phase. They completed phase IIb and are gearing up for phase III 4th quarter of this year.

The phase 1 participant who got worse symptoms was told that the vax will be out 2015-2017 and I am not the one who's saying anyways prof. Ian Frazer said in 2012 admedus will be or at least he's aiming to be on the market in 2018 and not we r talking about phase 2 result is not yet announced phase 2 started in April /15 anyways as I know the vax mostly fail on phase 3 due to FDA approval and other issues. I am the most one who need and hope for any vax I spent the last 3 days reading the varivax result for the people who have taken it a lot of them stayed symptoms free for 1 years and above and some of them got worse symptoms and the rest the vax did nothing to them I believe this is the case for Theravax so far and you can make sure if you are in touch with anyone of the trial participant. There's also vitaherpavac in Russia which I am not sure about it if you could advise if you are aware of it. I am suffering the worst nerve issues and it's all HSV related . Thanks 

[Atrapasueños]

Le doy la razón hablan de tiempos y no pasa nada  dr cullen en 2009 dijo que en 10 años habría una cura faltan 2 años y ya no se sabe nada de su investigación, dicen que más vacunas no dura 10 años gen003 y amadeus van para los 10 años de investigación ensayos y resultados 

 

@Mackie82 I give the reason speak of times and nothing happens cullen dr in 2009 said that in 10 years there would be a cure missing 2 years and no longer know anything of their research, say that more vaccines do not last 10 years gen003 and amadeus go to 10 years of research trials and results

[Cas9]

2 minutes ago, Mackie82 said:

The phase 1 participant who got worse symptoms was told that the vax will be out 2015-2017 and I am not the one who's saying anyways prof. Ian Frazer said in 2012 admedus will be or at least he's aiming to be on the market in 2018 and not we r talking about phase 2 result is not yet announced phase 2 started in April /15 anyways as I know the vax mostly fail on phase 3 due to FDA approval and other issues. I am the most one who need and hope for any vax I spent the last 3 days reading the varivax result for the people who have taken it a lot of them stayed symptoms free for 1 years and above and some of them got worse symptoms and the rest the vax did nothing to them I believe this is the case for Theravax so far and you can make sure if you are in touch with anyone of the trial participant. There's also vitaherpavac in Russia which I am not sure about it if you could advise if you are aware of it. I am suffering the worst nerve issues and it's all HSV related . Thanks 

Sir; I don't care what a phase I participant said. Ad I don't care what a company said 3 years ago.
What I care about is the latest news. And the latest news does not jive with your comments. What we care about are the overall results. Is it possible that a particular participant may have had problems; sure. But that doesn't mean everyone did.

The latest news about Gen-003 is the link I posted. Admedus, also had good results but we can expect the final results for phase II, this month.

The bottom line is we should wait and hear what they have to say. These companies can't just make shit up; they are closely monitored by the FDA and require FDA approval before going to the next phase, and for gaining final approval.

The exception to the approval process is Theravax. I have no opinion on them one way or another.