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Phoenixx

Valtrex side effects - do they vanish?

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Valtrex is giving me headache and nausea. I can only take max. 250mg at a time, otherwise the side effects are too strong and I can't work anymore. I take it after meals and lack of drinking is definitely not the reason.

What is your experience? Do the side effects vanish after some time? I don't know how I'm supposed to hang on like this. Acyclovir is not an alternative because it causes diarrhea. I think that headache and nausea are also side effects of Acyclovir, but I didn't notice them that much because it's only absorbed to 10-20% in the guts, so the main effect (80-90%) of Acyclovir is the side effect happening in the gut.

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even i'm having headaches after try anti virals, and it is persisting even after stopping it. IDK what to do ! what is causing my headaches.

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I tend to have trouble when I first start taking it for around a week or two. It helps me to drink a lot more water than is typical for me. I have an entire glass or two with the pill for starters.

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yeah, I felt like ass on Acyclovir so I don't take it.  It goes away when you stop taking it.

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I'm on suppressive valacyclovir. I had some headache at first whenever I reached 1 gr/day to stop an OB, but after a month or so it went away. Now I can take 2 gr/day when necessary. I guess you build tolerance with time.

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On 12.10.2017 at 10:34 PM, friendlyboy said:

I'm on suppressive valacyclovir. I had some headache at first whenever I reached 1 gr/day to stop an OB, but after a month or so it went away. Now I can take 2 gr/day when necessary. I guess you build tolerance with time.

Then that is my only remaining hope for now...

My last hope for an available drug without side effects was just destroyed. Yesterday night before sleeping I tried 125mg of Famvir (Famciclovir) because the chemical structure of Penciclovir is slightly different from Acyclovir and I was hoping for a noticable difference. Even though it was the lowest dosing I woke up with strong headache and mild nausea - exactly the same side effects as Valacyclovir.

I guess I have to try slowly increasing Valacyclovir then because it's cheaper than Famvir. You are lucky that your headache on Valacyclovir starts at 1g/day. It's ridiculous, I'm already breaking the 500mg pill in half and then biting off half of that half because I can't break it manually anymore. Even these 125mg still give me mild headache.

There is no other option anymore because Acyclovir is provoking watery diarrhea and that ends up in a vicious circle: diarrhea weakens the immune system and provokes herpes outbreaks.

What a pity that Brivudine is not effective against HSV-2. That would have been another option, especially because it's chemical structure is quite different from Acyclovir and Penciclovir, making it likely to not cause the same side effects.

Edited by Phoenixx

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