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CRISPR Human Trials for HSV1/2?

CRISPR Human Trials for HSV2?  

247 members have voted

  1. 1. Latent HIV was recently eliminated in a murine model (mice) if the same or similar technology was applied to HSV1 and HSV2 would you be willing to become a human guinea pig and try it outside the Country?

    • No - Only FDA clinicals trials starting after the years 2030 with long term safety evidence
      2
    • No - Only FDA clinicals trials starting after the years 2040 with longer term safety evidence
      0
    • No - I don't care
      2
    • No - I'm waiting for live vaccines and may or may not do anything else
      5
    • No - I'm waiting for GEN-003/Admedus and may or may not do anything else
      2
    • No - I fear long term safety
      13
    • Yes - I'd do a Phase 1 and be in the first 10 people
      78
    • Yes - I'd do a Phase 1 and be in the first 10 people but only if asymptomatic measurements are taken (shedding)
      43
    • Yes - But I'd only do a Phase 2 or higher.
      102


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OFMDH

Latent HIV was recently eliminated in a murine model (mice) if the same or similar technology was applied to HSV1 and HSV2 would you be willing to become a human guinea pig and try it outside the Country?

Edited by OhFuckMyDickHurts

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moialbalushi

But they still need lots of time.  I mean they even didnt start the trials yet. No ? 

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OFMDH
10 minutes ago, moialbalushi said:

But they still need lots of time.  I mean they even didnt start the trials yet. No ? 

They're going to test in monkeys next. People are far off right now.  However the technology and methods are not that new and are applicable as well to HSV1 and HSV2, it could "simply" be adapted to that disease and made in a lab.

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moialbalushi
8 minutes ago, OhFuckMyDickHurts said:

They're going to test in monkeys next. People are far off right now.  However the technology and methods are not that new and are applicable as well to HSV1 and HSV2, it could "simply" be adapted to that disease and made in a lab.

I see. So that is probably 10 years till then it gets approved LoL. Hope the pharmacy's industry doesnt step on the way of it.

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moialbalushi

The monkeys trials will be for herpes or for the technology in general ? 

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OFMDH
3 minutes ago, moialbalushi said:

The monkeys trials will be for herpes or for the technology in general ? 

For HIV, but it could be altered to go after HSV1/2

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Second_chance

@OhFuckMyDickHurts I voted, but can you explain what the survey will be used for? Are you leaving the website due to you working on something regarding HSV

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MoniqueLow
2 hours ago, OhFuckMyDickHurts said:

Please vote. I'm taking off for the summer and maybe longer. Accordingly once this gets past 100 I'll have my answer and will probably be deactivating my account and saying goodbye you'll. 

 

 

We'll miss you.

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useless

I have voted, very sad to hear you are leaving. All your post were interesting and informative.enjoy your summer and I hope you decide to come back to the forum. Good luck.

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Seeker1960
10 hours ago, OhFuckMyDickHurts said:

Please vote. I'm taking off for the summer and maybe longer. Accordingly once this gets past 100 I'll have my answer and will probably be deactivating my account and saying goodbye you'll. 

 

 

Wow, this is a shock. I am going to miss you. Your scientific view point are a great counter balance here. Take care Dark Knight.

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moialbalushi
6 hours ago, OhFuckMyDickHurts said:

I don't want to influence the voting. We need at least 100 people to vote.  Maybe to convince people that we want a sterilizing cure,  gauge people's interest in it, find those who may want to participate one day in a human trial, lobby people in academia, pharmaceutical companies about  incremental improvements are of no interest, to NIH to spend and research more on gene therapy, a NIH grant request....

Leaving is contingent on voting results and voting quantity. I do want to do something this summer and if something were to happen the order would need to be put in soon. BTW I messaged HC support, I don't know if deactivating/deleting my account deletes all my prior posts, some of which I want to save and read later, in the meantime I may just leave it as is.

 

Now you are being a hero man

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Untouchable1
12 hours ago, OhFuckMyDickHurts said:

Please vote. I'm taking off for the summer and maybe longer. Accordingly once this gets past 100 I'll have my answer and will probably be deactivating my account and saying goodbye you'll. 

 

 

Well that's bummer OFMDH and this forum will suffer a huge loss without your input and vast knowledge. Hopefully you can still pop in every now and then. Wishing you the best. 

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SnowAngel

Hey OFMDHs I appreciate you're honesty on here, you will be missed by many. I think I remember you saying that Valtrex is a God sent to you. Can I ask why HSV is such a big deal to you if Valtrex helps stop your OBs? I'm on daily Valtrex but still get OBs and burning pain. 

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Whyyyyy
12 minutes ago, SnowAngel said:

Hey OFMDHs I appreciate you're honesty on here, you will be missed by many. I think I remember you saying that Valtrex is a God sent to you. Can I ask why HSV is such a big deal to you if Valtrex helps stop your OBs? I'm on daily Valtrex but still get OBs and burning pain. 

I know you didn't ask me, Snow...sorry to hijack your comment! But I don't really have outbreaks at all and HSV is still a huge deal to me mentally & I also hate the risk of passing it to someone else :( 

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SnowAngel
26 minutes ago, Whyyyyy said:

I know you didn't ask me, Snow...sorry to hijack your comment! But I don't really have outbreaks at all and HSV is still a huge deal to me mentally & I also hate the risk of passing it to someone else :( 

It's ok! I love hearing opinions. I can completely see what you're saying about not wanting to pass it on, that makes a lot of sense. I hope good things will be coming to help all of us! 

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valleynovascotia

I would do it if they could cure my hpv as well, I hate hearing about poor animals being tested on they can just use me to test on everything.

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valleynovascotia

I voted I feel bad though for all the animals being used is this the only way to find a cure and it seems like a lot of these studies are just pointless cause they fail in the end.

 

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OFMDH
2 hours ago, SnowAngel said:

Hey OFMDHs I appreciate you're honesty on here, you will be missed by many. I think I remember you saying that Valtrex is a God sent to you. Can I ask why HSV is such a big deal to you if Valtrex helps stop your OBs? I'm on daily Valtrex but still get OBs and burning pain. 

Valtrex helps but it doesn't end it. I still get itching and breakout OBs which appear to be about every 2-3 months now. Obviously it still effects my personal life and my health even with Valtrex

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Evaluate

This is quite intriguing to me.  I was curious if someone, with scientific knowledge, would be willing to take on a CRISPR project.

CRISPR kits are available for purchase at a relatively inexpensive price.  The trick is knowing what has already been done, what's failed, what's succeeded, and the hurdles that remain for the technology.  It seems you have a grasp on the field so this should serve you well.

Feel free to ignore this question, as I know you're not wanting to let the cat out of the bag per se, but what makes you confident you can achieve results that academia and biotech start-ups haven't been able to?

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