Jump to content

Non-stop outbreaks


Recommended Posts

I got diagnosed around May this year with Hsv2. My first outbreak felt like the flu (swollen lymph nodes, tiredness, body aches) and eventually I got a huge painful cut below the opening of my vagina with one maybe two small sores that didn't hurt. My obgyn prescribed valtrex and a steroid creme (I think?) just for the cut. I decided to stay on valtrex daily and I increase it to twice a day during breakouts. (I know steroids cause herpes flare ups, I can't remember off of the top of my head what she gave me but it didn't make things worse, it healed the cut quickly.) It cleared up within a week and I didn't really have any problems with hsv2 for about two months after that. Then August came around and school started back up for me. I have had continuous non-stop breakouts since and it's been AWFUL. 

The first week of August I had a breakout of around 3 sores and they took about two weeks to heal. A week after that, another one popped up. It was about the same number or sores but in different spots and took about two weeks to heal as well. A week after that I had another breakout. Basically the point I'm getting at is that my breakouts have gone from being months apart, to weeks apart, and have began overlapping each other now. The sores are bigger, more painful, in different spots, and I've gone from having 1-3 in a breakout to around 10-15 and they don't seem to be healing but rather getting more inflamed. 

My theories for what could be attributing to this is the shift in my stress levels? I work full time and go to school (so basically stressed all of the time because of school and bills lol.) and I know that can't be helping. I take valtrex twice a day as well as vitamin B, C, CBD oil, and use tea tree oil on active sores- which helps relieve a little bit of pain. I also realized that my nexplanon implant might be a culprit? I will have had it for three years in February (three years is the length of effectiveness). Is it wearing off and causing a hormone imbalance/shift in turn causing these awful breakouts?? 

I have an appt with my obgyn in a couple of weeks but I'm miserable right now. Valtrex doesn't seem to be helping at all. The nerve pain has always been awful for me and sometimes I can't sleep because of it. I also have noticed my motor coordination is worse and my muscles constantly twitch because of it. It makes me wonder if there's an underlying condition such as an autoimmune disorder that is preventing my immune system to fully fight the virus? I already have been diagnosed years ago with Raynaud's syndrome and a folic acid deficiency-could those be contributing factors as well? (If I'm honest I do not take the L-methylfolate that I'm supposed to and I know I should. I stopped it about a year ago out of laziness.) 

Just looking for some opinions or answers on the topic. Obviously I need to get into a doctor but until then I'm curious what others have to say. I'm starting to feel hopeless :( 

 

 

Link to post
Share on other sites

Its hard finding the right dr.  I had been to 1 dermatologist and 2 general practitioners.  I tried valacyclovir, which lowered my platelets so they took me off, but really didnt know what to do with me.  I suggested to my dr maybe an infectious disease specialist?  But she sent me to an immunologist instead.  He is trying to help me out.  So in my experience, i cant really recommend a general practitioner.  Maybe u could ask what kind of dr people have been helped most by.  If u have not tried l-lysine, i would try that, and i would try oregano oil externally.  These r both fairly harmless and would give u something to try at least.  There r other antivirals to try that may help but u have to have a dr who knows about treating herpes.

Link to post
Share on other sites
  • 2 years later...

I've had a very similar experience to yours - initial flu-like outbreak in July, nothing for 2 months, and then non stop outbreaks for about the past month and a half. I think sex is a trigger which is upsetting, affecting my confidence and don't like knowing in the back of my mind that the aftermath of any time I have sex will be an OB. Any solutions for anyone here on how to keep an OB from happening from sex? Heard lube can be a best friend but just feeling slightly hopeless on this. Hope you're feeling better :)

Link to post
Share on other sites
  • 2 weeks later...

Do your research.  Yes stress makes it worse. Lack of sleep makes it worse. Autoimmune disorders make it worse. Find something you enjoy that is relaxing to you. Possibly counseling. Talk to a close friend.  Try the l lysine,  maybe a stronger dose of valtrex ,anti depressants or anti anxiety medications help. Take care of you! Gabapentin helps with nerve pain. There is alot more that can be done for you. You have to push your dr. I was having outbreaks on top of outbreaks when I was first diagnosed and I have only had 1 since starting suppressive therapy and adding some vitamin supplements and working on decreasing my stress. I could have stopped that outbreak but I didn't know  I could take my valtrex 3 times a day and I didn't recognize the proteome symptoms quickly enough.  I know better now! Take care! I hope this helps!

Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.



  • Donate

    If Honeycomb has helped you, please help us by making a donation so we can provide you with even better features and services.

  • The Hive is Thriving!

    • Total Topics
      71,957
    • Total Posts
      486,520
  • 0_unsure-if-it-is-herpes.png

    Nervous about dating with herpes? Skip "the talk" and browse profiles here.

  • Posts

    • CHT
      so, you tested positive for GHSV1 via the swab test?  Not by an IgG antibody blood test? Are the OBs severe?  Are they coming often?    GHSV1 in its initial stages (early infection) can cause outbreaks.... the good news is that your odds of outbreaks is significantly lower than those with HSV2 and the number of outbreaks are also much less with GHSV1 than HSV2 especially as time goes on.... on average you may see only one outbreak per year versus 4 to 5 for those with HSV2.... the severity of the outbreaks from GHSV1 are also milder than HSV2 (you may not even notice them with time or go completely asymptomatic).  You may not even need antivirals as time goes on. 
    • Liv25
      The chapstick is called Docoshield and it is on Amazon. Just wanted to pass this along! I have been using this and it brings me a lot of comfort and it has excellent reviews. They also made this chapstick with lysine in it. Hope this helps anyone who needs it! 
    • BabyGirl
      I just stared dating someone who does not have HSV.How long after the sore is healed should I wait before having sex?  I’ve had HSV2 for over 10 years. I rarely have outbreaks going months even years until recently. When I do I get some tingles and one sore in the same spot. But recently, In the last 3 months it’s happened twice. 🤦🏼‍♀️
    • JDMT_176
      If you want to know whats going on when applying it, this was the only study I found describing it. Hard to read through as very technical, but am copy paste parts I found of use. Tables also useful to show which genes are expressed more.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416766/   "A petrolatum donut was applied with a cotton swab to form about a 1 cm diameter donut on skin on the inner aspect of the upper arm. Then a separate cotton swab was dipped in a 2% SADBE solution (w/v) in DMSO, and the swab was then used to apply about 10–20 mg of solution over about a 1 cm diameter circle within the petrolatum donut. Immediately after application, the application site was covered with TEGADERM. Subjects were advised to remove the TEGADERM and rinse and wipe the spot 3 h later.   "Thus in essentially every case, the SADBE treatment changed the group A subjects by day 57 to make them much more like the group B and C subjects who have better immune control of their HSV‐1 infection than the group A subjects were on day 1.   "Others have previously shown that CD8+ T cells are important in controlling herpes labialis outbreaks.23, 24, 25, 26, 27, 28, 29, 30, 31, 32 Our data are consistent with this. The helper/cytotoxic cell ratio (CD4+/CD8+ ratio) was 5.25 in group A versus 3.07 and 3.15, respectively in groups B and C (Table (Table3).3). The P‐value is less than 0.20 for comparisons of group A to both groups B and C, and if groups B and C are pooled and compared to group A the P‐value is 0.065, almost significant. This is consistent with prior evidence discussed below that CD8+ T cells are important and effective in controlling HSV recurrences.   "Consistent with our finding lower anti‐HSV‐1 IgG levels correlate with better control of HSV‐1 outbreaks, Spruance et al. also found lower serum anti‐HSV‐1 antibodies in HSV seropositive patients with a history of frequent herpes labialis than in seropositive persons with no history of herpes labialis.33   "Several prior reports also found IFN‐gamma to be important in controlling HSV infection and reducing HSV outbreaks. Dobbs et al28 showed that CD8+ T cells were able to clear an HSV‐2 infection in transgenic mice, but that efficacy was blocked in vivo by anti‐IFNG IgG. Liu et al31 showed that CD8+ T‐cells could prevent HSV‐1 reactivation from latency in excised trigeminal ganglia (TG), and that IFN‐gamma protein was produced by the CD8+ T cells, and that neutralization of IFN‐γ significantly enhanced the rate of HSV‐1 reactivation from latency in TG cultures. Spruance et al33 found that IFN‐gamma protein levels in PBMC supernatants stimulated with HSV‐1‐infected cell extracts were lower in frequent herpes labialis sufferers than HSV‐1 seropositive controls, consistent with the present result for IFNG gene expression in PBMC stimulated with heat‐killed HSV‐1. McKenna et al7 assayed IFN‐gamma in medium of PBMCs cultured in vitro and stimulated with inactivated HSV‐1 and found IFN‐gamma was at higher concentrations in medium of PBMCs from infrequent herpes labialis sufferers than frequent sufferers, also consistent with our findings. Cunningham et al34 showed higher interferon levels (including alpha, gamma, and lambda) in supernatants of PBMCs stimulated with heat‐killed HSV‐1 virus correlated with longer time to next herpes labialis recurrence. Carr et al35 showed that transgenic expression of IFNG could prevent HSV‐1 reactivation in a mouse model.
    • JDMT_176
      Hi Kurdt- I was thinking back in 2018-2019 there was several threads from viral frog that he was applying a 2% solution very frequently. Like several times a week. From what I gather- it didnt work for him at the time. I think too much applied caused immune chaos or something.  The most recent Square X trial was terminated but this was the dosing frequency that was used in the trial below: I was planning on using Group C protocol. Group A is most frequent. Something to think about.  https://clinicaltrials.gov/ct2/show/results/NCT03521479?term=squarex&draw=1&rank=4   Protocol:  Arm/Group Title Group A Group B Group C Group D  Arm/Group Description Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 2% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 0.5% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0, month 3, and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months).   Adverse Reaction Table: Arm/Group Title Group A Group B Group C Group D  Arm/Group Description: Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 2% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 0.5% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0, month 3, and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Overall Number of Participants Analyzed 10 10 10 10 Measure Type: Number Unit of Measure: events         Localized reaction (rash, erythema, itching/pruritus, warmth/burning) at application site 24 14 17 6 Generalized adverse events (related, possible or greater) 2 3 1 0 Generalized adverse event (unrelated) 4 7 6 4  
×
×
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.