Jump to content
World's Largest Herpes Support Group

Recommended Posts

GlitterDx

Herpes Article 

Harvey Friedman, a professor of medicine at the University of Pennsylvania. A

"But herpes is a crafty adversary. "The virus contains evasion molecules that allow it to escape your immune system's antibodies," Friedman explains. "That's why we've developed a two-pronged strategy." Along with encouraging your immune system to create those cell entry-blocking antibodies, Friedman's vaccine also prevents the herpes virus from putting on a disguise that hides it from your immune system. "

https://tonic.vice.com/en_us/article/why-we-dont-have-a-herpes-vaccine-yet?utm_source=tonictwitterus

Edited by GlitterDx

Share this post


Link to post
Share on other sites
GlitterDx

The new “trivalent” vaccine induces antibodies against three different parts of the virus, including two components that normally help HSV2 evade immune attack.

 

More scientific explanation 

https://www.pennmedicine.org/news/news-releases/2017/january/new-genital-herpes-vaccine-candidate-provides-powerful-protection-in-preclinical-tests

 

Share this post


Link to post
Share on other sites
Lauren401

"Of course, there are other researchers working on herpes vaccines—as well as treatments. But none are farther along the road to approval and adoption than Friedman's. So while there's hope, the hopeful will have to sit tight a while longer."

 

Is this actually true? (from the first link sent) @GlitterDx

Share this post


Link to post
Share on other sites
GlitterDx

Who knows. They are all tooting their own horn. But the more the merrier until then.

"Trivalent" sounds good tho. ;)

Edited by GlitterDx

Share this post


Link to post
Share on other sites
howardsmith8888

@GlitterDx Thank you for sharing these articles.  However, please be advised that they were not recently posted - the second being from January.

Share this post


Link to post
Share on other sites
OffTheGrid
On 6/5/2017 at 4:21 PM, GlitterDx said:

Who knows. They are all tooting their own horn. But the more the merrier until then.

"Trivalent" sounds good tho. ;)

They might just find the perfect combination with all these scientists testing it from multiple directions. Hopefully they could collaberate then expedite one by tweaking the formula already moving through the trial process. Herpes multi-unit think tank / laboratory financed by entrepreneurs!

Share this post


Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.


  • Similar Content

    • TerribleAtUserNames
      By TerribleAtUserNames
      Hi there, 
      Long time lurker, first time poster, and I'll keep it simple and condensed. 
      I've only signed up because I realize the depths of suffering some people are in, trying all sorts of desperate treatments, and I've basically been sitting on something that has taken me to near 0 outbreaks (hsv1 genital).
      When I first got infected some years back, I had an atypical presentation--no pain or itching, but permanently there. Bumps going up and down within the same day even, but pretty much permanently covering the head of my penis. Doctor swabbed it--came back hsv 1; he said it looked like it to him too. 
      Now to the meat of it--rubbing alcohol.
      Its simple, and I'm pretty surprised that I've only seen it mentioned once here--a woman was talking about it, so I assume it works for girls too. I apply once daily, to once every 3 days, and that keeps me pretty much permanently outbreak free. 
      It quite literally went from every day broken out for me to just about nothing. Anyway, to the what and where of it all... 
       
      I use 99% isopropyl. 70% seems good too. I now have a spray bottle, but used to just dump it on the head and roll my foreskin up over it for like 20ish seconds--whatever process is actually happening, I like to think I'm facilitating absorption into the soft tissue by doing this and wreaking havoc on the virus. Obviously, you may have to do it a bit differently, genital depending.
      I've been doing this treatment for a few years now, so it has staying power. I read once that herpes is shreded by alcohol, so if true, I guess that explains it? However, iterupting regular treatment seems to have anecdotally, but not with great surety, made the herpes a bit less suceptible to the alcohol upon resumption. 
      Yes, it burns terribly at first. Over time it gets better. Some days it still really burns, and in those cases I advise listening to your body and cutting the countdown short. Other than that, it feels really damn good to basically tell herpes to eff off. 
      I don't know what kind of health risks there are. Or whether using a high % grain (drinking) alcohol would work / be healthier. I advise asking your doctor--afterall, alchohol is implicated in throat cancer. Who knows if 20-30 seconds daily on your junk can do something too. 
      But for those who struggle constantly, I truly hope this can help someone other than just me. 
       
      I also hope that this finds its way to the right forum. I wanted it in a place where casual, straight from Google, viewers would see it when they came here, and I'm hoping--and asking, please--that if I didn't get it in the right place, a moderator can instead. And, should it help as I suggest, perhaps even stickying it one day. 
      I'm sorry in advance, I'm not a big forum person and don't come here crazy often. It just felt like something I should do for everyone else's sake. Hopefully you can excuse me if I'm an absentee topic starter. 
      Thanks for reading,
      - Taylor
    • ManagingIllness
      By ManagingIllness
      Full paper here: https://www.sciencedirect.com/science/article/pii/S0264410X18315652
      Note sure if anyone wrote about this. I couldn't find any results for VC2 in the site's search. This is a live attenuated vaccine from Louisiana State University. The results do not seem super promising, as reducing shedding/recurrance by < 70% pre-clinical is common in many discontinued vaccines. Still, research is being done, which is always great!
      Prophylactic conclusions:
      "Our studies also showed that VC2 vaccine decreases the clinical severity of acute and recurrent HSV-2 disease in guinea pigs when provided by intramuscular vaccination. During the primary infection, animals vaccinated with VC2 had a significant decrease in clinical severity and replicating virus in the vaginal vault. Prophylactic vaccination also decreased the quantity of virus in the DRGs when compared to the No Treatment group. The ability to protect neural tissue from latent infection probably contributed to the decrease in the number of animals with recurrent lesions by 67% and the number of days with recurrent vaginal shedding by 46%. This reduction in shedding is particularly important because transmission of HSV-2 to uninfected persons is largely due to asymptomatic shedding [38], [39]."
      Theraputic conclusions:
      "When tested as a therapeutic vaccine, i.e., one designed to decrease recurrent disease and recurrent virus shedding in those already infected with HSV, the VC2 vaccine was not effective although it did reduce recurrent shedding, at least when compared to the gD2 vaccine. This may be because live attenuated vaccines have only limited replication in hosts that are already infected and thus do not have much of an impact in improving the immune response. Because infected hosts have frequent reactivations of virus that would be similar to a live vaccine inoculation it may be difficult for the vaccine to improve the immune response unless it is able to induce responses not activated by the host’s recurrent virus replication."
    • Editas83
      By Editas83
      I'm sure a lot of you Google "hsv2-cure" daily like me. Looks like there may be a twinkle of hope. Not a cure, but at least some new news.
      https://www.precisionvaccinations.com/gen-003-therapeutic-bivalent-vaccine-candidate-genital-herpes-simplex-virus-type-2-hsv-2
       
       
    • Jimmyjimmyhuapua
      By Jimmyjimmyhuapua
      Found a good article what do you think ?
      https://www.smithsonianmag.com/science-nature/can-we-gene-edit-herpes-away-180968551/
    • GlitterDx
      By GlitterDx
      The new "trivalent" vaccine induces antibodies against three different parts of the virus, including two components that normally help HSV2 evade immune attack.
      "It's a novel strategy, and it works beautifully," said senior investigator Harvey M. Friedman, MD, a professor of Infectious Diseases at Penn. "I know of no other HSV2 vaccine candidate with published results that are as promising as this study."
       
      https://www.sciencedaily.com/releases/2017/01/170119163444.htm
       
  • Trending Now

  • The Hive is Thriving!

    • Total Topics
      69,761
    • Total Posts
      470,435
  • Posts

    • TerribleAtUserNames
      Hi there,  Long time lurker, first time poster, and I'll keep it simple and condensed.  I've only signed up because I realize the depths of suffering some people are in, trying all sorts of desperate treatments, and I've basically been sitting on something that has taken me to near 0 outbreaks (hsv1 genital). When I first got infected some years back, I had an atypical presentation--no pain or itching, but permanently there. Bumps going up and down within the same day even, but pretty much permanently covering the head of my penis. Doctor swabbed it--came back hsv 1; he said it looked like it to him too.  Now to the meat of it--rubbing alcohol. Its simple, and I'm pretty surprised that I've only seen it mentioned once here--a woman was talking about it, so I assume it works for girls too. I apply once daily, to once every 3 days, and that keeps me pretty much permanently outbreak free.  It quite literally went from every day broken out for me to just about nothing. Anyway, to the what and where of it all...    I use 99% isopropyl. 70% seems good too. I now have a spray bottle, but used to just dump it on the head and roll my foreskin up over it for like 20ish seconds--whatever process is actually happening, I like to think I'm facilitating absorption into the soft tissue by doing this and wreaking havoc on the virus. Obviously, you may have to do it a bit differently, genital depending. I've been doing this treatment for a few years now, so it has staying power. I read once that herpes is shreded by alcohol, so if true, I guess that explains it? However, iterupting regular treatment seems to have anecdotally, but not with great surety, made the herpes a bit less suceptible to the alcohol upon resumption.  Yes, it burns terribly at first. Over time it gets better. Some days it still really burns, and in those cases I advise listening to your body and cutting the countdown short. Other than that, it feels really damn good to basically tell herpes to eff off.  I don't know what kind of health risks there are. Or whether using a high % grain (drinking) alcohol would work / be healthier. I advise asking your doctor--afterall, alchohol is implicated in throat cancer. Who knows if 20-30 seconds daily on your junk can do something too.  But for those who struggle constantly, I truly hope this can help someone other than just me.    I also hope that this finds its way to the right forum. I wanted it in a place where casual, straight from Google, viewers would see it when they came here, and I'm hoping--and asking, please--that if I didn't get it in the right place, a moderator can instead. And, should it help as I suggest, perhaps even stickying it one day.  I'm sorry in advance, I'm not a big forum person and don't come here crazy often. It just felt like something I should do for everyone else's sake. Hopefully you can excuse me if I'm an absentee topic starter.  Thanks for reading, - Taylor
    • WilsoInAus
      Hey @Jazz923 they don’t look like herpes lesions, more like pearly papules that some guys get.  I’d suggest these are independent of your herpes status. The question of your herpes status will depend on the test that you had. What test suggested you had HSV-2? Was it a blood test?
    • Jazz923
      I recently seen these bumps on my penis didn’t hurt or itch only broke because I was masturbating (dumb move) this cleared up in week I got test and said it was hsv 2 but my gf got tested and had nothing I didn’t experience the things I seen on google and I didn’t take the medicine cause it has the virus in it I just need a bit more clarification like any kind of test or anything helps     https://ibb.co/pRm0VbJ
    • Sarah889
      So I guess I'm just on here for a bit of a rant, as today I woke up with my second outbreak in a month! My initial one was only at the end of April, and even after investing in a load of vitamins, lysine etc I'm in this situation again. I was hoping I'd be one of those who never gets another outbreak, but apparently not.  I think the problem is, I really liked my life before all of this crap, and I don't really want to have to change anything. Going to the gym is amazing for my mental health, and i normally go around 4 times a week. I also love a bit of chocolate every day (but I eat super healthy for the majority of the day) and being a uni student, I'm partial to a few cocktails and late nights every month as well. This is my time to socialise with my friends and have some fun. At 21 you really don't want to be taking your life too seriously.  Does anyone else just feel annoyed about having to switch up a happy life that they enjoy? I understand there's a lot of people who had unhealthy lifestyles before their diagnosis, that went on to lose weight which is great! But I'm already slim and active, and I eat freshly cooked food every day with lots of fruit and veggies.  I'm starting to believe that the only way to avoid an outbreak is to sit in my flat eating salads all day and have no contact with anyone else (in case of stress). Like I legit feel like I need to wrap myself up in cotton wool and just not allow myself to have a life at all. I'm so frustrated that I have to stop doing the things that I love. I'm going travelling next month, and I would bet all the money that I have that I will get another outbreak, because of the plane journey, late nights and alcohol. I just want to be a normal 21 year old who gets to enjoy her life! Does anyone else feel the same? 
    • BioHacker
      The meds work the same as long as you take them every day (some are one a day, some are multiple times per day). They cost money, but there is no reason you can't take them for life. Most people would just take the meds, but if you are married for 20 years and the meds are annoying for some reason, and you don't care about it, then maybe don't bother? It's up to the two of you. Skipping the daily meds would increase the risk from 0.7% per year to 1.4% per year (assuming sex 2x per week). That changes it from a 1-in-140 year event to a 1-in-70 year event (assuming you still use condoms every time). To be honest, most married people would probably rather skip the condoms before they skip the meds. It's up to you what measures you take though.
×
×
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.