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Clinical gene therapy for removing virus from cell 2019

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information seeker

Hello, fellow reader I am in the process of having the government of Canada start a experimental treatment to cure herpes. I have been following alot of the research sexual transmitted illiness, and have noticed good results for gene therapy. I reason to believe that herpes can be cured within the next 2 years. With an experimental gene treatment. With recent cure of cells with HIV using crispr cas9. I believe a cured can achieve using a cocktail of drugs and gene therapy.  The process works by forcing the virus to awaken, while pumping antiviral to stop the spread of the virus. This would allow crispr cas9 to more easily to shred the herpe's DNA in the cell. This would also be combined with a TRIM5α Proteins to prevent the spread replication of the virus. Alot of this optimism comes from the gene therapy treatment that show results with current gene therapy treatments that appears to be successful. I am currently looking for people who live in Canada and are citizens or permanent resident. To join me in the process. If this is successful after a 12 month to 24 months treatment, a subject may be cured of virus permanently. This could also pave the way for future cure in other viral infection like herpes.

 

Requirements 

Living in Canada 

Covered by national healthcare plan.

Willing to be part of experimental treatment.

 

Any one who does not meet these requirements can comment but may not be able to assist with the process.

 

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Skrillah80

Wow!! God I would sooo love a cure in 2 years.. Will this be available in the USA too? 

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35hope
22 minutes ago, information seeker said:

Hello, fellow reader I am in the process of having the government of Canada start a experimental treatment to cure herpes. I have been following alot of the research sexual transmitted illiness, and have noticed good results for gene therapy. I reason to believe that herpes can be cured within the next 2 years. With an experimental gene treatment. With recent cure of cells with HIV using crispr cas9. I believe a cured can achieve using a cocktail of drugs and gene therapy.  The process works by forcing the virus to awaken, while pumping antiviral to stop the spread of the virus. This would allow crispr cas9 to more easily to shred the herpe's DNA in the cell. This would also be combined with a TRIM5α Proteins to prevent the spread replication of the virus. Alot of this optimism comes from the gene therapy treatment that show results with current gene therapy treatments that appears to be successful. I am currently looking for people who live in Canada and are citizens or permanent resident. To join me in the process. If this is successful after a 12 month to 24 months treatment, a subject may be cured of virus permanently. This could also pave the way for future cure in other viral infection like herpes.

 

Requirements 

Living in Canada 

Covered by national healthcare plan.

Willing to be part of experimental treatment.

 

Any one who does not meet these requirements can comment but may not be able to assist with the process.

 

hmm i'm sorry i don't think it works like that.

correct me if i'm wrong but i believe the latent hsv virus is a dna stand that stays in your nerve cell and the active hsv virus are virions which is the dna in a capsid that can move out the cell and infect other cells.

so triggering the latent virus only allows it to produce more virions...

but i could be wrong so feel free to correct me.

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information seeker

Eventually, but it currently the process has begun

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information seeker

Well the main issue with herpes is the virus remain in he cell with a copy of own code. It is far more easy to snip at herpes when it is active than if it is dormant. Crispr can reduce the virus presences by %95 when active and eventually %100 percent.

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information seeker

I am currently working on a group to get a petition going

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Cas9

@information seekerWhat evidence do you have that you can awaken the virus?  If the virus is awoken, don't you think that the immune system will be engaged and cause inflammation or do you think the antiviral drugs will handle the infection and not cause inflammation?

Edited by Cas9

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Happybee

I have my passport and if you found a cure I would come canada Im working on my dual citizenship as we speak but I pray this is successful

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information seeker

I am actually seeking Canadian to admit in this task. If this process fail in Canada. I will attempt it again in Japan. Since Japan is less strict on gene editing

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information seeker

When our bodies are stressed, we release high levels of corticosteroids. Which can be used to awaken the virus. But first casp9 would be introduced into the body, and after corticosteroids would be used to activate dormant cell making it easier to snip the dna within the cell. The anti viral are there to help fight the virus that being realised from the nerons, but this process must be done multiple times to ensure you kill off all of the virus 

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Happybee

Please keep us updated and if you make it to usa then post plz

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MikeHerp

CRISPR / Cas9 has shown it cannot reach the latent HSV virus, only to stop replication after replicated virions are released.

Are you aware of that?  If so, what is your plan to get around that?

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Sls1983

This would be amazing if it would work gene editing is something I’ve took an interest in myself please keep us posted, thanks.

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information seeker

Well this won't be happening in Canada. I will try again in Japan. I will be seeing a specialist in STDs within 10 days.

Edited by information seeker

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LeftCoast

Would this research be conducted out of a lab or university? I am interested, but I would need more information. I would need to know who is conducting this research, research information/proposal and anything regarding patient safety. 

I live in Canada and meet this criteria. Please feel free to PM me. 

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information seeker

I tried to get a study approved, but failed. If you like you can talk to a doctor and see if you can get your petition through to health Canada

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