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Drug repurposing: omeprazole increases the efficacy of acyclovir against herpes simplex virus type 1 and 2

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Posted (edited)

Check out this article on repurposing Omeprazole (PRILOSEC).  Taken with Acyclovir it increases the efficacy of acyclovir. Note all this was done in Vero (petri dish).  But since Prilosec is well tolerated in most it may be something to look into to see if it can help control outbreaks. Both medications would need to be taken at the same time, Prilosec and Acyclovir or Valacyclovir.  I'm getting some Prilosec today!  


Edited by TCBH
wrong info

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Omeprazole half-life is 1-1.2 h, while acyclovir half-life is 3 h, you would need to take it much more often.

Furthermore, there are risks associated with long term consumption.

But it is interesting for short term usage like when you are having an OB.

If you are on suppressive AV treatment, when having an OB you could try omeprazole instead of ramping up the acyclovir dose.


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Try a Lysine supplement for cold sores

  • The Hive is Thriving!

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    • Dutchy
      Hi! I was diagnosed one year and four months ago. Not a major first outbreak. Than 2,5 months later my second. Then faster a Little ob. Then is was without for almost 7 months. I really felt that was how i could handle things. Then in June i started having ob after ob. It was a very hot summer here in Holland. Also started a new relationship so more frequent sexual Activity. Not sure what coused it but those things i did feel like could trigger it.  Started acyclivir two months ago. That helps a great deal. But really dont want to Stay on Anti virals. Willing to try natural stuff but also right now feeling very happy not worrying all the time. Need to discuss again with my doctor soon.  
    • LovelyVirgo
      I had an igg test done I believe. I was diagnosed with hsv2 genital 
    • LovelyVirgo
      Oh wow that sounds mind boggling,, maybe your diet is your problem as well. Dang I thought guys had it a little easier seeing as tho you could keep your ob's dry better than a woman for it to heal..  I've never heard of Neem what's is that
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      Yea I believe it may have to do with my diet i just recently cut out beef, chocolate & nuts & started eating more fish & fruits & smoothies and my symtoms are going away suprisingly. I think it was more so the chocolate for me lol smh im gonna miss it. And NO WAY your stomach!?? Like how does that happen lol that's so weird
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      No, nothing looks like herpes.

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