U Penn Herpes Vaccine :

[RNY18]

https://www.acsh.org/news/2019/09/24/u-penns-herpes-vaccine-looks-great-animals-will-it-hold-humans-14303

"...There has never been a therapeutic vaccine against any infectious pathogen. Vaccines are prophylactic, not therapeutic. In 2017 Dr. Friedman told me "Right now, I don't believe that the vaccine would work well enough to be therapeutic. However, we are addressing this." (4)

Vaccine for herpes have been tried and failed (every time) for 100 years. We should all keep our fingers crossed for Dr. Friedman and his colleagues. An effective herpes vaccine would be a major milestone in the history of infectious disease research, especially since 11% of the world – more than 400 million people – are infected with HSV-2. ..."

[iFdUp]

You know, Dr. Freidman and Dr. Jerome share the same reserved enthusiasm and offer it to us with the same grace. Something about that manner of speaking makes me so much more hopeful. 

"Not all animal models of human disease are equal, ... Some animal models are terrible at predicting utility in humans ... other models are very good, especially those for infectious diseases." 

This is something that I was not aware of. 

"Twenty-eight days after 64 mice were vaccinated and then infected with HSV-2, 63 out of 64 of them had no detectable virus ... Of the 10 guinea pigs tested, eight showed no sign of virus after 28 days. The two that did have virus present had strains that could not infect other animals."  

So despite the number of Guinea Pigs showing symptoms after receiving the vaccine, the level of effectiveness was still enough to mutate the virus to the point it can no longer be spread. WOW!

Edit:

With the venerable Akiko Iwasaki independently working on a method to enable vaccines to become robustly therapeutic, I feel there is a chance the world might just be headed for a functional cure. With the success figures we have seen here and the very promising results from Dr. Iwasaki's research so far, this is looking like a great match. 

Edited September 26, 2019 by iFdUp
Additional thoughts

[hk81]

On 9/26/2019 at 2:11 PM, RNY18 said:

.There has never been a therapeutic vaccine against any infectious pathogen. Vaccines are prophylactic, not therapeutic. In 2017 Dr. Friedman told me "Right now, I don't believe that the vaccine would work well enough to be therapeutic. However, we are addressing this.

Isn't he forgetting the therapeutic vaccine against shingles? And is he making a statement against the research of dr.Iwasaki?

[Voyager2]

Sounds like it to me.