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landonjacobs

PCR Blood Test

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landonjacobs

My physicians office came back with results for my STI tests. For Herpes, they tested for active lesions using a “PCR blood test.” my understanding is that the only blood tests are IgG/IgM and PCR used swab testing. I clarified to make sure they spoke correctly. Has the standard changed recently? Can a blood test detect active lesions?

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WilsoInAus

You are correct that PCR is the wrong blood test to diagnose herpes.

Only the IgG test has credible results.

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landonjacobs
50 minutes ago, WilsoInAus said:

You are correct that PCR is the wrong blood test to diagnose herpes.

Only the IgG test has credible results.

Are you sure? why would they test me like that then? Surely they would know the correct way to test people.

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WannaCry

Nope. General Practitioner doctors spend very little time getting training on STD testing, and especially not much on something like HSV which is really not viewed as  life threatening (compared to say HIV, Syphillis, etc). HSV is one of the hardest STDs to correctly test for and there have been many advances in testing options in the years that they have probably graduated from medical school, and I can assure you that while they try they probably don't know the cutting edge options.

The PCR test issue happens very often. A Dr will remember they read 'PCR test' for HSV somewhere and send it off as a blood test. The PCR test for HSV is swab based - looking for viral DNA and a certain threshold of copies of that DNA from the suspected infected area. Blood PCR tests do not work for this. 

Other bad tests for adults are: IGM, crude antibody tests, Combined antibody tests. 

The only tests that should be done for determining HSV infection in adults are for blood the IgG or Western Blot and for swabbing the PCR or if during an obvious outbreak viral culture.

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    • IcantThinkofaName
      yes, get IGG testing ASAP, but be prepared for it to come back negative this first time if it is your first infection. A swab would be better if you have fresh blisters.  If they are already healed, and if its your first infection, be prepared for another subsequent OB (I'm sorry to tell you) coming soon after the first.. You can get swabbed at that one then.  Stay strong.  Support your immune system. Get rest. Take Vit. C and some other herbals might be nice...I have posted some stuff about that in the past. collodial silver gel or spray perhaps too directly on sores hugs to you
    • Sigh335
      No, no Custer. I pop it and it comes back. Thanks you so much for responding.
    • WilsoInAus
      @Franky26 your vows include "from this day forth" - there is no fine print that grants you annulment for previous actions and certainly not for the random assortment of herpes viruses that every person walks down the aisle with. To the extent that it was required (and I do not believe it is, although this is not relevant) your partner has been forgiven in the eyes of the Lord for all her past actions; as part of your marriage vows you are joined in that forgiveness. That blood test is notorious for false positives, Having an oral HSV-1 cold sore infection is a known risk factor for a false positive. So yes I do recommend obtaining a further ELISA test. You may even try to obtain the Westernblot from University of Washington for the definitive word on the subject.
    • WilsoInAus
      It is pretty definite he has HSV-2 so at least you will be concordant in that respect with no fears of passing it to him. Yes, there is a good possibility of some outbreaks within the first few months, however, this will not be a sign of your longer term experience which should improve tremendously.
    • Franky26
      Hey @WilsoInAus   Thank you for your reply, we live in north America, she did the test here in Canada, I will attach a copy of the test below. I understand your point of view but its hard for me to cope with this. I never thought this would happen to me which I m sure most people feel the same.  yes I did took vows for better or worst but I feel those vows are for whatever happens after marriage not because of something happened in the past.  i feel like this is something that is going to remind me of her past for the rest of my life. its not easy for me to look past that.   
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