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viralfrog

Over 4 Years with HSV-2, Symptoms Keep Getting Worse with Non-Stop Outbreaks Despite Suppressive Therapy (Need HELP!)

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Throwaway1389

I read on here recently that HTP-5 could be the possible culprit. Not sure who posted but try cutting that out. 

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Lulupazoola

Good luck to u viralfrog.  I really hope the vitamin C works for u, as, thankfully, it is cheap.  Hopefully, you purchased ascorbic acid.  There is another form of vitamin C and it never occurred to me to post until recently that the form I am using and assume other vitamin C users r using is ascorbic acid.  It is the kind most commonly used.

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Skrillah80

Anybody know about genital warts

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Girl001

Maybe it could be the stress your putting on your body? I know I get a breakout when I stress out. 

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viralfrog

Thanks guys for the replies, adding a little update here so I can keep a nice log of all my experiments in one place. So far no luck, still having outbreaks daily. 

I recently did an experiment with Amenalief at 100mg/day without success:


Now I'm testing a megadose of Ascorbic acid; around 6g in powder form diluted to water, twice daily. 

On 3/1/2019 at 11:00 PM, Throwaway1389 said:

I read on here recently that HTP-5 could be the possible culprit. Not sure who posted but try cutting that out. 

That was actually myself who posted that thread. I did a test and stopped it for one month but saw no improvement. 

On 3/2/2019 at 6:04 AM, Lulupazoola said:

Good luck to u viralfrog.  I really hope the vitamin C works for u, as, thankfully, it is cheap.  Hopefully, you purchased ascorbic acid.  There is another form of vitamin C and it never occurred to me to post until recently that the form I am using and assume other vitamin C users r using is ascorbic acid.  It is the kind most commonly used.

Thanks, yeah I'm just trying it right now. 

On 3/5/2019 at 6:44 PM, Girl001 said:

Maybe it could be the stress your putting on your body? I know I get a breakout when I stress out. 

I have tried also up to 3-4 week period taking rest from most physical activities, but no luck with that. Weight lifting / gym training is a very important part of my life that I don't want to lose. 

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viralfrog

Update: I stopped antivirals completely a few days ago. I'm now eating Ascorbic acid around 12g/day and added NAC 1000mg/day as I had some in my closet (originally bought for avoiding hangovers). I'm actually starting to feel better now. Still some redness, but I don't feel as lethargic as usual. I actually feel pretty alright for the last days!

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Lulupazoola
4 hours ago, viralfrog said:

Update: I stopped antivirals completely a few days ago. I'm now eating Ascorbic acid around 12g/day and added NAC 1000mg/day as I had some in my closet (originally bought for avoiding hangovers). I'm actually starting to feel better now. Still some redness, but I don't feel as lethargic as usual. I actually feel pretty alright for the last days!

Glad to hear!  I bought some liposomal C, 1 bottle of gelcaps and one box of packets and am slowly switching over from ascorbic acid while i learn how to make it.  Sooner or later u r going to have gas and diarrhea from the AA, which does not happen with liposomal.  (Of course, u can just back off the dose that is doing that to u.)  Also, its a lot to keep track of, trying to take all that vitamin c throughout a busy day.  I think with liposomal that is not as critical, u could probably take it just 2 or 3 times a day, and it makes sense to me that u would not need to take as much either, since you actually absorb it in that form so much better.  Im really glad to hear u are feeling better!

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viralfrog
5 hours ago, Lulupazoola said:

Glad to hear!  I bought some liposomal C, 1 bottle of gelcaps and one box of packets and am slowly switching over from ascorbic acid while i learn how to make it.  Sooner or later u r going to have gas and diarrhea from the AA, which does not happen with liposomal.  (Of course, u can just back off the dose that is doing that to u.)  Also, its a lot to keep track of, trying to take all that vitamin c throughout a busy day.  I think with liposomal that is not as critical, u could probably take it just 2 or 3 times a day, and it makes sense to me that u would not need to take as much either, since you actually absorb it in that form so much better.  Im really glad to hear u are feeling better!

Currently I'm taking my Ascorbic acid at two doses throughout the day, 6g at lunch and 6g at dinner. It's already a hassle as I have to dilute it in water, rinse my mouth with coconut oil and then I take a shot of it from a shot glass and rinse my mouth quickly with water after. Even with the coconut oil, I'm worried for my teeth. 

I was going to order a capsule filler machine and some gelatin capsules, but realised it will cost me almost the same than just ordering 1g vitamin tablets from iHerb. Also, this means I still have to be eating 12 capsules per day which is not ideal. I wonder if I could figure out some DIY method to be able to squeeze 3-5g of the Ascorbic acid into some coating to be able to swallow it without risking my teeth. 

I had a look at liposomal C too, but what put me off was the quick expiration date if making it yourself. Unless I'm wrong, you have to do a new batch like twice a week. 

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WilsoInAus

Hang on @viralfrog let’s be rational here.

The male body can only usefully metabolise 100mg of vitamin C a day. Any excess does not have any known impact on the body as it doesn’t actually get to where you might be thinking it goes. It goes out via your kidneys, potentially causing toxic effects.

The real trick with vitamin C is making sure there is a good flow moving through your intestines such that your body can metabolise the full 100mg easily. To achieve this, you are much better off taking a tablet of about 250mg with each meal.

Anything more than 2g a day of vitamin C is not only useless but commences a strain process on your body that may include outcomes including kidney stones. 

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viralfrog
6 minutes ago, WilsoInAus said:

Hang on @viralfrog let’s be rational here.

The male body can only usefully metabolise 100mg of vitamin C a day. Any excess does not have any known impact on the body as it doesn’t actually get to where you might be thinking it goes. It goes out via your kidneys, potentially causing toxic effects.

The real trick with vitamin C is making sure there is a good flow moving through your intestines such that your body can metabolise the full 100mg easily. To achieve this, you are much better off taking a tablet of about 250mg with each meal.

Anything more than 2g a day of vitamin C is not only useless but commences a strain process on your body that may include outcomes including kidney stones. 

I think you're right about 'having a good flow', i.e. splitting the dosage throughout the day to make most use of it. You're also right about potential strain on your body for overdoses, however there is conflicting information about this based on studies I've read. There are several of studies indicating benefits of high doses of vitamin C for fighting viral diseases. I've done quite a bit of research on this as in the past I used to suffer from common colds, often over one week in duration and up to 6 times a year. With Zinc and Vitamin C I've managed to reduce these to once a year, and their duration to under 6 days. Some of the studies used IV administration of Vitamin C, which is of course different to taking it orally, but some of them had success with high oral doses as well: 

Dr. Harri Hemilä from the University of Helsinki, Finland, analyzed the findings of two randomized trials each of which investigated the effects of two vitamin C doses on the duration of the common cold. The first trial administered 3 g/day vitamin C to two study groups, 6 g/day to a third group, and the fourth group was administered a placebo. Compared with the placebo group the 6 g/day dose shortened colds by 17%, twice as much as the 3 g/day doses did. The second trial administered 4 g/day and 8 g/day vitamin C, and placebo to different groups, but only on the first day of the cold. Compared with the placebo group, the 8 g/day dose shortened colds by 19%, twice as much as the 4 g/day dose did. https://www.mdpi.com/2072-6643/9/4/339/htm

High dose IV Vitamin C has been shown to be effective against viral infections such as the common cold rhinovirus (Hemila and Herman,1995); avian virus H1N1 (Ely,2007;) Chikungunya (Gonzalez et al. 2014; Marcial-Vega et al,2015); Zika (Gonzalez et al 2016) and influenza (Zarubaeva et al.2017). Also oral supplementation with vitamin C (doses over 3g) appears to be able to both prevent and treat respiratory and systemic infections (Carr and Maggini, 2017). https://isom.ca/article/high-dose-vitamin-c-influenza-case-report/

We had a case in which a patient with herpes zoster did not respond to conventional therapy so we attempted to administer intravenous infusion of vitamin C which resulted in an immediate reduction in the pain. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111558/

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IcantThinkofaName
On 4/19/2019 at 11:42 AM, viralfrog said:

Update: I stopped antivirals completely a few days ago. I'm now eating Ascorbic acid around 12g/day and added NAC 1000mg/day as I had some in my closet (originally bought for avoiding hangovers). I'm actually starting to feel better now. Still some redness, but I don't feel as lethargic as usual. I actually feel pretty alright for the last days!

NAC is pretty good for lots of stuff...detox, heavy metals I think too. keep us posted!!

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Lulupazoola
On 4/19/2019 at 10:00 PM, viralfrog said:

Currently I'm taking my Ascorbic acid at two doses throughout the day, 6g at lunch and 6g at dinner. It's already a hassle as I have to dilute it in water, rinse my mouth with coconut oil and then I take a shot of it from a shot glass and rinse my mouth quickly with water after. Even with the coconut oil, I'm worried for my teeth. 

I was going to order a capsule filler machine and some gelatin capsules, but realised it will cost me almost the same than just ordering 1g vitamin tablets from iHerb. Also, this means I still have to be eating 12 capsules per day which is not ideal. I wonder if I could figure out some DIY method to be able to squeeze 3-5g of the Ascorbic acid into some coating to be able to swallow it without risking my teeth. 

I had a look at liposomal C too, but what put me off was the quick expiration date if making it yourself. Unless I'm wrong, you have to do a new batch like twice a week. 

It is already a hassle getting started with making it.  I end up with more questions than I can find answers for, but stumble on...  I am retired so feel like my job is (finally) taking care of myself.  I have had few health issues, generally healthy--except for the H bomb.  If i have to make liposomal 2x a week, i dont think it will be a big deal.  The big deal is getting the equipment and getting started i think.  I make kombucha, which is sort of like having a not-very-demanding pet.  I dont mind doing this kind of stuff.  But will probably keep liposomal capsules or packets on hand for times when its inconvenient to make it. I cant believe u r sucking down 6 g of AA at a time!  The most i drink with AA is 2 g at a time.  I am currently taking 4 g AA and 9 g liposomal C in caps/packets. The protocol evolves.  I am so thrilled to not have BO's that i dont care what i have to do. They ruined my life.  I am glad u r finally getting good results with your fight against H.  Have u tried drinking the AA thru a straw with the straw toward the back of your mouth to avoid teeth?  I would think baking soda and water swished around in your mouth after drinking the AA would neutralize any remaining acid.  My teeth have pretty strong enamel, so i dont worry about it (but dont do 6 g AA at a time).  If u r worried about acid erroding tooth enamel, why arent u worried about 6 g of AA at a time going down the soft tissues of your esophagus and onward?  Im not saying its wrong, just wondering.   

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viralfrog

@Lulupazoola I have tried with a straw but it's difficult to create enough suction if the straw is deep enough in your throat :D After drinking 6g from a shotglass I immediately drink a glass of water to dilute it down the throat. 

Little update: blisters, redness and lethargy are back today. I'm still off the antivirals completely and my outbreaks are not any worse than usual for now. That's interesting, it seems I don't react at all to Acyclovir


 

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WilsoInAus

@viralfrog given your symptoms do not react to any known antiviral doesn thatvsuggest these are not herpes lesion? 

Lets apply Occam’s razor here.

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viralfrog
3 hours ago, WilsoInAus said:

@viralfrog given your symptoms do not react to any known antiviral doesn thatvsuggest these are not herpes lesion? 

Lets apply Occam’s razor here.

I would not be the first one, plenty of others here on the forum who get recurrent OBs despite heavy doses of antivirals. The blisters appear exactly in/around the spot where I had my first OB 4 years ago, plus all the symptoms I have are those commonly described as HSV-2 symptoms. In my opinion, it's a clear case. 

But your suggestion is definitely an option that should not be ruled out. I'll wait until I get a bad enough OB again so I can go get another swab test. The outbreak needs to be bad enough to be able to break the blisters to get the liquid from inside right? I recall hearing something like this when I got tested years ago. The doctor used a swab that had tiny needles on it that would pop the blisters open. Do you know if this is right, i.e. you will not get a positive swab just from a mild OB / redness? 

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Lulupazoola

Am very sorry to hear of your recent OB.  You might try a box/bottle of liposomal vitamin C, which apparently has a much higher absorbtion rate than ascorbic acid.  Maybe u can get a better response from that.  Something to try.  

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viralfrog

Just a little update here, went for an urinalysis to check for UTIs or any other bacteria visible from urine. Everything came back as clean and negative. Otherwise, same same as before, mostly keep getting mild outbreaks with some better days in between. Seems to be a clear connection with stress; had some better days after taking a holiday but now back to very stressful work situations resulting in poor sleep and frequent OBs

This is for a completely unrelated problem, but today I started injecting myself with a research peptide called BCP-157. The purpose of this is to assist healing a chronic tricep tendonitis. A reported "side effect" of this drug is improved immune system, so thought it's worth adding this to my log in case it has any kind of effects. 

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Lulupazoola

I think its good that u keep trying things. Hopefully at some point, u will find something that brings u some relief.  Lots of people do.  I know u r a difficult case, but i would say i am too, and eventually, i tried something that works for me.  Maybe this will be it. 

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viralfrog

Little update mainly for my own logging purposes. On Friday I switched my TRT protocol to using Testosterone Enanthate instead of Unecanoate (Nebido) for price reasons. As I still had some of the existing medication in my system I got a spike in estrogen and now I have pain in my nipples. I started using Arimidex to reduce E2 levels for now. 

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IcantThinkofaName
On 5/3/2019 at 8:11 AM, viralfrog said:

Seems to be a clear connection with stress; had some better days after taking a holiday but now back to very stressful work situations resulting in poor sleep and frequent OBs

Sounds like cortisol problem or adrenal fatigue. Did you look into that at all?

adrenal issues can affect sleep too and hormone levels

I have this problem... and after a hard workout my adrenals are stressed and cortisol rises and BAM, a breakout

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IcantThinkofaName
On 5/7/2019 at 10:52 AM, viralfrog said:

Little update mainly for my own logging purposes. On Friday I switched my TRT protocol to using Testosterone Enanthate instead of Unecanoate (Nebido) for price reasons. As I still had some of the existing medication in my system I got a spike in estrogen and now I have pain in my nipples. I started using Arimidex to reduce E2 levels for now. 

I think you have a really hard way to go, because hormonal fluctutations also cause outbreaks  and since you are on hormone replacements, those seem hard to get right. Can a Dr help you get it right ?  I am certain that it has something to do with your Outbreaks. Are they all synthetic hormones? Maybe try bioidentical???( Maybe you already have/are, I don't remember now)

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viralfrog
11 hours ago, IcantThinkofaName said:

Sounds like cortisol problem or adrenal fatigue. Did you look into that at all?

adrenal issues can affect sleep too and hormone levels

I have this problem... and after a hard workout my adrenals are stressed and cortisol rises and BAM, a breakout

I have not looked into this, although I did read about it before when researching reasons for lethargy alone. I might go for a full blood test soon. Reading about this stuff just now also made me look into vitamin D deficiency. I actually live in a very sunny and hot country (Thailand), however I avoid the sun like the plague! I mostly work indoors and wear a light jumper, balaclava and gloves when I go out (I travel by motorcycle, just to mention before someone imagines a person walking on the street fully covered like some weirdo ;D ). Whenever I go to the beach I wear SPF 50 sun lotion. 

10 hours ago, IcantThinkofaName said:

I think you have a really hard way to go, because hormonal fluctutations also cause outbreaks  and since you are on hormone replacements, those seem hard to get right. Can a Dr help you get it right ?  I am certain that it has something to do with your Outbreaks. Are they all synthetic hormones? Maybe try bioidentical???( Maybe you already have/are, I don't remember now)

I see a specialist yearly, but he always recommends me to do what I would have alredy done myself. Measuring one's levels is easy, however the recommended ranges are quite wide. Therefore, levels that feel good for one person don't mean they'd work on another one. So the only way for me really is to experiment and find a level that I feel good at. However, I highly suspect the effects I've correlated with hormone problems in the past are in fact caused by the HSV. It is likely though, that my outbreaks are related to the fluctuating hormone levels. 

I don't think such thing as bioidentical testosterone exists and the term in general seems to be something that's not recommended by medical professionals. I believe decades ago testosterone was made by extracting it from animals, however nowadays, it is all synthetic and used my hundreds of thousands without issues. 

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ruth234
how my husband was saved from herpes , i decided to reach out to those still suffering from this diseases.
He was having this diseases for 6 months and it was really tough and heartbreaking for me as his wife i could not have sex with him, we have spend a lot but the symptoms were terrible, we tried various prescribed by our doctor but non could cure him. I searched for a cure and i saw a testimony by someone who was cured and so many others with similar body problem, and he left the contact of the doctor who had the cure to herpes.I never imagine herpes has a cure not until i contacted him and he assured me my husband will be fine. I got the herbal medication he recommended and I used it and he was fully okay even up till this moment he is so full of life. herpes has a cure and it is a herbal cure contact the doctor for more info on drokosunmusa@gmail.com or   whatsapp him on +2349056175191  on how to get the medication. Thanks for reading my testimony
 should clink on dr okosun website link for more info   https://drokosunmusa.wixsite.com/my-herbs  

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Eastern

ViralFrog- I noticed in your original post that you mentioned that you regularly consume whey protein. Whey protein is one of two foods that I must completely avoid (the other is cashews fwiw). Any consumption of whey protein and I get an ob

I’ve been lurking here recently and this is my first post, but thought I’d pass on my experience in case it may help you. 

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Kurdt01

Saw Palmetto (Natures finestride) seems like a trigger for me....Was taking for thinning hair, but every time I take it, it causes OB's.

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