Jump to content
World's Largest Herpes Support Group
Sign in to follow this  

Drug repurposing: omeprazole increases the efficacy of acyclovir against herpes simplex virus type 1 and 2

Recommended Posts


Check out this article on repurposing Omeprazole (PRILOSEC).  Taken with Acyclovir it increases the efficacy of acyclovir. Note all this was done in Vero (petri dish).  But since Prilosec is well tolerated in most it may be something to look into to see if it can help control outbreaks. Both medications would need to be taken at the same time, Prilosec and Acyclovir or Valacyclovir.  I'm getting some Prilosec today!  


Edited by TCBH
wrong info

Share this post

Link to post
Share on other sites

Omeprazole half-life is 1-1.2 h, while acyclovir half-life is 3 h, you would need to take it much more often.

Furthermore, there are risks associated with long term consumption.

But it is interesting for short term usage like when you are having an OB.

If you are on suppressive AV treatment, when having an OB you could try omeprazole instead of ramping up the acyclovir dose.


Share this post

Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
Sign in to follow this  

  • The Hive is Thriving!

    • Total Topics
    • Total Posts
  • Posts

    • Evaluate
      If your eye was affected by HSV you'd be in intense pain and you'd be in the hospital on an antiviral drip.  It is likely a coincidence of timing, and something that you shouldn't overthink.  Definitely worth getting checked anyway since the eye is a sensitive area.
    • information seeker
      I been taking meds, but has not gotten better. I will crop a picture to show you in a few hours. I seeing the top doctor in Tokyo this month
    • woodrose
      I found this website today. You can now pre order Viblok but no potential delivery date is given. The company is in Florida and I called but got a recorded message. https://www.viblok.com/
    • woodrose
      Here's something interesting. You can now pre-order Viblok.  However, the website does not indicate when it will be available. https://www.viblok.com/
    • JD2424
      Hey all. I had an STD check while pregnant with my now 3 yo and it was perfectly clean, hadn’t had another one until a few months ago   I was sexually assulted about 4 months ago. Because of that I asked for all STD testing. My first HSV 2 IGG score came back at 4.00, I requested another 2 weeks later and it’s now a 3.22 IGG. Should I take this as for sure positive or would it warrant a WB at all? Is it normal for numbers to go down like that?   Ive had NO symptoms whatsoever, at any time     Also, condoms, guys what are the best ones that feel as natural as possible?? Any ideas? 

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.