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Voyager2

Anything more on Friedman's trivalent vaccine?

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Voyager2

Dr. Harvey Friedman's prophylactic subunit trivalent herpes vaccine sounded very promising a few years ago. In Dr. Josh Bloom's Oct. 2017 article

 

https://www.acsh.org/news/2017/10/11/herpes-vaccine-update-interview-penns-dr-harvey-friedman-11940

 

Dr. Friedman (of the University of Pennsylvania) was still optimistic and indicated that human trials were about 18 months away. That's only 6 months from now. It's not a therapeutic vaccine but if it becomes available for potential partners, it would improve our lives a lot. I know we need to live our lives regardless of this virus.

If the trials show nearly 100% efficacy, I would think they'd try to speed things up and not make us wait another 10 long years!

 

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ManagingIllness

The trials take a long time, especially if you're checking a prophylactic. Think about it. They are checking to see if the therapy prevents transmission. How do you do that, knowing that you can't give people the therapy and then attempt to give them the disease? Well, you have to take a whole people that are in discordant relationships, give the negative partner the therapy, and then wait a whole lot of time. Since there is phase 1 -3, you have to do that process 3 times over. Then you have to collect the data and write up a paper to be submitted to a journal. That alone takes another year. So even if the trivalent vaccine works, and will be the vaccine we are hoping for, it's going to take about a decade just to verify that. 

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Hopefullyhopeless
On 1/14/2019 at 4:59 PM, ManagingIllness said:

The trials take a long time, especially if you're checking a prophylactic. Think about it. They are checking to see if the therapy prevents transmission. How do you do that, knowing that you can't give people the therapy and then attempt to give them the disease? Well, you have to take a whole people that are in discordant relationships, give the negative partner the therapy, and then wait a whole lot of time. Since there is phase 1 -3, you have to do that process 3 times over. Then you have to collect the data and write up a paper to be submitted to a journal. That alone takes another year. So even if the trivalent vaccine works, and will be the vaccine we are hoping for, it's going to take about a decade just to verify that. 

 

Tell us why it's going to take a decade again?

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ManagingIllness

Oh sorry, my bad, it's going to be out next year everyone. Vaccine 2020! We got this! Have fun and enjoy your lives everyone. Only 1 more year left!

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