Positive News From Dr. Harvey M. Friedman of University of Pennsylvania

[hsv2fighter]

Dr. Harvey M. Friedman from University of Pennsylvania published their results, which is great news.

See the following link

Herpes Vaccine Experiment Prevented Genital Lesions in Animals

[Voyager2]

Thank God! We have TWO VERY PROMISING herpes prophylactic (protective) vaccines in commercial development: X-VAX is developing the Einstein vaccine and BioNTech is developing the Trivalent vaccine. One or both will make dating a LOT easier.    

[T9000]

10 hours ago, Voyager2 said:

Thank God! We have TWO VERY PROMISING herpes prophylactic (protective) vaccines in commercial development: X-VAX is developing the Einstein vaccine and BioNTech is developing the Trivalent vaccine. One or both will make dating a LOT easier.    

There's unfortunately still no indication that either of them are going to trial. It's taking an excruciatingly long time to get a major prophylactic vaccine trial up and running since the last one ended probably 15 years ago I think. It's a lot of wasted time.

[MikeHerp]

On 9/25/2019 at 2:13 AM, T9000 said:

There's unfortunately still no indication that either of them are going to trial. It's taking an excruciatingly long time to get a major prophylactic vaccine trial up and running since the last one ended probably 15 years ago I think. It's a lot of wasted time.

While you are technically correct, X-Vax did get $64 million recently to take their vaccine into human trials.  So I feel confident that one will proceed.  They've done extensive animal testing.  And $64 million should be enough for up to phase 2.

Regarding UPenn, the time line on that one keeps getting pushed back, but I feel confident that they are going into at least phase 1.  The last I heard was human trials beginning around the end of next year.

I really think both these vaccines will proceed to human trials.

You are correct that prophylactic trials can take longer.  But both Einstein and UPenn have already done extensive animal testing--they've been working on them for a number of years now.  

The GSK prophylactic vaccine trials took around 8 years--I think it ended in 2012, so not 15 years ago, and they weren't entirely finished when the trials were terminated because they found no effect.   So it can take a while, definitely.  I think it would be less than a decade, for sure.  The FDA seems to be inclined to streamline things and speed them up these days, so there's a little hope there.

Dr. Frieman said that the trials for his vaccine would take "at least 5 years".  That sounds a bit optimistic, but you never know.  

Anyway, I agree it's going to take some years.  But let's remain hopeful and support each other in the meantime.  

 

Edited September 29, 2019 by MikeHerp