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Lymph nodes in recurring outbreaks

Hopefulmi

By Hopefulmi,
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Hopefulmi Honeycomb Member

Hopefulmi

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Posted

Hi

i was diagnosed 2 years ago with HSV-1 (genital). The initial outbreak was horrific and since then I’ve have a few mini outbreaks. Currently going through a big one, the worst since my first and my lymph nodes in groin are swollen again. Is this normal? You mostly read about it happening just the first time.

 

thanks in advance

 

Naomi 

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  • 4 weeks later...
Feeling Normal Again Established Member

Feeling Normal Again

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I had swelled and painful groin and ab lymphnodes. It was almost crippling!

 

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Terrell Platinum Support Member

Terrell

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Interesting because the immune system should be aware of the virus and have sufficient b, t, and memory cells on deck to prevent such a horrific outbreak lymphocytes is the filtering process 

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Feeling Normal Again Established Member

Feeling Normal Again

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On 6/2/2018 at 10:42 PM, Terrell said:

Interesting because the immune system should be aware of the virus and have sufficient b, t, and memory cells on deck to prevent such a horrific outbreak lymphocytes is the filtering process 

Sorry this is so long!

From what I've read,  because the virus goes into latency, the t cells (memory cells) cannot always perform as proficiently as they should. And then depending on the individual's virus--how quick and far the virus travels through the CNS--determines severity and frequency of symptoms and outbreaks.

This is why some people are exposed and never have an outbreak. Other individuals are exposed, have one initial outbreak, and then never have another one. And some people have three to five a year; others get constant outbreaks. 

For genital hsv, the body's closest line of defense is the groin lymphnodes (production of b cells). In some people, this can cause pain. 

I'll try to find the link to this information. It was a journal I read awile back. The main content of journal was the reasons they're having trouble with hsv vaccines in humans, and trials are not successful, but they're are having successful trials in mice. I will also try to find the link for original studies done on mice. Both are definitively interesting reads! 

 

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