Jump to content
World's Largest Herpes Support Group
allhereto

High dose (2grams/day) Valtrex suppressive therapy -long term

Recommended Posts

allhereto

I have constant cold sore outbreaks, and I've tried natural remedies with limited success (olive leaf extract, lysine supplements, zinc, and vit. c). I have also been on a suppressive dose of Valtrex for 6 months now - 500mg twice daily - still having back to back outbreaks. I  recently asked my doctor to let me increase my Valtrex dosage to 1,000mg twice daily for long-term suppression.  Is there any research to support a dosage this high every day/longterm for more effective outbreak control for oral or genital hsv?

Share this post


Link to post
Share on other sites
WilsoInAus

Unfortunately the effect tops out at about 1g per day. Any excess is typically redundant.

What and where are these outbreaks? 

The focus probably needs to be on a form of you being immunocompromised. 

 

Share this post


Link to post
Share on other sites
hellohello111
6 hours ago, allhereto said:

I have constant cold sore outbreaks, and I've tried natural remedies with limited success (olive leaf extract, lysine supplements, zinc, and vit. c). I have also been on a suppressive dose of Valtrex for 6 months now - 500mg twice daily - still having back to back outbreaks. I  recently asked my doctor to let me increase my Valtrex dosage to 1,000mg twice daily for long-term suppression.  Is there any research to support a dosage this high every day/longterm for more effective outbreak control for oral or genital hsv?

Have you asked your doc for Denavir cream? It’s a topical for cold sores and is pretty awesome. You take that coupled with valtrex and you should be good. 

Share this post


Link to post
Share on other sites
hellohello111

Also, let’s dig a bit deeper. What’s your diet like? Exercise? Age? Are you immune compromised? What HSV do you have? How long have you had it? What did you do before valtrex? This will help

Share this post


Link to post
Share on other sites
allhereto

Thanks, guys for the responses! I'm 38 years old, not immune compromised, and I have hsv 1 - cold sores under my nose and all around my lips...usually one blister per outbreak, and I never had outbreaks until about 6 years ago....although I know I was infected prior to that.  I also get genital HSV 1 outbreaks about twice/year. I eat fairly healthy (low carb), I do drink whey protein shakes, but the lysine/arginine ratio seems to be good; I also avoid common trigger foods. I walk about half an hour 4 days/week, and do yoga for about an hour once a week.  My  stress level is really high now due to my job and a recent break up, so I'm sure that is a contributing factor....I've been up to 1 year between outbreaks when my stress level was lower. Before Valtrex, I used Acyclovir 400 mg twice daily for suppressive therapy, and I can't really tell a difference in effectiveness. I did seem to have success with Thorne Olive Leaf extract 500 mg twice per day - helped keep me outbreak free for around a year - without any anti viral medication, but I had a genital outbreak after about a year and stop using it. Lysine at 3 grams per day may helped some, but didn't seem strong enough for me. Abreeva seems to help speed up healing time, but isn't particularly effective. I haven't tried Denavir cream....I may ask for that next. Anyways, thanks for the tips!

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

Advertisement

Try a Lysine supplement for cold sores

  • The Hive is Thriving!

    • Total Topics
      67,406
    • Total Posts
      448,515
  • Posts

    • LWestCoast
    • BPKU
      Ok. That's true. I would def. use protection but i was just thinking I should say something. I haven't made an decisions yet so nothing has happened. And also thanks for your response.
    • Xmk224
      Im thinking alot of one night stands are usually ppl you dont know. So i assume alot of ppl take the risk and have protected sex or even unprotected sex knowing they will never see thst person ever again. Especially if the transmission rate is low while using protection
    • BPKU
      I mean by that same logic anybody would be crazy to have sex with us ever  lol ppl we end up in relationships with are at risk the most aren't they? Since that would mean regular sex...  I'm asking to see if anybody has ACTUALLY disclosed to a one night stand because I've read on other sites that ppl have done it but most are blogs like the one here https://www.emilydepasse.com/eldsoul/2018/3/25/ask-emily-dating-with-herpes where basically the writer is responding to a question vs me actually having the ability to talk to the person who actually has the experience 
    • 2kroc
      http://www.eligiblemagazine.com/2013/03/14/lube-up-with-coconut-oil/ https://www.ncbi.nlm.nih.gov/pubmed/10813049 https://www.drgonzalezmd.com/avoid-secondary-herpes-infections-with-coconut-oil/   Coconut Oil has been shown to contain alot of antiviral properties. Herpes simply cannot survive in it, however I'm curious at how effective it is at preventing herpes transmission during sex, and if it'd make you near invincible. Herpes during sex is transmitted through skin to skin friction which coconut oil significant reduces.  Also if the virus were to leave the carrier's body it would get caught up in the layer of oil and killed. But how fast? Also, The lube drys out as you rub against each other, so you'd have to keep re-applying every so often.   Depending on the intensity of the sex, the coconut oil will get thoroughly rubbed into the persons skin layers, which'd mean the virus undoubtedly be on the persons skin and flesh. But, Theoretically, The virus should be dead/inactive due to being surrounded by the anti viral coconut oil, so it wouldn't even be able to crawl into their body to infect.   We need to get a bunch of lab mice or monkey, Infect 2 with herpes (Control and Test groups) , cover the test group in coconut oil, and let them have sex. If the test group shows less herpes transmission rates than that means that Coconut oil decreases STD TRANSMISSION!   Why hasn't this been done yet? Even if it didn't reduce transmission by 100%, 50% would lower std rates significantly.
×

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.