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    • MikeHerp
      I'm excited about this vaccine and think it has a great chance to be approved.  However, this is not a "curative"vaccine. The vaccine is not "knocking out" the virus in the ganglia.  Rather, it is preventing the virus from reaching the ganglia when the virus newly infects a living thing.  Once the virus is in the ganglia, I understand this vaccine does not reach there.  This vaccine is not removing the latent HSV.  Rather, it's preventing it getting there in mice that were previously uninfected.  That's an important difference with the FHC work which is curative.  The work X-Vax has published recently is prophylactic work.   The vaccine may have therapeutic application--X-Vax has said it may.  But we will have to see further studies to see how much if any therapeutic user this will have.  
    • MikeHerp
      Recruitment Status  : Not yet recruiting   Not sure when this study will really start.  Hope it does though.  
    • MikeHerp
      I'd keep in mind the fact that AAVs produce an immune response.  So if you get this DIY thing, it may later be more difficult to benefit from the actual cure.  Dr. Jerome at FHC confirmed that, if you have been exposed to AAV, making it work on you again may require immune suppressants, etc.  FHC is using AAVs as well.  
    • WilsoInAus
      Hey @lar26 - well @Surfersparadise didn't read what you or I wrote. The situation is well beyond whether disclosure is an issue so it is not relevant in this context. It is a bit rich I have to say in receiving a lecture from someone with herpes who has not disclosed themselves for the bulk of their life. This is about making a rational decision on the basis of facts of the risks and what it means in a whole of life context. The odds are not an issue for the true decision your partner needs to make. If your partner cannot accept you as a person with HSV-1 orally, then sadly they can't and they are hence not the person for you. Unless someone is prepared to accept you for all that you are completely, then they are not partner material. You do not need to accept any compromise.
    • lar26
      @WilsoInAus thoughts on @Surfersparadise? I read up on an article that said risk of transmission while on antivirals is 1%. Combined with lysine, I haven't had an outbreak in forever.
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Giving ghsv1 to someone with oral hsv1

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Hey! So I’m a female with ghsv1 and my partner has type 1 oral herpes. What is the chance I give him Genital herpes or him give me oral herpes? 

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These are exceptionally low odds, so much so it really isn’t worthwhile worrying about.

Just enjoy a terrific sex life together!

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