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I love every interaction that I have with another human being. Some are hostile (my least favorite), but others (most often, for me), are tolerant. I have a full time job that pay well, but I recently started sharing rides. I've had one person in the car that just got his PhD in HSV-1 research focused on autophagy. He was in David Knipes lab, now he's on his own (lol). He's a post-doc trying to further his career, and he's looking for prospects like the rest of us outside of this place. He described the autophagy process for hsv. His thesis was based in the idea that herpes simplex can avoid the cell's ability to activate defenses after and before infection. It was a really, really interesting discussion. What I gathered from that conversation, and without disclosing or controlling the direction, was that he loved his field but that he saw little willigness to pursue the issue. His wife, also a PHD student at Harvard (graduates this year) is working on HIV. This, despite what's already been done, is what people care about now. The drugs available are good - really good. But they continue to concentrate there because of the immediate stigma and potential for death. HSV will kill not a single one of us. The puzzle for scientists that makes it interesting is in how it lays dormant. Convincing the scientific (not the medical), community to pay attention has more to do with scientific aqvuienece than anything else.

interesting conversarion to be sure. Important to remember, though, is that the cure matters zero to scientists. Pharmaceutical companies are key in this respect. Development is expensive and so incredibly unsure. Micah and Cracker, spread the word, Keep doing what you're doing. But do it better. It's hard to wave down pharma companies, but awareness does work. Trust me: every time I see a patient that comes in and presents their illness, it crushes me, heart and soul.

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Does that mean autophagy does not help with HSV? I've been looking into inducing "Chaperone-mediated autophagy" via starvation as a potential remedy for herpes - if you run into your carpool partner again, can you check with him if there is any form of autophagy that can help with herpes? 

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