The paper can be summarised as follows.
The same sexual practices result in HSV-2 and HIV infection.
The proportion of people with HIV is proportional to the percentage of the population with HSV-2, not more, not less.
Good find. This is critical research as this is the first global estimate of HIV infections resulting from HSV-2.
Here is the original paper: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(19)30470-0/fulltext
I'd like to highlight some things. First, the Lancet is one of the most prestigious and authoritative medical journals in the world.
"The Lancet’s 2013 impact factor is 39.207, ranking the journal second in the general medicine category. It’s very difficult to be published in The Lancet."
Second, the results are pretty damning:
420,000 of the new HIV infections in 2016, were attributable to the persons having HSV-2. Risk of HIV for people with HSV-2, is "at least tripled".
An estimated 420 000 (95% uncertainty interval 317 000–546 000; PAF 29·6% [22·9–37·1]) of 1·4 million sexually acquired incident HIV infections in individuals aged 15–49 years in 2016 were attributable to HSV-2 infection. The contribution of HSV-2 to HIV was largest for the WHO African region (PAF 37·1% [28·7–46·3]), women (34·8% [23·5–45·0]), individuals aged 25–49 years (32·4% [25·4–40·2]), and established HSV-2 infection (26·8% [19·7–34·5]).
A large burden of HIV is likely to be attributable to HSV-2 infection, even if the effect of HSV-2 infection on HIV had been imperfectly measured in studies providing adjusted RR estimates, potentially because of residual confounding. The contribution is likely to be greatest in areas where HSV-2 is highly prevalent, particularly Africa. New preventive interventions against HSV-2 infection could not only improve the quality of life of millions of people by reducing the prevalence of herpetic genital ulcer disease, but could also have an additional, indirect effect on HIV transmission.
This is a good news / bad news story. It's bad news, because it means that many people who get HIV, get it because they had HSV2.
But the good news is that, as more studies are underlining how much HSV2 is as a driver of the HIV epidemic, more research will be focused towards HSV therapeutics and prevention.
I'm trying to find information about herpes on gums and it is harder to find than I thought. Is it possible to get cuts and sores on gums that are caused by HSV 1 or 2? And if so, would the sores actually be very painful, or just uncomfortable? Does anyone here get sores on gums where the skin gets swollen and warm, then the gum skin starts to peel away, leaving red open skin underneath? This is not related to poor dental hygiene, aggressive flossing or brushing, or a random cut or canker sore from eating something sharp or hard. Strictly on the gums. I would really appreciate any responses.