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Southwestrancher

NanoViricides

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dont quit!17

Interesting to see how this plays out. Vaccines seem to be mostly ineffective for HSV. Maybe an odd combo of Valtrex and Nanoviricides is the answer? Thanks for the share. 

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Southwestrancher
7 minutes ago, dont quit!17 said:

Interesting to see how this plays out. Vaccines seem to be mostly ineffective for HSV. Maybe an odd combo of Valtrex and Nanoviricides is the answer? Thanks for the share. 

 I agree. Vaccines of 99% even don't cut it. From what I've read they cure it. Cautiously optimistic. ❤️❤️

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cowpoke02

nano is bad for people ..  i invest in this stock day trades . haha..  maybe in medicines  . nano usually involves metals lodged into the body ..  like from chemtrails to other vaccines .  oh well .  if they find half safe deal sounds good .  cheap stock to .  money maker.  won 16 bucks on it today . 

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Southwestrancher
On 3/24/2018 at 8:00 PM, mcmich said:

NanoViricides has been in testing for at least 10 years with little progress. Don't want to dampen your spirits but they have been working on this for 10 years and have not progressed beyond animal studies in all that time.At their current pace of research, 20 years min before they get anything to market.

Nanobio had a similar product 11 years ago that made it through Phase 2 testing and had a agreement with GSK to license it as the next generation Abreeva (since it was going off patent) and it quietly died.Made it into Phase 3 but never saw any published results. Supposedly was highly effective and some of the members here were part of the trial at the time.

https://www.businesswire.com/news/home/20110511005464/en/NanoBio-GSK-Commence-Phase-3-Studies-Nanoemulsion-based

https://clinicaltrials.gov/ct2/show/NCT01695187

Two different companies. NanoViricides has had some pretty promising results recently. I'm optimistic. 

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PeaceNeeded

Read interesting things from http://www.vical.com and  genocea.com

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Southwestrancher
1 hour ago, PeaceNeeded said:

Read interesting things from http://www.vical.com and  genocea.com

Anything 95, 96, 98, 99% is no good to me to tell you the truth. I want it out of my body, completely. Or so I can't give it to anyone else. That's really all that matters to me.

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PeaceNeeded
17 hours ago, Southwestrancher said:

Anything 95, 96, 98, 99% is no good to me to tell you the truth. I want it out of my body, completely. Or so I can't give it to anyone else. That's really all that matters to me.

well of course, I hope that we reach that kind of cure sooner or later.

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brookeb300

I wish this stuff would come out or move along into clinical trials what is taking so long?

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Southwestrancher
18 minutes ago, brookeb300 said:

I wish this stuff would come out or move along into clinical trials what is taking so long?

All this stuff takes soooooo long. I need it today. 

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Divon
On 5/23/2018 at 3:51 AM, Southwestrancher said:

Anything 95, 96, 98, 99% is no good to me to tell you the truth. I want it out of my body, completely. Or so I can't give it to anyone else. That's really all that matters to me.

Alright slow down mr needy. You do realize that if we can suppress it that much it will be almost irrelevant that you give someone HSV right? You probably have other herpes viruses in your body too like VZV (chicken pox), Im assuming you dont demand to have them removed from your body do you?

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Southwestrancher
11 hours ago, Divon said:

Alright slow down mr needy. You do realize that if we can suppress it that much it will be almost irrelevant that you give someone HSV right? You probably have other herpes viruses in your body too like VZV (chicken pox), Im assuming you dont demand to have them removed from your body do you?

"irrelevant that you give someone HSV"?  ......Ok....see ya.

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Divon
On 7/30/2018 at 5:17 PM, Southwestrancher said:

"irrelevant that you give someone HSV"?  ......Ok....see ya.

Maybe not entirely ofc since they would still have to go through the job and cost of taking the treatment. Assuming they would even have it active enough to even want to bother getting it treated.

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Divon

On the topic though, I really think or more or less can guarantee that nano technology is the answer to the viruses in the world. However I would be refering to nano sized robots then that enter the body to target a virus. As far as I know this is technology for 2040 or so though. Nano nano nano.. it has been the science dream for many years.

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Southwestrancher

Nanoviricides Inc. to Present at 20th Annual Rodman & Renshaw Conference in NYC on Sept 6th

SHELTON, CONNECTICUT -- Wednesday, September 5, 2018 -- NanoViricides, Inc. (NYSE MKT: NNVC) (the "Company") a global leader in developing nanomedicines to attack viruses, announced today that it will be presenting at the 20th Annual Rodman & Renshaw Global Investment Conference, sponsored by H.C. Wainwright & Co., LLC. The conference is being held on September 4-6, 2018 at the St. Regis New York Hotel in New York City.

Dr. Anil Diwan, President and Chairman of the Board of NanoViricides, will present a corporate overview and discuss the Company's progress in taking its first drug candidate into human clinical trials. He will also introduce the Company's new CEO, Dr. Irach Taraporewala. The presentation is scheduled for 3:25pm ET on Thursday, September 6th, 2018.

The Company has updated its corporate "fact sheet", or brochure, and it is available on the Company's website at www.nanoviricides.com.

The Company has a broad and deep pipeline of drug candidates based on its unique, post-immunotherapeutic "bind-encapsulate-destroy" "nanoviricide®" technology platform, that addresses a market space of $40 Billion to $70 Billion. The Company is currently focused on developing topical skin creams and eye drops in the HerpeCide™ program to treat infections caused by VZV, HSV-1, and HSV-2 herpesviruses, towards regulatory approvals. These drug candidates leverage significant amounts of common technologies, thereby enabling the Company to maximize return on investments (ROI).

The Company has previously reported that its lead anti-VZV drug candidates in the HerpeCide™ program have been found to be highly effective against VZV infection of human skin patch organ culture studies. These candidates were also found to be highly effective in cell culture studies. In addition, these candidates were found to be effective in ameliorating pain sensations in an animal model of abnormal (neuropathic) pain. A characteristic excruciating pain is a debilitating pathology of shingles presentation. Thus a direct pain-reducing effect of the Company's anti-shingles drug candidates would be very important in ameliorating the pathology of shingles, in addition to the already demonstrated significant antiviral effect.

There are currently no approved treatments for shingles, PHN, or chickenpox, representing a commercially valuable unmet medical need. All of these are diseases caused by VZV. A highly effective treatment of shingles that would result in reduction in the duration and severity of PHN cases has been estimated to have a potential market size in the range of billions of dollars, even after the recent introduction of the new Shingrix vaccine. There are approximately 500,000 to 1 Million episodes of shingles hospitalization cases annually in the United States alone. Approximately 18% of patients overall, and as many as 30-50% of older patients with shingles, are estimated to have PHN. This represents more than 200,000 cases of PHN annually in the USA alone. Such VZV complications can cause extended hospitalization in about 4% of shingles patients overall, with an average estimated cost as high as $20,000 per hospitalized patient.

The Company has also found that these candidates were extremely safe in a preliminary rat safety/toxicology study. This has led to a redesign of the IND-enabling Safety/Toxicology study ("Tox Package") to be performed at the "maximum feasible dose" (MFD) level. This is estimated to require multi-kilogram quantities of the drug candidates. The Company has recently started production of the necessary quantities of the drug candidate at our cGMP-capable facility in Shelton, CT. The Company expects to begin "Tox Package" studies once the drug is manufactured in the multi-kg quantities needed and is already in negotiation with a CRO site for the study. The acute dermal safety/tox study is expected to be of a relatively short duration and we anticipate filing an IND once the report is available.

All of our drug candidates are based on broad and exclusive licenses in perpetuity from TheraCour Pharma, Inc. A license for VZV and the remaining herpesviruses is in progress. HSV-1 and HSV-2 are already licensed, as well as many other viruses including all influenzas, HIV, Dengue, Ebola/Marburg, among others. For further details, please refer to our quarterly and annual reports.

Shingles is caused by reactivation of the Varicella Zoster Virus (VZV, aka human herpesvirus-3 or HHV-3). A chickenpox (i.e. varicella) infection in childhood leads to the virus becoming latent in the nervous system. At an older age, or when immunity against this resident latent virus decreases, the virus replicates in the nerve cells, and bursts out of the nerve endings infecting neighboring skin cells, thus causing a typical shingles rash. The nerve injury caused by the virus leads to a characteristic excruciating and debilitating pain. The shingles rash may continue to expand for several days, and then subsides in about three weeks in an uncomplicated case. The VZV-associated neuropathic pain does not resolve quickly, and may continue even after the rash has resolved (hence called PHN), for several months to, in rare cases, years.

About NanoViricides 
NanoViricides, Inc. (www.nanoviricides.com) is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. The Company is developing drugs against a number of viral diseases including H1N1 swine flu, H5N1 bird flu, seasonal Influenza, HIV, oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis, Hepatitis C, Rabies, Dengue fever, and Ebola virus, among others. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actual events could differ materially and substantially from those projected herein and depend on a number of factors. Certain statements in this release, and other written or oral statements made by NanoViricides, Inc. are "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors which are, in some cases, beyond the Company's control and which could, and likely will, materially affect actual results, levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, even if new information becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include, but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities.  Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful commercialization of our product candidates; and market acceptance of our products.

FDA refers to US Food and Drug Administration. EMA refers to the European Union’s office of European Medical Agency.


Contact: 
NanoViricides, Inc.
Anil R. Diwan

Edited by Southwestrancher

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Quest

I hope they put something on YouTube that would be really neat from the conference!

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Little Star

I personally don’t have much hope in some eye drops and a topical cream plus the website looks like shite but thanks for posting :joy:

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mcmich

This is a topical solution you use after you break out. Will not cure you since it does not get to the ganglia and kill the infected nerve cells (probably do not want to do that anyway).

I was infected 10 years ago and found this company back then. Basically has not made any movement from the pre clinical phase in all that time. While it may be a better Abreeva,

it just treats the symptoms to lessen them and shorten the duration (from what I read). At the pace they are moving it will be 10-20 years from now. Probably have a CRISPR cure before then.

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Southwestrancher
On 10/15/2018 at 11:18 PM, mcmich said:

This is a topical solution you use after you break out. Will not cure you since it does not get to the ganglia and kill the infected nerve cells (probably do not want to do that anyway).

I was infected 10 years ago and found this company back then. Basically has not made any movement from the pre clinical phase in all that time. While it may be a better Abreeva,

it just treats the symptoms to lessen them and shorten the duration (from what I read). At the pace they are moving it will be 10-20 years from now. Probably have a CRISPR cure before then.

Totally wrong. 

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Southwestrancher
On 10/15/2018 at 1:49 PM, Little Star said:

I personally don’t have much hope in some eye drops and a topical cream plus the website looks like shite but thanks for posting :joy:

You should have read about some of the things they're working on. It's not about some "eye drops and a topical cream".  What a moron  you are "little" star.

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