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    • Kee
      By Kee
      This is just a chat for lesbians,as sex is a little different. 
    • MJ82
      By MJ82
      Please bear with me, because this is a bit detailed.
      About 6 months back, I tested positive for both HSV1 & 2 (IGG) after having a couple canker-like sores inside my mouth along with a couple of flat sores down there, which I noticed in the shower. When I was diagnosed, it was at a very stressful time in my life which must have lowered my immunity to produce my first symptoms in memory. My doctor was casual about my results, saying it was not something I needed to worry much about and that it was very common, and given I likely had this for years (anywhere from 6-12 years, given my sexual history and given that I have been celibate and single for 6 years). This was my first ever bout of mild symptoms, and he thought I might not necessarily have an outbreak again. I put it out of my mind and was relieved that my symptoms cleared up quickly. 
      A couple months after I was diagnosed, I met someone (a woman, I am a lesbian) who pursued me and things between us moved quickly. For the most part, we have only kissed a few times but one night we both had a bit to drink, and we ended up in bed briefly. For a very brief moment, the only contact she had with me is that she touched me down there (fingered me for less than half a minute), but she did touch herself at some point after. 
      A few weeks later, I noticed another small sore down there when I was in the shower, and I understood that I would need to share this with her if things were to progress, as I was having my first recurrence. I did some research on safe lesbian sex and herpes and was gutted to read that it can shed silently even without symptoms present. My ex-girlfriend used to occasionally get cold sores on her lip when stressed and I knew never to kiss her then, but I never imagined that this could be contagious without a visible sore present.
      I am absolutely distraught, and plan on speaking to her as soon as she is back from travelling. I am beside myself that I may have passed this on to her but want to approach the subject carefully and calmly with her so I don't completely freak her out, and also to arm myself with the facts. I have never been in a more miserable position in my life and could really do with some advice. She is the sweetest person and someone I began to really care about and have feelings for. I never would have knowingly put someone at risk, but I was completely under/misinformed about how this virus works.
      From everything I have now read, it seems like the risk to her would probably have been low, but at the moment my life has turned into a shell of what it was. Any advice on how to approach this talk would be greatly appreciated.
       
       
       
    • kat76
      By kat76
      I was curious if, when you have had oral herpes and you put your mouth on a girls vagina of that automatically would make them have a herpes outbreak? or if just because you have cold sores sometimes you should worry about having bad outbreaks ever? 
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    • CHT
      so, you tested positive for GHSV1 via the swab test?  Not by an IgG antibody blood test? Are the OBs severe?  Are they coming often?    GHSV1 in its initial stages (early infection) can cause outbreaks.... the good news is that your odds of outbreaks is significantly lower than those with HSV2 and the number of outbreaks are also much less with GHSV1 than HSV2 especially as time goes on.... on average you may see only one outbreak per year versus 4 to 5 for those with HSV2.... the severity of the outbreaks from GHSV1 are also milder than HSV2 (you may not even notice them with time or go completely asymptomatic).  You may not even need antivirals as time goes on. 
    • Liv25
      The chapstick is called Docoshield and it is on Amazon. Just wanted to pass this along! I have been using this and it brings me a lot of comfort and it has excellent reviews. They also made this chapstick with lysine in it. Hope this helps anyone who needs it! 
    • BabyGirl
      I just stared dating someone who does not have HSV.How long after the sore is healed should I wait before having sex?  I’ve had HSV2 for over 10 years. I rarely have outbreaks going months even years until recently. When I do I get some tingles and one sore in the same spot. But recently, In the last 3 months it’s happened twice. 🤦🏼‍♀️
    • JDMT_176
      If you want to know whats going on when applying it, this was the only study I found describing it. Hard to read through as very technical, but am copy paste parts I found of use. Tables also useful to show which genes are expressed more.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416766/   "A petrolatum donut was applied with a cotton swab to form about a 1 cm diameter donut on skin on the inner aspect of the upper arm. Then a separate cotton swab was dipped in a 2% SADBE solution (w/v) in DMSO, and the swab was then used to apply about 10–20 mg of solution over about a 1 cm diameter circle within the petrolatum donut. Immediately after application, the application site was covered with TEGADERM. Subjects were advised to remove the TEGADERM and rinse and wipe the spot 3 h later.   "Thus in essentially every case, the SADBE treatment changed the group A subjects by day 57 to make them much more like the group B and C subjects who have better immune control of their HSV‐1 infection than the group A subjects were on day 1.   "Others have previously shown that CD8+ T cells are important in controlling herpes labialis outbreaks.23, 24, 25, 26, 27, 28, 29, 30, 31, 32 Our data are consistent with this. The helper/cytotoxic cell ratio (CD4+/CD8+ ratio) was 5.25 in group A versus 3.07 and 3.15, respectively in groups B and C (Table (Table3).3). The P‐value is less than 0.20 for comparisons of group A to both groups B and C, and if groups B and C are pooled and compared to group A the P‐value is 0.065, almost significant. This is consistent with prior evidence discussed below that CD8+ T cells are important and effective in controlling HSV recurrences.   "Consistent with our finding lower anti‐HSV‐1 IgG levels correlate with better control of HSV‐1 outbreaks, Spruance et al. also found lower serum anti‐HSV‐1 antibodies in HSV seropositive patients with a history of frequent herpes labialis than in seropositive persons with no history of herpes labialis.33   "Several prior reports also found IFN‐gamma to be important in controlling HSV infection and reducing HSV outbreaks. Dobbs et al28 showed that CD8+ T cells were able to clear an HSV‐2 infection in transgenic mice, but that efficacy was blocked in vivo by anti‐IFNG IgG. Liu et al31 showed that CD8+ T‐cells could prevent HSV‐1 reactivation from latency in excised trigeminal ganglia (TG), and that IFN‐gamma protein was produced by the CD8+ T cells, and that neutralization of IFN‐γ significantly enhanced the rate of HSV‐1 reactivation from latency in TG cultures. Spruance et al33 found that IFN‐gamma protein levels in PBMC supernatants stimulated with HSV‐1‐infected cell extracts were lower in frequent herpes labialis sufferers than HSV‐1 seropositive controls, consistent with the present result for IFNG gene expression in PBMC stimulated with heat‐killed HSV‐1. McKenna et al7 assayed IFN‐gamma in medium of PBMCs cultured in vitro and stimulated with inactivated HSV‐1 and found IFN‐gamma was at higher concentrations in medium of PBMCs from infrequent herpes labialis sufferers than frequent sufferers, also consistent with our findings. Cunningham et al34 showed higher interferon levels (including alpha, gamma, and lambda) in supernatants of PBMCs stimulated with heat‐killed HSV‐1 virus correlated with longer time to next herpes labialis recurrence. Carr et al35 showed that transgenic expression of IFNG could prevent HSV‐1 reactivation in a mouse model.
    • JDMT_176
      Hi Kurdt- I was thinking back in 2018-2019 there was several threads from viral frog that he was applying a 2% solution very frequently. Like several times a week. From what I gather- it didnt work for him at the time. I think too much applied caused immune chaos or something.  The most recent Square X trial was terminated but this was the dosing frequency that was used in the trial below: I was planning on using Group C protocol. Group A is most frequent. Something to think about.  https://clinicaltrials.gov/ct2/show/results/NCT03521479?term=squarex&draw=1&rank=4   Protocol:  Arm/Group Title Group A Group B Group C Group D  Arm/Group Description Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 2% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 0.5% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0, month 3, and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months).   Adverse Reaction Table: Arm/Group Title Group A Group B Group C Group D  Arm/Group Description: Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 2% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 0.5% SADBE on the visits at week 3, week 6, week 9, and month 8. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0, month 3, and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and month 6. Squaric Acid Dibutyl Ester: Repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE) in subjects with frequent herpes labialis (4 or more episodes in the previous 12 months). Overall Number of Participants Analyzed 10 10 10 10 Measure Type: Number Unit of Measure: events         Localized reaction (rash, erythema, itching/pruritus, warmth/burning) at application site 24 14 17 6 Generalized adverse events (related, possible or greater) 2 3 1 0 Generalized adverse event (unrelated) 4 7 6 4  
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