Moving on. What’s happening with HSV529 vaccine?

[LeftCoast]

When do Phase 2 trials for Sanofi Pasteurs HSV 529 vaccine start? 

[Daisy777]

I have found this link please check:

https://clinicaltrials.gov/ct2/show/NCT02571166?term=sanofi&cond=herpes+simplex+virus&cntry=US&rank=2

[Freefalling87]

6 hours ago, Daisy777 said:

I have found this link please check:

https://clinicaltrials.gov/ct2/show/NCT02571166?term=sanofi&cond=herpes+simplex+virus&cntry=US&rank=2

That link is referencing phase 1. They have not yet released the results of phase 1 (that I am aware of). 

[justanothersufferer]

On 6/13/2018 at 10:13 AM, Freefalling87 said:

That link is referencing phase 1. They have not yet released the results of phase 1 (that I am aware of). 

Correct!

[Voyager2]

The first HSV529 phase 1 safety trial of 69 subjects ran from July 2013 to March 2017,

https://clinicaltrials.gov/ct2/show/NCT01915212

and evidently led to the vaccine being pronounced safe.

But then a second phase 1 safety trial (as referenced above in this thread) was launched in November 2015 with 10 subjects and is supposed to be completed in December 2018 - which is 6 months from now.

So they clearly want to be doubly sure this live vaccine is safe before moving on to phase 2. It's a shame it's taking so long but at least they haven't given up.

If the very promising Einstein and trivalent vaccines also find their way into clinical trials, we'll have a real horse race.

 

Edited June 21, 2018 by Voyager2

[Shandawgs]

12 hours ago, Voyager2 said:

The first HSV529 phase 1 safety trial of 69 subjects ran from July 2013 to March 2017,

https://clinicaltrials.gov/ct2/show/NCT01915212

and evidently led to the vaccine being pronounced safe.

But then a second phase 1 safety trial (as referenced above in this thread) was launched in November 2015 with 10 subjects and is supposed to be completed in December 2018 - which is 6 months from now.

So they clearly want to be doubly sure this live vaccine is safe before moving on to phase 2. It's a shame it's taking so long but at least they haven't given up.

If the very promising Einstein and trivalent vaccines also find their way into clinical trials, we'll have a real horse race.

 

Starting to get abit of hope thank you for this post! Finger crossed

[HerpesDumbAf]

So this is just preventing not even curing? I’m so done with the science world at this point 

[Heal World]

We all leave messages on Facebook to Bill Gates, Sun Yatsen Softbank Group, Alibaba Mayun, and other entrepreneurs, and send them emails, hoping they can help us. I know that my own personal power is limited, and I hope that each of us can take positive actions so that we can get their help within a short time.

[IamPositive]

On 6/22/2018 at 3:13 AM, Shandawgs said:

Starting to get abit of hope thank you for this post! Finger crossed

Finger crossed!!! At least the big name like Sanofi Pasteur won’t have difficulty regarding finance. I do really hope this vaccine would be success...

[HerpesDumbAf]

What is this vaccine supposed to do..

[Hockeyawesome1]

On 6/21/2018 at 1:49 AM, Voyager2 said:

The first HSV529 phase 1 safety trial of 69 subjects ran from July 2013 to March 2017,

https://clinicaltrials.gov/ct2/show/NCT01915212

and evidently led to the vaccine being pronounced safe.

But then a second phase 1 safety trial (as referenced above in this thread) was launched in November 2015 with 10 subjects and is supposed to be completed in December 2018 - which is 6 months from now.

So they clearly want to be doubly sure this live vaccine is safe before moving on to phase 2. It's a shame it's taking so long but at least they haven't given up.

If the very promising Einstein and trivalent vaccines also find their way into clinical trials, we'll have a real horse race.

 

What type of vaccine is this? A therapeutic vaccine? Or is it a functional cure where it stays dormant?

[IamPositive]

6 hours ago, Savannah069 said:

What is this vaccine supposed to do..

Keep the healthy one immune to our virus/prophylactic.

[IamPositive]

6 hours ago, Hockeyawesome1 said:

What type of vaccine is this? A therapeutic vaccine? Or is it a functional cure where it stays dormant?

I guess it would be like Current HPV vaccination.. to protect the uninfected person has ability to combat the virus and stay clean.

[HerpesDumbAf]

5 hours ago, IamPositive said:

Keep the healthy one immune to our virus/prophylactic.

It’s funny how HIV the actual death sentence isn’t even stigmatized as this which is blowing me

[Visitorette]

2 hours ago, Savannah069 said:

It’s funny how HIV the actual death sentence isn’t even stigmatized as this which is blowing me

You're right. They feel more sorry for them while they did the same thing as us to aquire it; having sex.

[Zero6283]

It does bug me...... hiv has no risk of transmission and normal life expectancy if caught early and on medication....... hsv has literally nothing to prevent transmission.......

[brookeb300]

I think they r so scared of aids that they are really trying to cure it while herpes they look at as almost a joke

[HerpesDumbAf]

2 hours ago, Visitorette said:

You're right. They feel more sorry for them while they did the same thing as us to aquire it; having sex.

 

1 hour ago, Zero6283 said:

It does bug me...... hiv has no risk of transmission and normal life expectancy if caught early and on medication....... hsv has literally nothing to prevent transmission.......

 

12 minutes ago, brookeb300 said:

I think they r so scared of aids that they are really trying to cure it while herpes they look at as almost a joke

The fact that catching HERPES is high risk for AIDS you would think there would be a cure by now or something to stop transmission I’m just saying 

[IamPositive]

6 hours ago, Savannah069 said:

It’s funny how HIV the actual death sentence isn’t even stigmatized as this which is blowing me

So agree with you.. just because theoretically we could live longer than HIV patients.. but it’s the “theory”... the reality.. I believe so many of us want/already end their life because of this “creep”y virus. So we ain’t get any longer life expectancy to be honest...

[IamPositive]

4 hours ago, Visitorette said:

You're right. They feel more sorry for them while they did the same thing as us to aquire it; having sex.

[Voyager2]

@hockeyawesome1, this link implies HSV529 is a preventive vaccine (for the uninfected):

https://en.wikipedia.org/wiki/Herpes_simplex_research

I'm rooting for the 4th and 5th ones down, but they're unfortunately still in animal studies.

[oneday]

Anything from Sanofi on their vaccine?

[MikeHerp]

On 2/2/2019 at 5:33 PM, oneday said:

Anything from Sanofi on their vaccine?

I think the trial finished a couple of weeks ago.  I don't know when or whether they'll publish results.  

[jeraldpeabody]

@MikeHerp have you been following the HSV-2 ΔgD-2 research at all? Apparently, they're working with a company on it but I can't find any further information on it. Wondered if you might have any further info?

 

Edited February 5, 2019 by jeraldpeabody
updated video link

[StayingUpbeat]

The Betsy C. Herold, MD delta GD-2 vaccine is being pursued by a company called x-vax

https://x-vax.com/

"We’ve begun to transfer the vaccine ∆gD-2 from the research lab to manufacturing facilities for further development and production, and to prepare for a Phase 1 clinical study."