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Squarex Announces Positive Results from Completed Phase 2 Study of SQX770


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" ... it could be the first and only drug designed to prevent herpes labialis outbreaks to receive approval from the U.S. FDA."

So this is being recognized as something to PREVENT an outbreak. Do we have a potential functional cure?

It feels like we are approaching the point of a drug cocktail being able to completely suppress herpes virus. 

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I have researched SADBE extensively. Essentially, it causes one's immune system to act more inline with that of immune systems which show no symptoms of HSV infections. In other words, most people hove mild-to-no symptoms, while others have outbreaks. SADBE modulates the immune system such that it behaves a lot more like the immune system of someone who has little-to-no symptoms.

Unfortunately, I couldn't find a doctor around me who would prescribe it. They said the treatment is worse than the cure... When I know I only need a small amount applied to my arm. It will burn and itch, but I am willing to accept that. Still, no luck...

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43 minutes ago, ManagingIllness said:

I have researched SADBE extensively. Essentially, it causes one's immune system to act more inline with that of immune systems which show no symptoms of HSV infections. In other words, most people hove mild-to-no symptoms, while others have outbreaks. SADBE modulates the immune system such that it behaves a lot more like the immune system of someone who has little-to-no symptoms.

Unfortunately, I couldn't find a doctor around me who would prescribe it. They said the treatment is worse than the cure... When I know I only need a small amount applied to my arm. It will burn and itch, but I am willing to accept that. Still, no luck...

Don't you have to have a positive test to be prescribed this?

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On 10/7/2019 at 11:12 PM, iFdUp said:

" ... it could be the first and only drug designed to prevent herpes labialis outbreaks to receive approval from the U.S. FDA."

So this is being recognized as something to PREVENT an outbreak. Do we have a potential functional cure?

It feels like we are approaching the point of a drug cocktail being able to completely suppress herpes virus. 

Between this, UB-621, and Pritelivir, all of which are showing promise as suppressive options, any form of combination therapy could atleast disarm the virus temporarily. True story, The doctor who discovered the SADBE compound as a treatment actually has H himself... Its no wonder he has so much faith in it, hes used it to change his own life.

An effective drug alternative is a closer reality than crispr or a vaccine at this point. Something is 100% better than nothing. Interesting times ahead indeed.

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On 10/7/2019 at 11:46 PM, ManagingIllness said:

I have researched SADBE extensively. Essentially, it causes one's immune system to act more inline with that of immune systems which show no symptoms of HSV infections. In other words, most people hove mild-to-no symptoms, while others have outbreaks. SADBE modulates the immune system such that it behaves a lot more like the immune system of someone who has little-to-no symptoms.

Unfortunately, I couldn't find a doctor around me who would prescribe it. They said the treatment is worse than the cure... When I know I only need a small amount applied to my arm. It will burn and itch, but I am willing to accept that. Still, no luck...

what do u mean ur arm where do u have it

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20 minutes ago, Chicagonow said:

what do u mean ur arm where do u have it

This is designed to be put on your arm and affect your systemic immune system.  It does not get put on the location of the sores.  

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3 hours ago, The said:

Between this, UB-621, and Pritelivir, all of which are showing promise as suppressive options, any form of combination therapy could atleast disarm the virus temporarily. True story, The doctor who discovered the SADBE compound as a treatment actually has H himself... Its no wonder he has so much faith in it, hes used it to change his own life.

An effective drug alternative is a closer reality than crispr or a vaccine at this point. Something is 100% better than nothing. Interesting times ahead indeed.

This is what I am feeling as well.

I feel the path forward that is most likely to come 'soon' is the one that has been tried. 

Drug cocktail is potential for a functional cure right now. The only issue is cost-effectiveness.

I'm not sure how you could combine SADBE with the currently non-existent Pritelivir/Acyclovir combo pill and keep things affordable.  

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  • 2 weeks later...

You can always order that 1% vial from Turkey or wherever...I did...can't see I noticed anything...who knows, after reading I did get it out and smear it all over my arm...i'll let you know if I stop tingling or anything.

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I got my hands on some 98% purity SADBE. Yet to test it out as it obviously needs to be diluted down first. Does anyone know how to make a DIY topical solution, i.e. what to use for a filler? I'd try first with a 2% solution as on the studies, or maybe 5% to play it safe.

I saw no difference using the Turkish 1% SADBE that has chilli as an igredient.. but I couldn't apply it topically to the outbreak. I don't know what usually goes into topical solutions as fillers. But had a look at e.g. Rogaine Minoxidil solution for hairloss and it has: Inactive Ingredients: alcohol, propylene glycol, purified water. Well, those are all something I can get my hands on, but percentages of each would be good to know. 

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  • 2 weeks later...
On 10/22/2019 at 4:44 PM, Kurdt01 said:

You can always order that 1% vial from Turkey or wherever...I did...can't see I noticed anything...who knows, after reading I did get it out and smear it all over my arm...i'll let you know if I stop tingling or anything.

Hahaha....I ordered from Turkey as well.  I was like what the heck, why not since it's only 1%.  I was more afraid of burning from the capsaicin  in it...LOL   I didn't see any changes either. 

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I believe the solutions used in the clinical trials are 5%. (Do check though.) This is just to say that 1% solution might not be effective. @viralfrog you're right, some drugs use compounds to assist in the uptake of the drug. Minoxidil solutions use alcohol to enable to drug to have a greater uptake on the skin

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