Jump to content
World's Largest Herpes Support Group
Sign in to follow this  
ill47

Negative for HSV-2 and "indeterminate" for HSV-1 at 8 weeks.

Recommended Posts

ill47

How worried should I be about the "indeterminate" part? I got tested again at 12 weeks but not results back yet. Also, how likely is genital to genital HSV-1 transmission? Because the contact in question did not include oral.

Edited by ill47

Share this post


Link to post
Share on other sites
WilsoInAus

Hey @ill47

I'm quite worried about what test you have had here? Certainly not a Herpeselect test. Do you have a printout of it? Question whether it was actually an IgG test. I have only really seen indeterminate associated with Westernblot (that comes with a lot of antibody band information) and immunoblot style testing that is kind of like a pregnancy kit, look for the pink dot!

In terms of an indeterminate HSV-1 reading, there are three possibilities:

  1. Rogue proteins causing an elevated outcome.
  2. Childhood HSV-1 oral infection and you test at low IgG antibody levels
  3. Slow seroconverting, pretty rare most infected people record a strong result after 8 weeks.

What is exceptionally rare is not having lesions upon a primary infection of HSV-1 genitally - usually no doubt whatsoever.

Share this post


Link to post
Share on other sites
ill47
4 hours ago, WilsoInAus said:

Hey @ill47

I'm quite worried about what test you have had here? Certainly not a Herpeselect test. Do you have a printout of it? Question whether it was actually an IgG test. I have only really seen indeterminate associated with Westernblot (that comes with a lot of antibody band information) and immunoblot style testing that is kind of like a pregnancy kit, look for the pink dot!

In terms of an indeterminate HSV-1 reading, there are three possibilities:

  1. Rogue proteins causing an elevated outcome.
  2. Childhood HSV-1 oral infection and you test at low IgG antibody levels
  3. Slow seroconverting, pretty rare most infected people record a strong result after 8 weeks.

What is exceptionally rare is not having lesions upon a primary infection of HSV-1 genitally - usually no doubt whatsoever.

You're quite worried? Lol, calm down.

Yes I have a print out, it's an Immunoblot igg test. It says HSV-2 negative and HSV-1 indeterminate. It says "Band patterns do not allow accurate readings for HSV-1. Confirmatory testing is recommended in 4 to 6 weeks with a second serum sample." 

Edited by ill47

Share this post


Link to post
Share on other sites
ill47
21 minutes ago, WilsoInAus said:

That’s only relevant at 12 weeks.

For recent infections, detection is 95-100%.

What is only relevant at 12 weeks?

Share this post


Link to post
Share on other sites
ill47

What is the difference between sensitivity and specificity? Anyone know? Like some tests have stronger one than the other. What does that mean?

Share this post


Link to post
Share on other sites
ill47
2 minutes ago, WilsoInAus said:

The accuracy of the test.

I have no idea what you are saying or referring to. "The accuracy of the test." Okay... what? What about the accuracy of the test?

Share this post


Link to post
Share on other sites
WilsoInAus

Techies might use fancy terms, but what pragmatically we need to know is:

- what’s the chance of detecting an infection

- what’s the chance of a false positive.

At 12 weeks, a HSV-1 will be positive for 95-100% of infections.

Falae positives? Not sure, looks like somewhere between 10-25% of tests may have a false positive for people who are negative.

Share this post


Link to post
Share on other sites
ill47
11 minutes ago, WilsoInAus said:

Techies might use fancy terms, but what pragmatically we need to know is:

- what’s the chance of detecting an infection

- what’s the chance of a false positive.

At 12 weeks, a HSV-1 will be positive for 95-100% of infections.

Falae positives? Not sure, looks like somewhere between 10-25% of tests may have a false positive for people who are negative.

And at 9 weeks?

Share this post


Link to post
Share on other sites
ill47
1 minute ago, WilsoInAus said:

That’s over 90%, the last 10%seem to spread from weeks 8-12.

K, thanks. By the way, sensitivity refers to chances of a false negative and specificity to false positive. 

Share this post


Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Sign in to follow this  

  • The Hive is Thriving!

    • Total Topics
      69,536
    • Total Posts
      468,286
  • Posts

    • viralfrog
      I'm 99% confident that these are caused by Herpes. This is what they looked like when I first caught the virus, and in the same spots as well, although now much milder and smaller in size.  I have tested positive via swab when I first got the virus, and two times via blood test. However, since several people here are doubting my symptoms are caused by HSV, I might do another swab just to be sure. It's still good to rule anything else out beforehand. 
    • Nicki0605
      And btw  @ayekayelle I’m sorry you’re considering divorce. I hope you are able to work it out with him. But if you’re not happy I think it’s worth taking the risk of leaving! You deserve to be happy!
    • Nicki0605
      Ikr! I’ll have guys be like “oh yeah you’re right, you’re not gross or less valuable but it is a deal breaker” I don’t really blame them (because I am still coming to terms with it being “not a big deal”) 
    • G77
    • Quest
      It's very possible he or you were mostly a carrier. Neither one of you have to have sores all you have to do is shed.
×
×
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.